Illegal: So kaufen sich Reiche den perfekten Körper

There is a drug currently being developed that is also intended to enable muscle building without moving. And Eli Lilly is a very large pharmaceutical company, has already invested around 50 to 100 million in it so far. Eli Lilly is discontinuing the research. Nobody knows why. For example, another molecule is Cardio from the pill. Mice had 70% more performance, 25% more fat burning, and lost weight. Just by taking it. I use it every time I feel like I'm getting sick and then it doesn't happen. I use 25 mg for sleep. My sleep values have improved extremely since then. This podcast really shocked me. It opened a door to a world I didn't know existed. And I am sure that most of you also do not know that this world exists. That almost all doctors do not know that this world exists. At its core, it's about using the latest scientific findings to make yourself healthier, fitter, stronger, and more beautiful. And people are already doing that, people with money and influence are doing that. And it's long [music] not just Osemp. My dears, I wish you good insights with one of, or perhaps even the leading biohacker in Germany. And if you want to support me and if you want to support me in building the Switzerland of podcasts here, where all opinions, but also the latest scientific findings are heard, without us having ideological reservations, then gladly subscribe to unscripted on YouTube, Spotify, or wherever podcasts are available. So my goal today is to understand with you how this whole biohacking thing works. And biohacking is a very, very strange word. Yes. for actually being healthy or rather real doping, and I still don't know how it works or how it works for me, and I actually ask a lot for myself because it interests me, as you know. Mhm. First of all, there are medications, one group of substances are medications, then there's a group of substances that are food, correct. And then there's a group of substances that are basically in food. These are then macronutrients like proteins, fats, carbohydrates, or micronutrients like [sighs] magnesium, trace elements, vitamins. So. And then there's something that's kind of like something in between. Um, you're talking about peptides. So. And then I looked at what peptides are and it was somehow complicated, but I tried to understand it simply for myself. So, there are substances that you take and then your body works better. But they are not medications and sometimes not food either. Mhm. Good. Yes. So. Um, and the concern or I'll do it differently. I'll do it differently. I think we've gotten very, very complicated in my head. So. If I go to the gym again and see people over 60, they are mostly on the stepper, maybe on the treadmill, walking around at a pulse of 90 for 12 minutes, but nobody is lifting heavy weights. So, that's one thing. At first glance, you're missing heavy weight training, and you're missing protein, macronutrients. So, and presumably you're missing testo, and testo is probably the biggest thing that people are missing, or rather, they would function better if they had more testo. So, is that true or is that nonsense? Age-related, certainly. Mhm. But even age-related, it's a law. Definitely. So, the decline of testosterone with age, so from the age of 30 upwards, leads first to sarcopenia, i.e., age-related muscle loss, secondly, of course, to bone loss, bone substance, which in turn leads to ailments and which is actually one of the main causes of death for most people, apart from cancer in old age, which is also relatively common. Um, so it's also interesting to look at where that comes from and whether one can intervene early. Um, so yes, definitely. The rest is of course libido, sex drive, and things like that. Um, insulin sensitivity decreases, because, for example, in favor of disappearing muscle, more body fat also accumulates. This means that here too, more estrogen potential over time, more risk of metabolic syndrome. At the same time, movement also decreases. One can exaggerate and say that this is a cascade effect, which is certainly due to testosterone deficiency on the one hand, and on the other hand, of course, also to our society, because it is socially accepted that if you work more, you do less for yourself. That is the norm, you justify it with that. One could compensate for quite a lot of it by simply being more active, but over time you are fighting against windmills or the hormone that needs the signals for it or gives the signals, so that the effects that you have to have or should have then occur. So, you can say that. My dears, without wanting to spoil it for you, but this podcast with Iron Mike really shocked and fascinated me at the same time. It's a lot about testo and all the positive things it does for men. And now there are various little aids and helpers. We'll talk about them in a moment, but there are also simple things that can help you optimize your testo balance. There's a lot of fake stuff on the market, but there's a new product from ESN, ESN Testo Support. It contains, for example, Ashwagandha, it contains Boron, but also Fenugreek extract and other things that are scientifically proven to help optimize your testosterone. If you want to optimize your testo, in my opinion, one component is still missing, and that is Omega-3. But you should be taking that anyway. That means I take ESN Essentials, which contains Omega-3, Vitamin D, and Magnesium, and also the new Testo Booster. It's brand new on the market, I'm trying it out, but it's scientifically confirmed that it actually works for optimization. If you're up for it, then feel free to use my code unscripted. It gives you at least always 10%, but always guarantees the best price. ESN code unscripted. You'll find the link in the video description or in the link [music] tree. Simply put, one could say, the more testo, the better. [laughter] Yes, that's actually not true. Why isn't that true? Well, it's true as long as, it seems to me, you don't cross certain boundaries. That's true. Then we're back on track. Then we're back on track. Yes. Yes, but the more would also mean, like, unlimited, right? That you have a very, very quickly occurring point of diminishing return, which simply means that from a certain point on, you no longer have positive effects, but predominantly negative effects, and I find it a bit funny. I notice it on LinkedIn too, I'm new to LinkedIn and it's like Facebook, there are a lot of new entrepreneurs who are quite open-minded. Um, that's always very cool, but there are also people, you know, sometimes even doctors, who say things and um, and represent stereotypes that make you cringe when you think they're treating you. Um, and there I notice, for example, that testosterone or many other things are mainly associated with some kind of stereotypes and the situation isn't really clear: what is actually the effect, what are the signaling pathways in the body, and what is actually a long-term effect? Many talk about long-term effects. They know neither the definition nor the effects themselves. Then many people say there's no data in humans about it, they just don't know the data. I know it, and there is data in humans for many things, and for some, not. But what if there's no data in humans? Then you just have to know the signaling pathways in the body and compare whether they are the same in humans to at least be able to give an assessment. And that means it's not always this black or white, that's something that always annoys me. And I stumbled into this topic of biohacking out of my own motivation because after, I don't know how long it was, years of trying competitive bodybuilding, and then also for financial reasons, I had a bit of a harder time earlier. I was broke with everything and fled to Berlin and tried my luck there and realized I couldn't do bodybuilding anymore, well, for financial reasons, even though I really enjoyed it. I started coaching because I was already producing a lot of knowledge content, always reading a lot and being very interested. I was also lucky enough to have early access to very good sources through my coaching and then earned money and experimented on myself. So I started with myself. I first went through the whole steroid topic, let's say, by investigating it first, then testing it on myself, seeing how it affected me, checking blood values, even going very high, trying many things, building a lot of muscle, and then realizing I was doing well, it was getting better and better, but I didn't want to be a bodybuilder on stage anymore, I wanted to coach people, which I've been doing very successfully all along. Why am I doping myself? So, what is my goal? I was 113 kg dry, I had proven that to myself, and I don't want to be a bodybuilder. And then I thought, I'll go to a cardiologist now, because I've been doing blood tests with everything all along, but I need to know how my heart is doing, right? Because I had read quite a lot about it in studies and I was clear, I had actually expected to have some form of left ventricular hypertrophy, i.e., an enlargement of the left heart, the left ventricle, however you want to call it, which already indicates an unfavorable direction towards heart attack risk and various other things. Stop, stop, we've gone very, very far. Let's go back to doping. So, you're sitting in the gym, lifting heavy weights, saying, I want to get bigger, bigger, bigger. Then some dude comes up to you and says, "Listen, do you want to buy something?" Um, when you talk about doping, or people talk about doping, what does that mean specifically? It's very broad. Um, I would say doping is when you go beyond a physiological dose, no, I would say that's even a bit of biohacking, we can talk about that later. That's even over-optimization. That's achievable in a healthy range, and I know many disagree, but I see it in blood work. If you go beyond this range, where you still have a health benefit. Sorry to interrupt. You're so deep in the scene that for you the question is, where is the borderline to doping? If a normal person goes to the gym for the first time in their life, they learn bench press. If it goes well, they learn bench press and don't just do leg curls. So. Then someone says, you should drink a protein shake. And then they go to the doctor and say, look, I'm going to drink protein shakes now. And then the doctor says, if it goes really badly, you have to be careful about your kidneys, because too much protein is really dangerous. So. And that's basically stage zero, so you realize, okay, I need to consume protein, and then you say about one to 2 grams of protein per kilogram of body weight, if you weigh 100 kg, 100 to 200 grams of protein per day. So, roughly, right? [sniff] You quickly realize that the ham sausage on your sandwich, which you eat in the morning and evening, is not enough, and a protein shake with about 20 grams of protein is also not enough. So, then you play through it a bit. Okay, how can I integrate protein into every meal? How can I get high-quality protein? What, no, how do they have as little fat as possible? How can I, I don't know, make them cold? Meal prep. So, that's basically the game you go through when you go to the gym and develop it as a hobby, and then you realize, okay, nutrition, that's the big thing, man, eventually you realize nutrition is ultra important and heavy weights are ultra important, and then you have, that's the gym one-on-one, two essentials for sure, and then we get into this doping area, so to speak. Then you say, I'm drinking two protein shakes a day, I'm tracking my calories, I'm doing meal prep, I'm doing a two-day split, I know roughly what I'm doing. So, and that's still the normal guy, so to speak, a gym dude. And then the line comes, for me, when someone comes with illegal substances, so and that would be for me, then the door to doping opens, because I have something, we'll do this, I used to be in a gym where in the training sessions, he had a roller shutter, which was always adjusted so that you couldn't see in. So, that was the moment when they weren't talking about protein anymore. So, it seemed to me from the outside, as I sat there, but where it was about the hot, about the hot stuff. So, if someone is sitting behind that door now, and they've trained well, they have good nutrition, and now it's about doping. Yes, I heard there's more. What is doping then? Mhm. Then I would actually say, so, what I started to explain, I would try to package it a bit differently. Um, doping is from the moment when you really say, you go significantly beyond your production. That means, if you just start taking testosterone, and you have an X-fold of what you would naturally have, and actually, a single dose of testosterone would be enough, because with testosterone, I would clearly distinguish, do we have TRT, do we have a bit of doping, or do we have doping? Doping is the typical thing that almost everyone does, right? This typical 250 mg a week, that's where doping starts. There are people who say that's TRT, it's not. You are at an X-fold of your actual physiological range, and even if the data shows that you can still have relatively few side effects in the long term if you do everything right, we are already in the direction where we can definitely say you have more risk for the heart and so on in the long term, right? So, that's doping. Doping, I would say, is always the door that then, so you don't just stick with testosterone. Very few people do that. That's why doping is always also it goes in so many different directions. I've met very few people who stick with testosterone, at least those who go to 250 mg, where they say, I want to dope. Then immediately comes, how is it going? What else can I take? What can be done for this? What can be done for that? And I would define doping as really when you solely focus on muscle building and try to push everything else into the background a bit. You try to optimize a bit, right? What breaks, I try to fix quickly, but the overarching goal is muscle, and then you are a doper. Everything else would be biohacking, for example, if you say, I'm trying to push it up so high that everything else remains healthy, and then I'd rather go through many other signaling pathways that I can all upregulate at the same time. By the way, I do that for doping. I still advise bodybuilders, not as much as before, but for doping, I've also developed a kind of anabolic matrix, where it's like many different signaling pathways that all produce anabolism are ramped up and produce similar effects to someone who is doping, but not as dangerously, because if you don't push every pathway up, but all a bit lower, which have the same effect or through different pathways, you have less risk if you understand what they do to each other, right? That means, um, doping is fundamentally unhealthy. So, you can, if you're lucky, get away with it. Especially if you do it short-term and only testosterone. Many get away with it quite well, but doping is always a certain trade-off for health. Clearly. Okay, so that means, um, for you, from the moment I possibly get a testo injection, it's not doping yet, but we're entering an area you call biohacking. But, I would say a critic would say, okay, you can eat well, you can also have your protein shake, that's all okay, then you can take a few supplements, a little vitamin D, Omega-3, a little magnesium, so you have better muscle recovery. But the moment we start taking hormones, people would say, okay, that's a doper. So. And in essence, that's the guy who wants to get as big as possible. Either he's a pro bodybuilder or I don't know, he's in a motorcycle club and look, I need mass. So, how can I get as much mass as possible in the shortest time, and then some shady dude comes along and says, look, I've brought you some syringes, inject them, and you'll get super big in a year and look like not a lanky person. So, and then he injects it, and it works, muscle growth increases, and you say, yes, there are risks, like the heart muscle also grows, and then there are many, not many, but quite a few bodybuilders who just drop dead because their heart is broken. So. That means there's this basic principle of doping, that if someone wants to be big with, let's call it medically hormonal help, then it's possible. Then you go full throttle, look, maximum, and just try not to fall over. Yes, that's doping. So, and then you say, yes, wait a minute, one could now also take less of the substances that the doper takes, or possibly different ones, then you would have the positive effects like muscle gain, but the negative effects like falling over, being dead, possibly not. And that's basically the area when you talk about biohacking, it's everything, let's say, beyond nutrition, maybe also a bit of nutrition, but everything that is in addition to nutrition, but before doping and before therapy. Is that correct? I would try to categorize it again. Basically, close. Nutrition, training, supplements are an incredibly large part of biohacking. I would even go so far as to say that if they are not optimized, the rest is almost useless. So, you're fighting against windmills. You can compensate with a lot of money. We've tried that here and there. Difficult in the long run. Therefore, I would say, first, that's the first part. German biohacking, as I jokingly call it, is nothing more than that. So, in Germany, there are really people who say, I'm a biohacker, I'll coach you or something, and then they give you magnesium for sleep, and that's biohacking. Well, I would say, I take a bit of that, but I go beyond that. I do what is understood as biohacking in the international context, where the boundaries simply disappear, you have no, you just look, regardless of where something comes from or where it is listed, you objectively assess what it does and what the benefit-to-risk ratio is, and does it do anything for me? And if it's good, it's done, if it's bad, it's not done, right? But only the objective data matters, not any country that says this is allowed or not allowed, or any people who say this is allowed or not allowed. And therapies are part of it. So, I've been doing a project for years with three private doctors from Germany. We do TRTs, i.e., according to American standards. And actually, the doctors contacted me when I was complaining a bit about German TRTs in public, and then they said, we would like to offer our help, because we see it like you, right? Let's work together. And it works wonderfully. And that's also biohacking, because in the end, it's an optimization. Of course, they have a deficiency and they need it somewhere, but I would definitely include such a therapy in that. Therefore, I would say, everything that concerns optimization is biohacking, and strength training is definitely part of that. Those are the basics, you have to master them. Your sleep is also part of it. How is your sleep hygiene? And if all that is right and in place, then we look at what else we can get out of it. And that's not much, but it makes a significant difference to what others are doing, a very, very big one, because the little bit you have more gives you significant advantages in every respect. And that's what I focus on, because I find it extremely fascinating, right? That sounds to me a bit like if there were no toothpaste, but only dentists who say, look, the tooth is broken, we'll pull it out, then you won't have any pain, then I don't know, the other tooth won't be affected, and then someone comes and says, look, if we put this cream on our teeth every day and brush away the dirt with a toothbrush, then you don't need to go to the dentist at all, because then the tooth will remain white, it will be beautiful, it will be healthy. And then the dentist says, but but you can just leave it like that. I'll pull it out if that's the problem. And accordingly, toothpaste would actually be a form of biohacking if it weren't already so established in every supermarket. Yes, yes. That sounds pretty good actually. Or sunscreen, for example, is [clears throat] also an active ingredient. You know sunscreen works. It's not magic. We apply it, like an anti-wrinkle cream, where nobody really knows if it does anything, if it does nothing. If you put on sunscreen, you don't get sunburned, if you don't, the skin burns. It's relative. Then some pseudo-health advocates would probably disagree with you, but I see it exactly the same way as you. Yes, funny anecdote. Um, a friend of mine once said, you know, you can live on solar energy, and that's the big thing, and when I say I need to change my metabolism, he lay in the sun in South Africa for 8 hours. Yes, he was still hungry, but he was bright red like a crab. So, reality intervened very, very strongly. He said, look, the theory is good, it didn't quite work in practice, and he ate normally again afterwards. Especially since one must consider that skin cancer often manifests decades later, and at that moment, the foundation might have already been laid, right? You really have to be careful with something like that. Yes, okay. But there are, so to speak, there are means that we use that have become part of daily routines like toothpaste, which could be called biohacking if it weren't already so established. So, and you are looking for the next toothpaste, so to speak, the things that optimize without them being broken. Nice. Yes. Alright. So, then you said you started with TRT and you ranted about German TRT. What is TRT and why did you rant? That was still during the coaching time I did for bodybuilding. During that time, I educated myself quite a lot about hormone optimization, because I was always like, I noticed that many coaches, when I asked them about things that interested me, couldn't explain to me why it was like that. They could only tell me, that's how it is. That bothered me. So, I started searching. Fortunately, at that time, I had access to people who gave me access to doctor portals like Ambus and Co., where you can read things directly. Then pharmacists I worked with, for example, gave me some information about medication lists and things like that. Then I looked for studies, and then it went on like that. [cough] Then I finally understood [clears throat] how hormones work in the body and based on that, I started working and also creating content. The content was well received, and then the first ones came and said, I'm on testosterone replacement therapy, TRT, and my doctor does XY with me. For example, he said, my doctor gives me 125 mg of testosterone enanthate every 14 days, for example, which in effect often leads to side effects, especially in the beginning. We can perhaps go into that in more detail later. First, status quo. Can you adjust me correctly if I come to you? Or he said, I'm getting the typical German TRT, that annoyed me the most, a long-acting testosterone, the so-called Nebido. There are studies in which residual testosterone levels were detected after 3 months. Residual level, residual metabolites, not even values anymore. And then they said, that gives us a reason to inject someone only every three months. Now you can imagine that if you need a value like this and only get your injection again when it's down here, that you might not feel quite so good. But that doesn't matter in that sense, and many such people have reported, saying I feel incredibly bad. The peak of the whole thing was a transgender person who came to my coaching. I didn't understand at first, he really looked like a man, like a young man. And then it was confessed to me, I was my wife, I said, okay, cool, so what do we do? I have a problem with my testosterone, because my doctor does Nebido every three months, and after about 6 weeks, my voice gets higher. and I get mood swings, and I notice I'm slowly becoming a woman again, at least in part, and that's mentally exhausting me. I adjusted him, and it never happened again. In the end, after all these stories, I got angry because I thought, because I tried to contact some doctors, the treating ones, they didn't want to talk to me. Logically, I understand that to some extent. But at some point, I asked myself, because it's so simple, you can sometimes just look at what they do in the USA, why, how are the studies, and the studies are all there. Why, why don't they do that? Then I looked at the guidelines for hypogonadism in Germany and said, hypogonadism is testosterone deficiency, exactly the umbrella term, and I even saw that the guidelines are not necessarily binding. That means you can decide for yourself to a certain extent, and I came to the conclusion that it must be largely ignorance or ignorance. And then I made a video called German TRTs are shit. And that got quite a few clicks. And then a few days later, I received an email in my coaching applications, because he probably didn't know how to contact me. And there the first doctor had contacted me, saying, "Hi Mike, I'm a doctor, I saw your video, I would like to offer my help." And then I met him, and a year later, we actually started the project, our own. Now there are three private doctors from all over Germany. I don't want any more. So, we also get applications for it, but I trust these three, I work with them very gladly, and we have issued hundreds of prescriptions in the meantime, and people are doing great. Why can't the so-called normal doctors do that? I think we have many, many different stories here. So, first of all, it's a bit about the medication regulations that exist. You have to work through medications according to a certain list, which is mostly cost-oriented for insurance. That means the first problem is insurance doctors. are, so they can't help it, but they are ultimately bound by certain guidelines because the whole thing is financially prescribed and they can't act differently because there's a budget. I honestly don't know the relation or order of this list for insurance doctors. But I do know that the first thing they always prescribe, if anything, is gel. But we'll get to that later. It starts further back. Our guidelines for hypogonadism are relatively conservative compared to, for example, those in the USA. That means it's very difficult to have a deficiency in Germany at all. This is due to the values and also to the reference values of the blood count. They were taken from much older people at some point, and especially the average. And then we have, what does the average consist of? You need an average of values, an average of blood counts. Who gets their testosterone tested? Mostly people with a deficiency. So, you don't have a healthy reference. This is put into better perspective in other countries than in ours. Here, the value is set so low that I tell you, if you really fall below the reference here, then you have a huge problem. But you already have it much earlier. And accordingly, that's where it starts. They are naturally trained accordingly. If they don't educate themselves further, they believe they are doing the right thing. So, perhaps they are not really to blame. Then it continues with what I am allowed to use and what not. What do I want to use? And mostly it's testosterone gel, which is not optimal for most people. And then the will is missing, and probably also the time, to educate oneself in this regard, because one thinks it's a niche topic. We have a stigmatization in Germany, that testosterone is dangerous and so on. That means one doesn't want to tackle this topic too much here. One doesn't want to do it, and I think that's where it hangs somewhere. Those are, I think, most of the things we have, and therefore [sighs] there is a not insignificant part of German society, i.e., men, who do not feel well looked after there. And we are noticing this more and more since we've been doing this. Yes, you say they don't feel well looked after, but as your previous stories showed, they are not well looked after because if I so

I need a massive testosterone level, and it simply drops over time, and I feel bad after 6 weeks. Uh, that's not, yes, that's subjective feeling, but if the answer is, hey, you just have to administer it more often so that the level is more constant, that seems very, very, not like a personal feeling, but factually correct. Um, at least for me as a layman, but what do I know. Okay. That means, in this testosterone world, uh, it's like, if I were to compare it to a car, as long as my car still drives 120, everyone says it's great, and if it's a Lambo with 600 horsepower, they say 120 is irrelevant. It's great, you can drive on the highway with it, you can drive in the city, it starts, it drives, it brakes. So, and we would never allow that with a car, that you can drive a Lambo at 120, but something would be done about it. But we Germans, especially when it comes to our health, don't do that, if I understand correctly, most people don't do that. And the system is designed in such a way that it's basically based on this 120, if you manage that, then everything is fine. Parentheses, yes, a Smart car now drives 140 or 150, so you're really the slowest. So what do you do when you realize, so what does normal therapy do as a doctor or as a patient, you go to the doctor. Listen, I think I have a testosterone deficiency. So, then the doctor takes the blood test and says, "Yes, okay, no, you don't." And in essence, you say, "Yes, if you had that, you'd be dead." So, actually, no one should be diagnosed with a testosterone deficiency by a doctor because the reference ranges are so small. But it still exists, so that's the German TRT, as you mean. So TRT for people who are really almost dysfunctional. So, and at the beginning, we had more this, the more testosterone, the better. So I heard that with testosterone, there was a study where they took people and said, look, you train, you don't get testosterone, you're not allowed to train, you only get testosterone, and the others do both, and the people who only received testosterone had more muscle gain than the people who trained and didn't receive testosterone. Correct. Correct. But that, I can address that right away if you want to finish, or I, no, go ahead. Okay. Um, I know the study. It's correct in absolute numbers. The problem was the measurement of the so-called lean body mass, meaning fat-free mass. That sounds logical to all of us at first. Fat-free mass must be muscles. That's not true, of course. Fat-free mass is everything except fat. Accordingly, we have to understand that the intake of testosterone interacts with a certain system, called the renin-angiotensin-aldosterone system. This regulates, among other things, sodium, water balance, blood pressure, and so on, various things. And through this interaction, we store water due to sodium retention, sodium reabsorption, as we call it. So, we store water from the moment of testosterone intake, especially in the beginning, we store intra- and extracellular water. That means we store water in the muscles, if you will, because muscles are formed, but also outside the muscle. And that's an incredible weight change that we have. If you also don't move due to no training, we might assume they moved a bit more before, at least a bit, then you naturally gain weight. This weight, in the end, if it's lean body mass, is not muscle, at least not only. And these are the big, as they are called, confounding factors, right? So that kind of blurs the picture a bit. That's how it gets confused. Accordingly, this study is known, and it's also true that testosterone in itself simply builds muscle. That's its job. The androgen receptor, the stimulation, and so on, it does that. The numbers, they are outrageous, it makes no sense. Um, accordingly, it's also a relatively well-known study in science, which you take with a smile and say, "Yes, it's nice, but not entirely true, right? But fundamentally, yes, I just have to put it in perspective, it wasn't that much muscle." Okay. So, that means testosterone is a hormone produced by the body, and then we said earlier, the more testosterone, the better in certain areas. So, if you just give the average man, if you say tomorrow, look, tomorrow you have 30% more testosterone, you had natural testosterone until now, and tomorrow you have 30% more, then most people should feel much, much, much better in terms of having more muscle or building muscle faster, feeling better, having more energy, sleeping better. Those are the effects of testosterone. So, + 20, 30, 40% is great for everyone at first. Correct, or am I missing something? Yes, it depends on the individual effects of the medication, because every medication has, no, no, I don't mean medication, but if we generally just, I don't know, we would tomorrow, I don't know, a special radiation from aliens that says, do you want 30% more testosterone, and we say, we have to think about it, let's say there are no side effects, then yes, then more testosterone is better, it's unconditional. And if someone were to walk through the door who was a biochemist, they wouldn't say, "Yes, hold on, Mike, you forgot that." Mhm. So, more testosterone is better in this + 20, 30% range, generally good, I agree. Okay. Um, from where, if we are now negotiating with the aliens, how much percent for the general population, without knowing the patient, would you say, hey, dear aliens, + 70 is too much. At + 70, we have to look individually, how much, if you walk through the streets and look at people, how much testosterone do they lack for an optimal life? The problem is that we have a very big obesity problem in our country, and more testosterone is good. Only, the more overweight someone is, or the more body fat someone has, the more active a certain enzyme is, which is found in body fat, if you will. This enzyme converts testosterone into estrogen. The enzyme is called aromatase. That's why in these therapies, we are actually, we're back to biohacking, if someone is overweight, due to the testosterone, because testosterone is lacking, we try to get them off the excess weight as quickly as possible. For example, through GLP1, we can also talk about that later. So, through Ozempic and Co. There are now much better things. Um, not yet approved, but there we are again with biohacking, and that means it's extremely individual. I would say, most people are probably well-advised with 10 to 20%. Almost no one will have any problems, because everyone is a bit below anyway. Most people would just optimize themselves. However, it is true that one thing is a homeostasis value and optimization, the other thing is feeling better. So, being a bit in the upper reference range, you still feel that, you feel a difference, you're already heading towards supraphysiological, and there it can happen, the more body fat someone has, for example, the more estrogen it will probably turn into, and from that, further side effects can arise, and the more body fat someone has, the more the weight gain will probably be due to water in comparison. That, in turn, burdens the heart, for example, right, blood pressure, and so on. So, 10 to 20 is probably safe for everyone. I would say, then there's the general population that is reasonably healthy and in shape. They could benefit from significantly more. How much approximately? Oh, that's almost speculative. 30% maybe? 30? Yes. Uh, if we talk about the reference ranges, someone who has little potential for side effects could probably be in the very upper reference range and function relatively well. Although exceptions prove the rule here too. We also have people with little body fat who still aromatize a lot, meaning they produce a lot of estrogen, right? Um, but there are few of them, right? We just have to say that, there aren't that many of them. And that's why, although I like testosterone very much, I am cautious, because in the entire therapy over the years, we have seen with so many people that it has different effects. But roughly speaking, you can say that in TRT, in simple substitution, you have almost no negative effects. That's what we see. Um, everything beyond that, that's where it slowly starts. So, the higher the testosterone curve goes, the more you have to look a bit to the left and right, because with some people, it starts. But the better the surrounding factors are, the less. So, here too, it's worth taking biohacking in its basic form seriously, by saying, training, nutrition, sleep, stress management, whatever, right? So, all of that is relatively important, although testosterone does make you a bit more stress-resilient. That's also a welcome effect. If we are now negotiating with the aliens again and they say, "Okay, we'll set our emitter to + 20%, with that we can irradiate everyone," and then you say, "Okay, anything over 20%, we'd have to look, some would benefit from 30, 40, 50, 60, maybe even 100%." Somewhere, however, not 1000%. M%. We really have to say, okay, there are positive effects and there are negative effects, like, you get broad, you become an animal, but your heart also becomes an animal's heart, and it can stop beating. So, and you have to balance that, but slight optimization is fundamentally good at first. Is there another substance, hormone, or similar that the aliens could send instead of testosterone that would be better to achieve something? [laughter] For people, if we say, I want a better life, how can I achieve that? So, then I have no idea, I've read a bit about testosterone, and testosterone apparently has, the more testosterone, the better, an unspeakable number of advantages without disadvantages within certain limits. So, if I think about it now, I, as a layman, can't think of a second substance or hormone where I think, okay, if I want to improve my life, and I could choose something, what could I wish for, besides testosterone, would probably have the biggest impact on well-being, health, and everything, or? Yes, we have to say again, because I think otherwise there will be many misunderstandings. The increases we just mentioned, they only go by the numbers if we assume an optimal value, right? So, from a deficiency, you can of course increase by 400-500%, clearly, right? But I would agree, maybe even a bit higher, if I think about it. So, yes, I would say. Testosterone has very, very many of these effects, and it probably takes care of a lot of what we consider positive all at once, because bones get stronger, muscle mass is maintained, blood sugar metabolism improves, libido generally improves significantly. Actually, you're doing well with quite a lot of things. The neuroprotective effects of testosterone are in, so positive effects on the brain, health, and so on, I would say, you have in the low range. Steroids with long-term use and overuse can have the opposite effect. You have to say that too, of course, that's very important. But generally, you're fitter with everything at first. It's not for nothing that people with a deficiency also have so-called brain fog, right? You know that, they can't sleep, can't concentrate, can't get out of bed. So, you're really missing the drive hormone, and if we define drive now, then I would say, yes, testosterone would probably, if you're looking for an all-rounder, take care of most things. The rest would have to be stacked elsewhere. But to replace testosterone alone and take it away will be difficult because it takes on too many good tasks. Okay, you, if you didn't have to take it away, but if you had to name a second substance instead, or I don't know, a blood value, what would be the second substance or blood value that is the lever for optimizing the masses and longevity and well-being of the masses? For most people, it would be something related to blood sugar, I think, because most people have relatively high long-term blood sugar values or are already tending towards metabolic syndrome. But various blood values are connected to that. So, it's not just one. So, that would be quite important. If we move away from blood values now and just ask, what ability or what else could be done? I would actually say, testosterone doesn't do that directly, but only indirectly. I would probably, to make people even healthier, do something for fat burning at the same time. Simply to prevent people from building up too much fat in the long term and also to help them lose more fat. Maybe even a bit of appetite control, something in that direction. And if you were to put someone on testosterone and supply them with this other medication or experimental medication, you could actually say that the person builds more muscle, loses less muscle, has less hunger, but also burns more, even at rest, and can still get the pharmacological effects or pharmacologically generated effects of endurance training on heart health and so on, even if they hardly move. And best of all, liver fat would even be burned, and they would become metabolically healthier. That would be feasible. At least it looks that way so far. Okay, we're already very deep into it. We've just talked about testosterone. That applies to men, it doesn't apply to women. So, if we talk about female testosterone levels, that probably wouldn't be the longevity or life satisfaction factor for women. If you just give them 20% more testosterone with the aliens' emitter, will they feel better? Women also have more testosterone than estrogen, just like men, right? So, the thing is, around menopause, we have quite a few women who we can now successfully supply with a testosterone gel in that case. A gel is useful here because it can be dosed very low, right? So, women also need testosterone. An androgen deficiency in women leads to exactly the same things. So, they feel incredibly bad. It's just that typically, women, especially at a younger age, don't have such a severe deficiency. That means, with women, you actually have to look very closely at the blood work, what's going on? What's missing? Is anything missing at all? And then, before intervening so drastically, I would actually look at the energy balance for women, um, at metabolic health, perhaps also look at the precursor hormones before the sex hormones, like DHEA and Co, to see if something can be optimized there, but yes, fundamentally, a woman, at the latest when she has a deficiency, would have the same or very similar symptoms and would benefit just as much if it were increased. And I would, if we stick to percentages, I would almost say similarly. Because it's still relative to their baseline, right? That means you can't assume the same absolute numbers as with men. That means, if you slightly increase testosterone in women, I would say at first they have no negative effects. The problem is, if you administer exogenous testosterone, it's usually so high that, with the current dosage, it feminizes them, and that's why a gel is actually quite smart, but you have to consider that it disrupts the woman's hormonal balance, especially if you administer it exogenously. That means, for example, estrogen or various other hormones are disrupted. That's why it's actually smarter for women to start a few steps earlier in the synthesis, where the hormones are produced, and to support that, and then to see if they increase on their own. So, something more natural, if you will. That's a bioidentical hormone therapy, if you will, combined with biohacking, because there are also some peptides that can actually lead to the signaling substances for hormones being stimulated a bit better, and thereby a certain, yes, a certain hormone optimization also takes place. Of course, this has to be monitored, but it's more complicated for women. At least it seems more complicated at first glance, one can say. Okay, women are super complicated, as perhaps in other areas of life, and men seem relatively simple. Simpler to understand at first glance. Yes. Yes. And I've also heard that because women's hormonal balance fluctuates over a month, if you take a blood test, you always do it, I think on the 14th day of the cycle or something. You can't just randomly, as a man, you wake up in the morning, let's check testosterone, and that's how it is every morning, and it doesn't matter if you do it on Monday or Sunday, it's actually fine. For women, there are basically one or two days a month when you can take a blood test to optimize from this baseline value, right? Correct? Exactly. So, depending on what exactly you want to know, you have to at least know where you are, right? And some time points don't make sense. That's true. Okay. So, we have this, let's call it a miracle hormone, testosterone, which, unanimously, if we could increase it in small doses, both in men and women, makes life a bit better, and also the neutrally valued factors, like, for example, muscle or fat-free mass, it's good to have more of it. So, if you have more muscle than fat, that's generally good. And then you say, if we go above 20-30%, then we have to see who we're actually dealing with. And it's possible that even + 400% is good, depending on where you end up. And there is, however, a kind of ideal target value. What do you measure? Do you measure free testosterone or, in the best case, so what we are orienting ourselves by now, it will always be total testosterone if you want to determine a deficiency. Generally, you need more values, of course. Yes, that's clear. And at the latest, when you administer it, you also need a few values that you always have to observe simultaneously, right? But if you want to check testosterone now, you need total testosterone, free testosterone, maybe also free androgen index, estrogen for safety, and of course the signaling hormones LH FSH, so that's where it comes from, and possibly also prolactin, and so on, these are the minimum things, and of course a complete blood count, because if someone has high blood pressure, for example, or very thick blood, meaning hematocrit is high, or you see something there, then you have to consider whether you can still give them testosterone, because testosterone tends to thicken the blood because it causes more red blood cells to be produced. Mhm. Yes, so. That means, I've understood, testosterone, the more testosterone, the better. Then I take my blood test and see, okay, I'm now, I don't know, at 50% of the optimum, and then you would try to make these 50% into 100% of the optimum. And 100% is now, let's call it the longevity optimum, where you say, look, you only have positive effects. Um, and if we go higher, you have reinforcing effects, then you have even more muscle and so on, but then we have to see, because then you might have heart issues or something, then you get broader, but you pay a price for it. But it seems to be the case. I've heard, everything has a price. More testosterone has no price. Um, if you could conjure it, if you could conjure it to an optimal level, and if we could reach that, everything would be a bit better. Yes, so. Mhm. And if we have reached that, or rather, before we have reached it, we can achieve that traditionally with testosterone replacement therapy. So, we administer the hormone directly. It's not a medication, but it's a hormone produced by the body. You inject it, right? Yes, if you will, it's a synthetic replica of the body's own hormone, and you inject it. I would say we stick to injections for now. There's also the gel form, right? That's something that is unfortunately still sometimes done in Germany, but I would say, for most men or in general, it's not really practical, right? For people who are afraid of injections, it sounds good at first. That's why many do it. Over time, everyone wants to get away from it, at least most of them. And do you inject yourself or do you get injected by a doctor? Well, the romantic notion is that your doctor does it for you. Maybe that's why you're only supposed to come in every three months. That could be a reason. Realistically, the optimal form, probably enanthate, should ideally be administered twice a week. No doctor will do that for you. And that's why you do it yourself. So, in our project, we also teach people how to do it. So, there's video material, there are tutorials, there's help, we explain, we do, we do, and they can do it and do it. Where do you inject it? You can, wow, I won't say every muscle, you can choose many muscles. Ideally, a muscle with a large surface area, muscularly speaking, and few nerves or blood vessels running through it. Typically, the deltoid, the lateral part here, is often used. You inject yourself, I can't even, so you inject yourself, so to speak. There's a trick. So, if you do it like this, it won't work, of course. Yes, okay. But I can show you briefly. Oh, very easy. Look. Ah, okay. That's funny, the typical "steroid position" so to speak, and then comes Ah, okay. Yes, okay. But I wouldn't even consider the deltoid as a favorite. Of course, it's easy to do it yourself with it, but muscles like the thigh or gluteus are usually a bit easier to implement once you've understood how it works. Larger area, less risk, the right needle size is also crucial, and I know some theorists always scream, what about the sciatic nerve? I work with so many people in the medical field, and some tell me that in 30 years of injection administration, they have never experienced anyone hitting the sciatic nerve. What is the sciatic nerve? It's a nerve that runs along the back of the gluteus, and it's located a bit differently in everyone. That's why you're a bit afraid when you inject there that you might hit it and cause damage. That's one of the scary things that are often talked about, especially by people who have no involvement with it at all, right? By theorists. Exactly like they say, yes, if you inject yourself into the muscle and hit a blood vessel, you can die. Yes, but you would have to really inject the whole stuff into a critical blood vessel, and that simply doesn't happen. So, these are just things that don't happen, right? That's why it's always so easy to create fear of certain things, but that's what training is for, and that's why there are people or professionals who show you, and then something like that doesn't happen, and I've never experienced it either, and imagine, I'd say there are so many people who do it untrained, in the back room, in the gym, blindly. You never hear of anyone dying from a fat embolism or something like that. That means, if the fat were to enter the bloodstream and so on, that simply doesn't happen, right? So, these are all things that are unnecessary panic-mongering. Of course, right? With a Brazilian butt lift, that's exactly the risk of death, right? That the fat, the autologous fat that is injected, you inject it in the wrong place and you can die from it, right? In plain English. But we're talking about exorbitantly high amounts here, not about, I don't know, 0.25 ml of oil. That's a bit different, right? So, we have to always put it in perspective, and that's a problem I have in the entire biohacking area, not just with testosterone, but with everything that exists. There are people who look at something, have two or three theories about something, and even though they are professionals, they have zero evidence about it and just shout it out, and therefore find it critical. That's German Angst, that's Germany, and that's exactly why we are where we are, namely very far behind in this regard. That's why overseas they laugh at us, like, "German biohacking is a magnesium of sleep." Bye, right? And that's all fine, but it also needs a broader perspective, I think. That's very important, otherwise people don't move forward. And I'm aware that people can make incredible progress, both health-wise and for their own purposes, if they look beyond this narrow perspective. Definitely. And that brings us to the topic you started with. So, there are many people you know who do it. Before we get to that, let's go step by step. We're still on testosterone, so I understand. Injection. So, that means I have 50% of the optimal value, then you would say, look, balance testosterone, and do it in such a way that you reach 100% of the optimal value. Our 100%, right? Yes, exactly. Um, not the lab's, but there is, and testosterone has been extensively researched for 30, 40 years. You know relatively well what a good testosterone level is. What you inject is the hormone that is artificially produced. But it's not a medication, but it's your own hormone. I inject that, so to speak. I'm already doing it with my left hand. I'm not injecting it currently, but I find it naturally totally interesting. Surprise, surprise. So. Um, the disadvantage is that I have to inject myself, I learn that or can learn it. Aren't there insulin pens that make it easier, or do you really use a syringe? You are, you are well informed. That is actually our, I don't want to say unique selling point, because that has, that has definitely spread. I've gotten our doctors to agree that they like it too, and it's great for people because we actually only use insulin syringes, so those big brutes you know, those harpoons, they're not used here. Um, you have a very thin, so there are different forms of insulin syringes, there are the very tiny ones, with which you usually inject peptides, because you just need to get under the skin, and then there are a bit longer ones, and with those you can actually get very well into the muscle, and that's why we use them, it's pleasant, it barely pricks, it works wonderfully, you just need to know where to inject, and then it works, and then people are no longer so afraid of injections, because I can understand if someone jams such a thing into themselves, that looks so thick, as it's often done by doctors, um, that it's intimidating, and that it hurts for a few days afterward and is uncomfortable. No one wants that. So, that's fine. Yes, but an insulin pen, it's not like the needle shoots out of it, but the needle is, I've never held an insulin pen, I've only read about it. We need to differentiate. It's not an insulin pen. Okay, because an insulin pen has a much too small attachment. With an insulin pen, the attachment is so small, you don't even see it. So, you can use something like that for peptides, so for anything where you need to inject subcutaneously or intracutaneously, meaning into the fat, into the skin, somewhere there. Um, testosterone, it won't pass through there. You need a minimally thicker needle, but you can also administer testosterone subcutaneously, by the way. So, that's another hurdle we've removed for people, because a subcutaneous, meaning not into the muscle, but under the skin therapy with testosterone, even though it's oil, if you will, works. It just takes a bit longer for it to seep in and for the active ingredient to be released. But for anyone who is so extremely afraid of injections, that's a great thing, because they can usually overcome that more easily, to just push it under the skin, if you will. And with small doses, it works. With steroids, it won't work, so you'll get a lump at some point, and the skin will be irritated, and that won't work. Okay. Um, okay. That's the hormone, it's extensively researched. It's relatively clear that it works. In fact, I think since around the late 1950s. So, it's been researched for an extremely long time. Um, it's researched, you know it works. You also know what's in it. It's available everywhere. It's not complex to produce. Or so. You don't need any backroom stuff, as long as you find a good source. It's also available in the backroom, but it's also available in every pharmacy, they definitely have it in the basement, or at least that's how I imagine it, because it's a relatively common, normal hormone. Yes, I've been getting testosterone on prescription for a long time now, because I stopped using steroids and naturally had a deficiency. Accordingly, I've found that, well, I could have fixed my deficiency, but I find it more comfortable this way. And I've found that no matter where you go, testosterone is in stock. Everything else is more difficult. So, no matter what else you want, it's somehow more difficult, but testosterone is almost always in stock. There was a time recently when there was a shortage in all of Germany, but that was because a large company changed its carrier oils. Okay. So, we have testosterone. So, one way is to supply testosterone because you have too little, then you add a bit more. It's more or less the same substance, right? So, the disadvantage is that your own testosterone production stops, and I have to inject myself. I find both relatively unappealing. Um, then there are medications, but we're in the realm of medications that increase the body's own production. Mhm. Correct. And then, of course, I'd say, on the internet, if I type in testosterone booster, there are 3000 million things, but they probably don't work, or is there anything that works? Testosterone boosters are equivalent to the

People who say I boost your testosterone. Of course, there are such approaches. We have 100% reliable data, extremely much of it, that increasing your own testosterone within your physiological range has no benefits for muscle building or anything else. That means, whether you increase your testosterone, let's say, here is the range, right, you are somewhere in the middle. Mhm. From here to here brings nothing. Zero. From here to here brings a little bit. And here I would position the testoboosters. That means, if you have a deficiency, if the product is well-designed, it can actually, there are various substances that you can combine well, you can increase it by a few points. Will you get it into the normal range with that, no. With years of work and lifestyle intervention perhaps in combination is difficult. Very difficult, I would say. Okay. Yes. Um, so, but there are medications, real medications, not testoboosters, that work, but they are researched and there are um um there is, what is it called? One is enclomiphene and the other is called clomiphene, thermoxene, HCG. HCG, exactly. Um, these are things that you should normally get from a doctor. Yes, so there are actually now we are very, very deep into it, but I think testo is just the biggest topic and when I look at it, the more testo the better. Okay, how can I get testo? Yes, you can inject it. Yes, okay. You can inject it, you have to inject it your whole life. Unless you come back down complexly. Um, or one tries to optimize it, not, sorry, not optimize it naturally, but to stimulate your own production. Then you take medication and then there are different groups of medications or different medications. Is anything approved for that or is it all off-label? Exactly. So, if you try to increase testosterone with medication, first of all, what we need to understand is that the potency is not the same, because they are different receptors. You're talking about potency now. You don't mean sexual potency, but the effect. Good that you said that again, but both probably. Yes, both and probably even with certainty, because testosterone as a medication, testosterone stimulates the androgen receptor or doctor androgen receptor. That in turn accounts for potency in every respect. That means more muscle building and so on, you said testosterone as a mother gives medication, but testosterone is not a medication, but a hormone. Yes, but it is still a medication at that moment. So, if we inject testosterone, it is still an approved medication that you can get at the pharmacy. Ah, okay. That, okay, we have to classify that somehow. If you take an enclomiphene, for example, or we'll get to enclomiphene later, these are these SERMs, selective estrogen receptor modulators. Let's take, for example, and the best known is enclomiphene, it blocks your estrogen, if you will, at the signal, and thereby your body on its own, because estrogen is vital and testosterone is not, will say, we need estrogen from somewhere, so it produces testosterone, so that estrogen is made from testosterone, because that's how the male body actually makes estrogen. From testosterone. This is not a stimulation of the androgen receptor. This is a feedback loop that triggers an alarm signal, which is why you start producing natural testosterone again. This has very little to do with the stimulation of the androgen receptor and that's why you have all these wonder effects, if you will. You don't have them so noticeably, but you naturally have very good physiological testosterone. By the way, you might not want to take clomiphene. It's a bit side-effect intensive. But that means it's still something different. But if we continue, tamoxifen, perhaps a bit less aggressive. Clomiphene, for example, with high and long-term intake is also associated with, for example, a lot of mood swings, headaches, but even visual disturbances. Someone in our coaching back then applied because he combined tamoxifen and clomiphene due to an internet recommendation, forum recommendation, and he suffered lasting damage to his eyesight. So he still doesn't see everything 100% today, because these SERMs are dangerous, you have to say. Especially if you can't handle them and that's where enclomiphene comes in. Which is not approved here, of course. Enclomiphene is a component of clomiphene. There is suclomiphene and enclomiphene. Clomiphene consists of these two. If you isolate the enclomiphene, then you have relatively relaxed, selective effects. You still have this feedback loop somehow, because the receptor is occupied and that means, for example, something is not happening at the receptor right now. Accordingly, you still have good natural estrogen, which you need. But the receptor is tricked into thinking that nothing is happening. Accordingly, a feedback system has to be triggered, and you produce more testosterone, and then you have actually achieved everything. Your testosterone can reach a normal range, you feel better. Various studies have shown that it can even reach minimally higher physiological ranges. Two disadvantages. First, this effect, that of the testosterone, you usually don't have that. Next disadvantage, we observe, we don't have the long-term data yet, but what you observe in the studies is that the effect decreases over time, that the dose has to be increased successively, which is a bit annoying, regarding the whole thing. Accordingly, [sniffles] a good fix at first, right? But natural, if you want to call it natural, because it's already a strong modulation, right? Yes, for me, the word medication is something that bothers me a bit. If I inject testo, for me it's not a medication, because what do I want? Testo. What do I take for it? Testo, yes, it's not a medication in that sense, but it's still a synthetically replicated form. Yes, but that's why it's a medication. Yes, I understand that it might be legally so. But if I want X and get X, then that would be an exogenous form of the same thing that I have in my body. If I take an antibiotic, it's not a substance produced by my body, but it's some chemicals that make my body do something. So, and that would be these SERMs for me, so to speak, medications that modulate something in the body to get more testosterone out in the end. And you say there are better and worse ways. Mhm. And because I've dealt with this before, you know, um, I found that quite strange. So, there is clomiphene as a medication. Um, that is one of the medications that, if you say, okay, I don't want to inject testo at all, because I don't feel like dealing with injections and I don't feel like doing it my whole life, can't I take something that's simpler and where I can try it out. So, then there's clomiphene. Clomiphene is not approved for that at all, but clomiphene is actually a medication, if I'm correctly informed, that is approved for women as an estrogen modulator thing. No idea. Estrogen blocker, mostly for breast cancer or something like that. And it was found that if men take it, something is blocked, and then they get more testo. So, that's an effect. So, but this clomiphene, which you can buy at the pharmacy, and if you basically go to the doctor and negotiate with him, say look, I'd like some clomiphene, because I've read here that and your doctor might be awake, then he says, look, I'll prescribe it off-label for you. um it's common, things are prescribed off-label or not entirely common, but it's not like a doctor says, I don't know if there's any doctor who has never prescribed anything off-label, no, that's part of the game. Off-label means, hey, we have studies that said medication X helps for Y. Now we've found out, we don't have proper studies for it, but it's common to use it for something else. So, that's off-label. So. And the problem with this clomiphene is that it causes side effects, and then it was found that if you isolate a part of it, clomiphene consists of two parts, um, then it's this and this, one part causes the side effects and the other causes the effect, and if you isolate that, so that's how I understood it, please correct me if I'm wrong, then you basically only have the positive effect on testosterone, but you can keep your eyesight, which is really nice, and therefore it seems that in America, when you um they've stopped using clomiphene off-label, but they use enclomiphene, um, because it has fewer side effects but the same effect. But if I want the same thing in Germany, I can't go to a pharmacy and say, I'd like this enclomiphene, because the Americans do it. You also have clomiphene, that's the better one. Then the pharmacy says: "No, no, what do you want from me?" It doesn't exist, they say. "It doesn't exist." It doesn't exist here. Not just here, they say it doesn't exist at all. Okay. Uh, and then it has to be chemically synthesized. So, chemically it exists in reality, but in the catalog, in the pharmacy, it doesn't exist. Correct, and then you basically call your buddy who has a chemistry lab at home or who was just in America. That's the easier way. But a chemist could synthesize it. Uh, and then you get this SM, yes, this medication, so to speak, through some underworld channels, and then you take it more or less. So, and that's how it works in Germany. M, yes, exactly. So, in the USA too, the most common use of this is to do TRT with injections, but also to add enclomiphene because it keeps you a bit more fertile and keeps your testicle size normal, which I personally don't consider a real reason, because you can do that situationally if you need it for fertility. We do that too, by the way. So, we make people fertile again. It works very well, even on TRT. Um, but yes, most people do both, but there are also various proponents of clomiphene-only TRT, they exist in the USA too, and as I said, there are also people who are quite satisfied with it. Yes. Yes, the more the better. There are no disadvantages, so to speak. Uh, but now there are disadvantages. Namely, testicles get smaller. Uh, but that's not caused by more testosterone, but by exogenous administration, because the testicles no longer produce testosterone themselves. So. And if you administer it externally, then the testicles get smaller and sperm production decreases. That means if you want children, it's generally a difficult, difficult issue, so to speak, because you're reducing your own sperm and testosterone production. But that's not a side effect of too much testosterone, but a side effect of externally administered testosterone. Yes, of exogenous administration. It's simply that LH and FSH stop working, no longer dock at the testicles, and therefore the testicles stop working. I often get annoyed by the fact that, well, I don't understand why people always argue that it's an argument against testicles shrinking. I don't understand what advantage that has, what size the testicles are. [laughter] You don't know what you do with them or what they do, right? I once received a cool message. Someone said: "Hey, can we do something with the testicles?" Because sometimes I'm in the sauna with my buddies and it always looks weird. Then I thought: "Yeah, I don't know, I don't quite understand it, but there's a real danger, if you will. Theoretically, a testicular ascent, so that it slides up, could theoretically happen more easily." But that's not something that happens often in general, right? But otherwise, those things just have a cosmetic function. The fertility thing is true. However, you are still fertile, right? Only slightly. That's why people still end up with direct hits, more or less by accident. Ironically, those who don't want it somehow always do. And even bodybuilders on competition diets often do it. And so fertility is a different topic, because you have very, very few quality sperm, but you still have some, especially if your lifestyle is good, because it's largely lifestyle-dependent and you can regulate it relatively easily again. So, enclomiphene contributes to regulating them up again to some extent, even on testosterone, and two or three other medications can make it skyrocket, so that you can even have children relatively quickly, even on testosterone, faster than someone who probably does it without. We do that regularly. Okay, so in this whole testo game, there's exogenous testo, which you just inject and administer, and then there's a group of medications, but they are actually relatively poorly researched or not poorly researched, but they are poorly researched and it's not easy to get them. Yes, if you know that clomiphene has the disadvantage that you go blind, you can yes, or visual impairment, I think it's officially called, but visual impairment is pretty bad. So, that's not just, that's also very real if you suddenly can't drive anymore and can't walk through the door because you can't find it. That's just annoying. Okay, but that's sort of the cornerstone in this biohacking world, as I understand it. M, you would probably, correct me if I'm wrong, if I came to you and said, look Mike, what can I do to have a better life, you would, if you could do one thing, optimize testosterone, correct? And then and then look at testosterone, fat, sugar, that and sleep. And sleep. Mhm. So, if we have testosterone at an optimal level, optimum is also a bit subjective, presumably, because if I really like to pump, my optimum level might be 20% 30% higher than the optimum of someone who walks down the street and says, I just want to be awake, have no brain fog, and sleep properly. Mm. But there is a natural level where we are on average, and then there's an optimum level. How far are we from that? So, we have more disruptive factors for testosterone today than ever before. That's why perhaps this view, which many share, that we have the least testosterone today, right, compared to the past and so on. You can't say that, but we have more disruptive factors, I'd agree with that, and therefore I would say, so today people's blood work, all the blood work we get, is not optimal. So, even if I randomly check people who are in normal coaching, they rarely have good testosterone levels. This is due to increased stress levels, right? Nobody finishes work on time anymore. Many have two jobs, everything is getting more expensive. And you can see that in people. What percentage is that? I can't say, but if we have testosterone, our reference range, I'll go back to that. It's a bit shifted anyway. That means even if you're in the middle, you might actually be further back, right? And the people are always at the lower end of the reference. I know almost no one with super testosterone levels. Therefore, I would say most people are something like 30 to 50% away from what they should have. And I even assume they won't achieve that with natural optimizations for the aforementioned reasons of disruptive factors we have today. Because you have a life, you might have to sleep little, you might have to work longer, and who really eats properly? Who pays attention to nutrition, enough healthy micronutrients, supplements, all those things? Nobody does. And stress is higher today than it has ever been. And that's where the biohacking approach comes from, saying, okay, in an optimal world, where I'm wrapped in cotton wool, I could have perfect testosterone again in two years, and who works then? So, can't I just maintain my workload and function better? Can't I just sleep better? Can't I just withstand more stress, and I know this is a destructive cycle we're getting into, and then the question is, where is the end at some point, right? But everyone has to decide that for themselves, and I also warn about such things. I say, hey, I don't know, maybe we're buying a bit too much productivity right now, and in the long run, it will cost you something, don't do it, right? But if it's just about testosterone, I say most people can't do that naturally or improve it without their life as it is right now. On a health level, it would be a gain. But on a productivity level, they would probably have to save a lot, and I don't think that's possible. Mhm. That means testo is the basis for everything else that follows. So, let's assume I'm at 50%, then we discuss two, what to do to get it to 100% and where my 100% is. Yes, so if we take a very brief excursion into doping, if the backyard doper, how much higher is that than your optimal value? 300-400% it starts. That's roughly where it begins. That [clears throat] means if I, I think free testo in the optimal range would be 500 plus minus, so 500, let's take total testo, it's maybe a bit easier, if you take a typical scale, we have a scale that goes from 3 to, let's say, up to nine or ten, and then there's the scale that goes all the way to the end, if you, for example, it goes beyond the reference and then to the end, and then it says, for example, 15, and it goes beyond that, then it just says, for example, 15 plus, you can't get more, and that's where they all are. That means they are somewhere around this 15 plus. Okay, but so that I have an idea, they are not 20% above optimum, not 30%, but 300% above optimum. Yes, easily. Okay. That means what is considered, because we had doping and biohacking, which look so similar, because both the biohacker injects testo, the doper injects testo. So, the doper does three to four times as much as the biohacker. Yes, and the bodybuilder sometimes does, we're talking about dosages that you can't imagine, right? So, it's really 4 5 6 7 8 900% I don't know. So, 900%, you have to imagine, if someone is at 125 mg, which we're talking about, for TRT, it's not uncommon for people to inject 750 to 1000 mg of testosterone alone per week, and then there's the rest. It's very difficult to define where a bodybuilder ends up sometimes, right? And that's why I say, from the moment you start bodybuilding, you put the goal, the mission, above your health and you try to do damage control as best you can. And nowadays, you can do that better than ever before. Nevertheless, it remains a risk, and most bodybuilders die today because they ignore the signals, because it's relatively difficult to die from steroids. You have to make a lot of effort and do it very consistently for a long time and ignore everything your body tells you, and then it happens. And that's why there are big differences, very, very big ones. And what bothers me, I'm noticing a lot on LinkedIn, is that experts, when you talk about TRT, even about someone who takes a bit more than TRT, they throw that back at you. So, we are so far away, you can't even look that far, that's how far away it is. Especially, I don't know, we're talking about decades that lie between polypharmacy, i.e., mixed consumption of all sorts of things in exorbitant amounts, and the ignorance of everything your body throws at you, and therefore you can't equate that. That's why testosterone is not equal to testosterone. Yes, crazy. Yes, it's a bit like, I don't know, if one brushes their teeth and the next one uses baking soda every day and I don't know, their teeth have already dissolved, but they are nice and white. Yes, it doesn't seem to be the same, not only not the same, but they are far apart, even though it's basically more of the same substance. So, from that perspective, it's all very, very similar. Okay, if we've now reached the testo optimum, however we managed that, right, then the question arises, you already said it earlier, what else can be done? Uh, usually it doesn't stop there, uh, or in an ideal world, it doesn't stop there. What can be done from here? What's always a big point, it almost always comes at the same time, is of course, how can I control my weight a bit? That's it, I think that's the basic pillars of biohacking, also a bit like, how can I just look good and still master my everyday life, ideally with health benefits, right? And indeed, for a while now in biohacking, all these GLP1 receptor agonists, so for example, semaglutide or Mounjaro as tirzepatide, have been in vogue. Now there's something new. It's called retatrutide, if you will. Retatrutide GLP3, if you will. Here's another receptor involved, and the sensation here is, it suppresses your hunger. You have very little hunger and it burns more fat at the same time, without you having to do anything. This fat ideally comes, as is the case here, from your liver fat, which is burned. So, the calories you burn come from your liver fat. Accordingly, it also makes your liver healthier, and you have more subjectively noticeable energy from it. And therefore, it makes you metabolically healthier, you have less hunger, it's easier for you to maintain your figure. That's what's often taken. And then it usually goes in the direction of sleep, for example. What can I take to sleep better, to increase REM and deep sleep, for example? The approach is often what I also consistently try to pursue. How do I manage to achieve my REM and deep sleep values with relatively little sleep time, as you do with 8 hours, for example, right, which I sometimes manage quite well with 5.5 to 6 hours. Um, that means you would theoretically, if you could maintain that long-term, have a 2-hour competitive advantage over any competitors, rivals, whatever you want to call them. And these are the approaches that are pursued, right? One simply wants the best possible sleep in the time they already have, healthy through and through. The other tries to achieve the same effectiveness with a bit less sleep. Healthy at first, but in the long run, you have to look at the wear and tear parameters, right? So, we have relatively much. The next one wants to burn fat, get more out of their training, burn more fat with less training. What can I take for that? What can I add? And then there are people who say, how can I be even more focused while working? I always drift off. I always end up somewhere else after a while. What can I do about it? How can I remember more? How can I improve my cognitive abilities in the long term and absorb and retain an incredible amount of information in certain moments when I need it. So, cognitive biohacking too. All of these, it goes in many other directions, combine to form an area where you say, I take this for that, I take that for that, I take that for that. Eventually, you become a super-optimized human being who functions well at every corner. Yes, and that's where we directly enter the borderline of that. So, we have the testo, that's a bit like the apple. So, if I eat an apple, you can say, yes, there's also a bit of sugar in it, right? But generally, eating an apple is always good. Unless you're on a severe calorie deficit, then an additional apple can tip you over. So, but generally, an apple is good. Yes, so testo too, we've discussed, there are some side effects when you administer it externally, except for the needle insertion. Yes, but generally it seems that you can take it until the end of your life, or how long do you take it? I would say, the longer you take it, the older you get, the better it is for you, because the decline is held back more, right? All the other physiological processes continue to decline, and testosterone keeps you alive a bit. So, the older you are, the more it benefits you, you can really say that. Okay, so that's something where you don't say, okay, we have to be careful that it doesn't cause long-term damage, so we have to stop it at some point, but it's, if you decide on it, it's okay. And when you die, that's the day before, you take the last injection, so to speak. That's it, and you will subjectively have a better life and can be relaxed. Um, you might have more drive, you're not necessarily just more productive, but you simply have a better quality of life. So, that can be said relatively clearly. So. And now we come into an area where the border to becoming a machine is quite touched upon. If we stay in the weight area first, so Osemic works, that seems to be relatively clear. So, these are people I see, and I observe them, so I've never in my life seen so many people who have undergone such drastic transformations, but they say, before, when someone was so drastically transformed, it was like, hey, dude, you look amazing, and everyone was enthusiastic, cheered. Yes, well, I changed my whole life, and today everyone says, "Thank you, next topic." Because I've injected something, and it seems to work relatively easily. So, then they usually lose fat and muscle mass, because most people don't train or do protein and so on. Uh, so, it's a bit of a cheat, but for someone who goes to the gym and optimizes themselves properly, it's actually also a um not necessarily an Osem, but Osem could also be a kind of doping agent, because it suppresses appetite, I believe. Uh, in principle, that's what it does, and the other successors do even more than just suppress my appetite, they also increase fat burning. Exactly. So, one of them, that's the newest one, which is currently in phase 3 of clinical trials. The phase 2 data have been published and are among the most groundbreaking seen, because a weight reduction of approximately 24.2% has been achieved in a very short time. That's something that previously only surgical interventions could achieve. So, such effects have never existed before. And in the sub-analysis of type 2 diabetics with fatty liver, it was seen that 89% of all fatty livers were completely neutralized in that period. You have to imagine that. The HbA1c value, i.e., the long-term blood sugar, has dropped by 2%, so that people can put it into perspective. 2% is the deciding factor between diabetes or not, easily. So, that means someone who really has an HbA1c value of, let's say, seven, which is really dangerous, can go down to five, and five is healthy. Accordingly, all these markers that have been observed are groundbreaking, and this will most likely, it won't take long, it will come onto the market relatively soon. Similar to enclomiphene, there are already ways to obtain it, and it is being diligently used, especially in the biohacking community, because here we can estimate the side effect profile relatively well. We have the studies that are actually exactly the same as with the GLP1 receptor agonists. They have exactly the same side effects. In the end, it's the same for all of them. You have some gastrointestinal side effects, right? That means the more you take, the more nauseous you might feel, or you get constipated. But the big problem with these studies is that the dose was increased too quickly, and doctors like to do that, and that's why people have these side effects. You only need a very small amount of it. The rest you do best with a bit of discipline. That would be good, because then you can actually eat the right thing, not be malnourished, but not have so much hunger, burn fat better, your liver is healthier, and in the long term, you also have reliably healthy blood sugar. And here I see a big biohacking benefit with Osemic and the previous things. Yes, but what also needs to be mentioned is that we can actively help people with it. So, in our coaching, it's like this, with overweight people, we first counteract with these medications and then can address the testosterone deficiency. And that helps, because many people can't change their lives overnight. And I believe that these GLP1 receptor agonists give you a kind of, let's just say, kickstart, a deadline during which your hunger is taken away, and then you have time to establish a healthy routine in the form of training and nutrition. If you don't manage it, hence we have this rebound data, it exists. There are graphs that show how quickly they regain their weight when they stop. Yes, but that distinguishes testo from these GLP1 blockers. Um, that they are agonists, sorry, GLP1 agonists, they don't block. Oh, sorry. Um, we actually don't know what happens if you take it for 30 years. Yes and no, um, the first GLP1 research is extremely old. I think from the 80s or 90s, I don't know exactly, because this active ingredient was actually originally taken from a reptile, called a Gila monster or something, because it releases this active ingredient to enemies so that it's not eaten. That's been going on for an extremely long time. So, we've understood the GLP1 receptor signaling pathway for a very long time, and it's been a damn long time since the first medication came onto the market. Scientifically speaking, it's still young. So, long-term studies are, I don't know, 50, 60 upwards, but then again, the question is, if someone starts taking it at 20, and we know it's safe for 50 years, and what about after that? Do you care at 70, right? So, do you understand what I mean? That's your whole life, and therefore GLP, so I'd say OSEMPIC and so on.

has been researched for a very long time, these combinations, yes, with GP now, for example, a game, so Monjaro and the brand new GLP3, that is young, very, very young, but it is, I would say, very well predictable from the signaling pathways, right? That means, one can assess very well, what does it do? That means, the difficulty is, so to speak, uh, in this area, um, to understand, okay, how much data do we have? Ah, we don't have that much data yet, but the data we have looks mega. Mhm. So and then, okay, maybe there are long-term damages, but it looks so much better at first glance. A bit like Enclomiphene now, for example. It looks better at first glance. We cannot prove it over 50 years, but what if one were a doctor now, would one ask oneself an ethical question? Is it still ethical to give the patient the old medication, of which I know that it has a certain side effect profile or simply works less well, or is it more ethical? to give the newer one, of which I don't know at all what will happen in 30, 40 years. But it seems to me to be clearly better based on the things we already know. And that is then the decision that one has to make for oneself as a biohacker. What do we already know? Should we wait another 2 or 3 years, but Mew, that's all a competition. The others are already taking the latest, coolest shit, and they're already burning fat in parallel, and I'm just having my appetite, uh, uh, so to speak, curbed. So I want the latest, latest, latest too. But if we think that through consistently, then everyone wants the latest, because the latest is usually better, and sooner or later, the latest will be really shitty. Mhm. So, because, if I understand correctly, one sees research, so a study apparently works like this: I say, I'm doing a study, and I'm regularly publishing data on it. E, pay attention, and we took this chemical substance. This chemical substance, it has a patent or could be patented at some point, but while the study is running, it's not yet patented. That means, I can assemble this substance in my chemistry basement, which is currently being used live in the study, and it will probably tend to work for me as in the study, but I don't know what will happen with it in the medium to long term, and that is, so to speak, what the biohacking community does. It's, so to speak, live on what are the latest studies, what is happening at 9 AM on Monday, what is Professor XYZ currently doing, and let's quickly synthesize that, I'll blast that into myself too. Whereas, I would say, on the completely other, other side of the spectrum. The doctor says, I finished my medical studies in 1985, and back then it was said that counting calories, for example, is nonsense, you only have to count fat points. Um, then yes, you're laughing. It's a true story. Um, and the two then speak to each other on LinkedIn, so to speak, and one is, so to speak, totally behind, so really just 30 years, and is behind in terms of specialization, in the sense that doctors are not good for health, but good for diseases. And the next one says, so on your side now, hey, pay attention, we already know that this works. This works. Here are my 100 clients, they are all ripped, they are all strong. Um, you can take it, it's not dangerous. And I am now, so to speak, as a customer, and then I go to my doctor and say, the doctor says, Mike is a criminal. Uh, and Mike says, in essence, the doctor, I don't know, he's also a criminal because he should actually know better, but doesn't know better. So, and we move on this spectrum. Correct. Yes, so clearly, excellently presented in itself. Yes. So, and now I, as a poor customer/patient, I hear such a story from you and think, boy, I need more of that, so do you have that with you? So, can we take a short break now, because all of that sounds good at first glance too. Yes, exactly, right? That it's like heroin or something. Yes, but that's, we are in such a, that's a doping area, so we are in such a doping area, and you say: "Hey, if you take a little bit of the doping agent, it gets better." It's a bit like drugs. Yes, it has that character. It definitely has that character. Sure, we have WHO classifications for when something is a drug or not, right? So steroids are not included, according to the official classification, but we naturally have a different form of dependence, and um, everything can be an addiction, if you will. Training can also be an addiction, and definitely. So I also experience people in coaching who fall into the trap, very, very much, right? One could, I think, from an outsider's perspective, if one doesn't know the topic, then one has no idea, then almost everyone has a trap, right? Someone goes to train regularly, you say they are addicted. Yes, that means, I always find it a bit difficult to classify it like that, but fundamentally, yes, you get into such a vortex, and I would rather see it as a continuous opening of new possibilities, which is seen as an addiction or trap by outsiders, right? Because you dive deeper and deeper, then you see longevity effects here, then you see, okay, I can sleep better, then you see, okay, I can burn fat better. For you, that's normal, for an outsider, they get a shock when they see what you take in the morning, right? But and that's the point, that's where I differentiate from the drug addict, because with them, you also get a shock when you see what they take in the morning. Um, you are healthy, and therefore, what you said is great, that one says, okay, we don't have much data on some things because they are new. In the biohacking space, I would clearly subdivide again, there are few things that one simply takes, even though one knows nothing about them, because most things that are taken have a history and are the latest development from this history. That means, from past studies and decades, one knows relatively well what these things do, and one is constantly working to optimize it further. One means, that means one was somehow already in conformity with the previous things and knows, now it's even better. And then one can say, it is quite unlikely that it will suddenly do something completely different. It is quite unlikely. But maybe [sniff] a current story. There is a medication that is currently being developed, which is also supposed to enable muscle building without moving. It is a monoclonal antibody, a myostatin inhibitor, and Eli Lilly, so it is a very large pharmaceutical company, has already invested around 50 to 100 million in it, has been in Phase 1 of clinical trials, has worked great. That means, these are the first studies on humans. Now comes Phase 2, then only Phase 3, then it will be approved. Until then, it's about a billion or so, right? In Phase 2, there was recently the official announcement. Eli Lilly is stopping research. Nobody knows why. So this medication, which gives you muscles while you do nothing, or counteracts muscle loss and really builds effective muscle mass. The counterpart to Osempos, if you will, where you don't have to do anything anymore at some point. That was suddenly just stopped. Nobody communicates why. Now we have to wait and see. What could be the reason? But I bet the first underground labs have already rubbed their hands together and said, how on earth can we actually build this? But that won't be that easy. So, that means, there are of course always surprises and there are unpredictable stories, but one must also say that the history of antibodies against myostatin is difficult anyway, but one has never really managed to do that in humans, that myostatin is a protein for uncontrolled muscle growth. The holy grail seems to be, especially for people, now, we are talking only about health first, before the bodybuilder comes and says, look, right? So first of all, it's about people with incredibly cachectic conditions, so tissue wasting, diseases, whatever, that they get something that can inhibit all of this, so counteract it, and that's what they're researching, and so far it has never worked via the myostatin pathway, only in animals. We know some of these images of the super muscular dogs or whatever they are, or even mice sometimes. There are shocking images from studies. In humans, it's been quite difficult so far, especially since one must also consider that the heart would also be affected, right, with striated muscle, with a component. Accordingly, perhaps that's why the whole thing was stopped, I don't know, but that means, there are still surprises, and I personally think, in biohacking, everyone is responsible for informing themselves. You can't just blindly take things, and if you don't know it yourself, then inform yourself, and ideally, I wouldn't necessarily say in internet forums or something like that. Go to people you feel know. And if I don't, I don't have to. But then read studies yourself. Do it yourself. And if you are of the opinion that you don't have time for that, don't feel like it, pay someone who can do it, or leave it. Just leave it, because that would be my take on the matter. Yes, you just said in a side note, um, Lilly researches or has researched this muscle medication. That such a medication costs a billion to bring to market. They then invested 150 or 50 or 100 million in it and then stopped. Uh, that means, world pharma works with diseases. That means, I have a disease, such as age-related muscle loss, there are many, many old people. If I manage to, or I look at the disease catalog ICD10 and look, okay, what diseases are there and how many people are affected by them, can I make money with it? Very selfishly, but rationally economically. Okay. Um, people lose muscles, then they fall, break their bones. I could approve a medication that combats this muscle loss. I'll do a study. So. And the biohacking world comes along and says, pay attention, what the pharma company wants is to heal old people so that they don't break their bones when they fall, so that there's a little more muscle. So, there is also the economic market for the pharma company. But the biohackers say, wait a minute, if the 80-year-old grandma has muscle growth or possibly no loss, and I take three times as much and train in parallel, what does that do to my muscles, and then the studies are published, and then I see, okay, it works great for them. And then you just talked about underground labs. That's not patented yet, is it? It's patented at the end of the approval process. I think a patent is usually filed before the first phase of clinical studies, because a company secures it before investing so much money. So usually just on the side. Okay. So. And a patent is public, right? So it says what they put in there, because otherwise you can't hold the patent. Exactly. Right. And these underground labs and the biohacking community are, so to speak, like pirates. They download the patent, say: "Pay attention, then I'll cook my own little stew." Um, and I'm not actually allowed to do that. I do it anyway, and it works, and then we are exactly in this space where there is actually no pharmacological interest in bodybuilders getting bigger faster. So that will never be covered by health insurance. If I say, I feel so weak and therefore I am depressed. Yes, take the medication, then you'll get bigger and your life will be better. So, that's, so to speak, that only happens in the biohacking community or the bodybuilding community, and they also don't have a billion for the approval of such medications. So there seem to be these substances, about which one knows something from some studies, but which are perhaps not intended to make bodybuilders stronger, but to prevent elderly women from breaking their bones. So, and there one absorbs the know-how from this pharma world and makes a pirated copy of the medication essentially. Mhm. Right. And that applies to medications, and then there is, you have this, in essence, also Osempos, Empic is a medication for obesity, obesity disease, ICD10, great. If I take it, if I just want to do a deficit phase, it could also work. So it's, so to speak, an off-label private use, I call it that. And then there is this group of peptides. And peptides are not medications, but are, so to speak, amino acids that are not complete, if I understood correctly, and they then send some signals in the body, such as fat burning, or is that wrong? Similar. So first of all, GLP1 receptor agonists like semaglutide are also peptides. They are peptides. Many peptides are actually medications now. Ah, okay. Um, insulin is a peptide. Um, HGH, so growth hormones. Well, that's actually already, that's actually already a protein, with so many amino acids. Accordingly, one must imagine, peptides are chains of amino acids. Creatine is a peptide, if you will, a tripeptide, or various others. Peptides are chains of amino acids. These amino acids, so our body functions through amino acids, proteins, and everything else, depending on the chain and arrangement, how the amino acids are positioned and bonded to various other substances, they send signals to your body, and these peptides are created, or rather, the reverse is true, they exist in the body, all these peptides already exist. They perform certain tasks in our body, and what one tries to do is to replicate them, so that one can compensate for a possible deficiency of these peptides in the body. For example, BPC [clears throat] 157, I think many people can relate to that now. That is a peptide that ensures that you, how to say it? You heal faster, right? If you have an inflammation or an injury, something, then with BPC 157, the inflammation goes away faster, a wound closes faster. It also has osteogenic effects, it can also ensure that your bones heal faster in case of a fracture, and BPC 157 is from our stomach juices, so from the stomach acids, actually, if you will, and it exists there, and because it was seen at some point that BPC 157 triggers certain effects in the body that ensure, for example, that wounds close faster, inflammation subsides, and so on. One looked at some point, can't this be made pharmacologically accessible, and then they did that, and started conducting tests, and therefore there are, so to BPC 157, I saw about 375 studies in a video, for example, on animals. Um, on humans, there are only two. They are not good, one must say, because there was apparently no money for it, and they are really bad. But they both have good results, that Moment Moment. So a bad study with good results in the sense of, um, it's not double-blind, peer-reviewed, with 10,000 people. Yes, but the results seem good. I'll give you an example. Um, so this is really the study BPC 157. You have women with bladder pain syndrome. Only 12 participants, which is not a lot, but they are humans, they are women, they have the so-called bladder pain syndrome, they have chronic pain, and any medication has not worked in the past. They reported, I want to do this test. They were administered a single dose of 10 mg BPC 157, which is a very high dose, by the way. It's a lot, and the problem with this study is, I'll tell it to the end, then I'll tell you. At the end, the women were asked about symptoms. They had pain for ages, 10 mg BPC 157, and 10 out of 12 reported that 100% of the pain had completely disappeared. Two out of 12 said, 80%. So actually, everyone said the pain had disappeared. What is the problem? No examinations were done to see what happens in the body. It was simply done using a questionnaire. That means, I give you something, and do you feel better? You say yes. Actually, I don't know, I ask you, how do you interpret the result? I interpret it, on the one hand, that it works, but that something like this is called a study, I find that really ironic. So, if I now invite ten people, say, take this, do you feel better now? And then they say, yes, yes, it's going well. And I say, so pay attention, I did a study. Yes, so, it's not quite like that, right? It's difficult. Therefore, of course, one must say, all of them had this bladder pain syndrome beforehand and stated that nothing had helped. It says something, but that's a bit of the tragedy of studies that don't get proper funding, right? There was once one where BPC 157 and a similar peptide, TB500, were administered for knee pain. Um, that was one of the worst studies, I think, because a year later they called the people and asked, and how was it? Is it gone by now? And they all said, yes, it's better, but what do you want with that? In contrast, the preclinical studies, so those are exclusively on animals, are very clean. So with them, one has incredibly good results, actually all positive, and there one saw that BPC 157 actually does exactly that in all animals, regardless of which animal was taken and regardless of the type of trauma, from burns to brain trauma, so really dropping weights on the head and then looking at BPC, how fast it heals and so on, up to wounds of all kinds. So everything heals faster, one can see, right? That's the problem with the whole thing, animals are not humans, and that's where we stop, right? Where do the efforts come from? Where does the funding come from, when will there be really decent studies? But that's the peptide space. A peptide keeps coming through. A good example is Thymosin Alpha 1. I took that back then for my immunodeficiency out of desperation. And that's how many people turn to biohacking, because I had an immunodeficiency back then after I stopped using steroids. I was healthy the whole time. I was doing great. Maybe I just suppressed my cortisol and everything so relentlessly that my body just worked. When I went to the cardiologist and found out I was healthy, I was so shocked that I briefly considered, now more than ever. And then I thought, no, man, you're stopping now. It's enough. You're only doing TRT now. You're out, because I asked the doctor three times in disbelief, are you sure I don't have left ventricular hypertrophy? Not anything, echo, EKG, everything done. He says, "No, you have the heart of an endurance athlete." Then I said, okay, for me, I'm out now. I still remember saying that out loud. He said, well, maybe that's a good idea. So. And then, three, four weeks later, it started. To be fair, at that time, the corona wave was going on and so on. It hit me so hard. I was gone for four weeks, then it started again, and immediately again after a short time, four weeks gone. Um, actually, the tests were negative, right? One can ask oneself, whatever that was. And the tests were not always reliable either. The problem is, I haven't gotten healthy since. Everything I've tried hasn't worked. Everything within my knowledge hasn't worked. Doctors were clueless, didn't help me, and didn't recognize long COVID either. I had purely from the symptoms, for myself, concluded that it must be that. Suddenly I come across studies, videos about a peptide called Thymosin Alpha 1, which is used for severe COVID courses, and is an approved medication in the USA, as a so-called Sedexin, that's what it's called there. And it's approved as an orphan drug. An orphan drug is a medication that you can only use for diseases that have about 200,000 incidents per year, which are very severe, right? It's like a trial, right? So it's starting soon. We can already test it on people for whom it's already difficult anyway. Among other things, for DiGeorge syndrome, meaning people have no thymus gland, therefore no immune defense. Thymosin Alpha 1 still creates one, because it does exactly that in the body. I found that fascinating. I had really tried everything before. After Thymosin Alpha 1, it actually got better. And that was the first time for me where I thought, hey, we're not just talking about a little wound healing anymore, we're not talking about a little sleep, we're really talking about my health, I was almost no longer able to train, so for a while I looked like a wet rag, and I still made training content. Yes, people still bought it from me. Everything's cool. I also learned during that time that I am not just my body, which I found great somehow in retrospect, but I got out of it because of it, and since then we've been working with it in coaching, and there are many recognized doctors in the USA who work with it and talk about it openly, also on the Uberman podcast and so on, and they swear by it, and accordingly, in coaching, we have had extremely many success stories since we started working with it, of people who couldn't get back up before, for various reasons. Then we go back towards biohacking. If you get sick today, you can't afford it. High-dose Thymosin Alpha 1. In two days, you're fit again, no matter what you have. It can work, but it doesn't have to. Yes, so that means, there is of course also this potential for abuse again, but that's where we are, that's biohacking, right? But that's just one example that many of them are already medications. And I can give you many other examples. One has just been approved again for mitochondrial dysfunction, so for a disorder of your mitochondria, a cell disorder that can lead to cancer or all sorts of things in the long term, and a peptide called SS31 has just been approved by the FDA to fix this disorder. So that happens regularly, that they somehow come through, and these peptides become medications. Okay. Um, there is, so to speak, the fitness scene, which says, we want to take as few medications as possible. I don't even go to the doctor, because they only prescribe me medications anyway, that's stupid. And you come to a realization and say, yes, let's take more medications. Um, because they are great. But in different dosages for different things. I would differentiate and say, it's great that you're bringing that up. Let's look at the efficacy profile of ibuprofen or paracetamol and so on. Not for nothing were many liver-detoxifying substances tested on paracetamol poisoning. We have medications that everyone can access, which are incredibly toxic. Ibuprofen is nephrotoxic, hepatotoxic, paracetamol is extremely hepatotoxic. Anyone can take that. And so our previous approaches are also a bit difficult, that you get cortisone injected into your joint for an injury, which can demonstrably damage the joint. And there I say, that's where I differentiate from you and say, those are medications. And the others are, even though some of them are already medications, peptides. Peptides offer the hope of regulating the whole thing in a more elegant way in the future. And that's why I say, you're right, but this group of medications, in my opinion, is health-promoting, rather than just putting a band-aid on it or even making it worse later through other means. That's why I'm so into this peptide topic, because the development of a peptide always involves saying, I enter the body and see who needs help, may I join, I'm coming. A steroid, for example, comes in and says: "Who is not working here? Get lost, I don't need you, I'll do it now. I don't care what happens now." So, right? And medications are completely different. They say, here comes the cleanup crew, everything that doesn't work, put a band-aid on it, destroy it, get rid of it, bye. And that always has consequences. That means, we have not yet found the optimum, and peptides seem to be closer, but here, and this is because everyone will say it, and it's true, many of them are not yet approved, long-term data is missing. It seems so, I find it plausible when you look at the studies. BPC 157 was first synthesized in 1973. Since then, every study has been positive. And that's the case with many medications or peptides. So we've known for a very long time that they work. They just haven't really made it through as medications yet, but we also see that with Thymosin Alpha 1, SS31. It just takes an incredibly long time to get them so safe that even the FDA, which is perhaps a bit more relaxed than Germany, says: "Come on, let's try it." So until it comes, until Thymosin Alpha 1 is even discussed here, forget it. And then I ask you, if you are in a situation where you feel that your immune system is completely letting you down and nothing helps, and then you see that in another country I can get it, but not here. What are your thoughts on that? Yes, give it to me, right? [laughter] Give it to me. But so, I mean, if I have a big problem, that's one thing, if I have a problem and this problem drastically limits my life, what can I do about it? So, and then I find this peptide, and then I take it, and then I feel good. That's different from when I go and say, okay, what's there to make it even better? And I blast myself with 17 peptides that no human has ever taken together. Um, but I say these 17 studies, they seem to somehow, it sounds good, I'll blast it all in, because then I can be faster, higher, tendentially, I'll say these highly stressed people, they always have a profile of relatively poor self-perception. So, it's just, I'm somehow too tired after working 18 hours. So. Yes, that too. Possibly you are also, I don't know, depressed, dazed, you don't have it. Typical Type 1 personality, so, these very, very aggressive, stressed, very, very always in there. Exactly. And if you ask them how they are, they say, good, or they have to, it's the best answer. Yes, but at the moment when one allows for greater sensitivity, so then you start on a sensitive level. Okay, we can fine-tune a bit here, and then you think, these are all positive effects, and you don't know the negative effects. That's one thing. But the positive ones, they are real, and if I have more muscle, need less sleep, am more satisfied, then it's all real. But one also knows, for example, that testo, for example, um, um, makes cancer cells grow stronger too. So I have, for example, at least I don't think it does. No. Uh, I had growth hormone yesterday, the day before yesterday, I spoke with a guest, 85, who has prostate cancer, and he is being treated palliatively with a testosterone blocker. Aha. So. Because the cancer shouldn't progress somehow, I thought. Interesting. That's more complicated. Okay. That's because the prostate temporarily hypertrophies, meaning it gets thicker, or hyperplasies, when androgens are involved. And that, in turn, would be absolutely contraindicated in this case. So it shouldn't happen. But that doesn't mean that testosterone causes prostate cancer. It's actually been disproven. So accordingly, if you already have prostate cancer, it's still not that simple, because we often discuss this topic with doctors. Um, but it's not that testosterone causes cancer or prostate cancer. With growth hormones, we have to talk about something else. Here, too, it's more that these signaling pathways for TGF beta and whatever they're called are tumor suppressors in the early stage. So first, they hold back, but if the tumor is already there, then they promote it, because in a tumor, there's nothing else but a parasite, if you will. It establishes itself, suddenly iron is a problem. Suddenly glucose is a problem. Everything you do that is actually good is suddenly problematic for the tumor. Accordingly, growth factors that are actually good for you are naturally good for the tumor. That makes sense. That's also logical. An interesting food for thought here. There are a few small animal studies on mice in which it was found that the administration of BPC 157 led to angiogenesis, which is the formation of blood vessels from existing blood vessels, blood supply, nutrient supply, which actually leads to healing, being diverted away from the tumor. They don't know why yet. Further research is needed, but another study on GHKcu, which is a similar peptide, could provide an answer. It was found that GHKcu triggers a so-called gene resetting. It reduces inflammatory genes that are upregulated when you have cancer, for example. They are simply reset, and this was tested in a cell model for a disease called COPD, Chronic Obstructive Pulmonary Disease, a lung disease, and the disease could be reversed by resetting the genes through GHKcu, and it is suspected that BPC 157 does something similar with inflammatory genes, and therefore the tumor formation, or this supply, which is now supposed to be so beneficial for the tumor, was diverted in this case. This is purely experimental, it means nothing, but I'm just saying that because these are damn interesting stories, you just have to listen to them, they are happening. Everyone can do what they want with it. That's why I'm not saying, take GHKcu for cancer, for God's sake. I'm just saying, all of this exists. That's exactly what exists. And then there are, um, small studies, possibly animal studies, let's call them anecdotal studies. If I now have 12 participants and ask, are you feeling better? And they say, yes, that's, uh, it's almost like a story from the garden of Eden, but they are two studies. Um, yes, there you have, so to speak, if you treat ten people, or if you treat people over two years, you simply have much, much more data. Certainly so. Um, what we don't have in there at all yet are interactions, because even simple things like vitamin C and calcium, right? If I drink vitamin C with milk, it's not blocked 100%, but it is relatively

Much. Yes, that is totally unintuitive, because you have a lot of C in it and you drink a glass of milk, both taken on their own could be presented as very, very health-promoting. If you take them together, then you at least have the vitamin C component, which is no longer absorbed. So, to figure that out is absolutely impossible if you don't stumble upon it by chance. So, how is it with all the peptides uh and with the biohacking approach? Because one wants more of it. Okay, less fat, yes, great. I'll do that. More energy, great, I'll do that. Better sleep, I want that too. And besides, I want, I don't know, do you still have something like flying or superhuman? So, all of that sounds awesome. So, and then I would get a stack, that would be, I don't know, 50 tablets a day, or inject here, inject there, then wait half an hour, then the next injection, and at the end of the day, something blocks itself or I inject my tumor to grow bigger. So, how can I protect myself against that? First of all, what we first have to say is clear, I also deal a lot with the area of entrepreneurs, let's say, who want to optimize themselves. That is of course interesting. A large part of what I do or what we also do is of course also a bit of what I just explained, immune deficiencies here and there. So, we do relatively a lot of the health thing, but over-optimization is of course a topic that also interests people. Um, a very simple answer, these are all pathways that already exist in the body. That means we know quite precisely what they do. Accordingly, we also know what an overexpression of these pathways does, and we also know in part what the overexpression of two of these pathways that intersect does, because we know that from various disease models. Accordingly, one must pay close attention to such things. That means, that's why I say, if you don't inform yourself about it and don't know what they do, it's difficult. It's relatively difficult if you understand all of this and the research in this direction, it often goes there, because you all have to understand a bit, research is very critical. That means, the interpretation of research is always such that you say, this could do this and that. As soon as any active ingredient does something, it is immediately tested for what could harm it. So that is always taken into account. In every study, there is also Adverse Events and this and that and that and that and that. That is very, very important. And if you take that in a bit, then you are still not 100% sure, but then you at least understand what can happen there, what can happen there, and which signaling pathways, for example, angiogenesis, is caused by BPC 157 healing. However, in chemotherapy, angiogenesis inhibitors are used. Accordingly, it is logical to say, upregulating angiogenesis, difficult or because of cancer. Exactly. That means, it is a good assumption at first, right? That means, you get ideas from that, right? So, that's how you have to see it. For example, another molecule, SLUPP332, is cardio from a pill. It is currently only in animal studies, very new. Mice had 70% more performance, 25% more fat burning, and lost weight without changing their diet or exercising more, just by taking it. Accordingly, one asks oneself, where does that come from? And they looked, it's various receptors that actually only become active during endurance training, and they want to target them specifically. So, that is the targeted pharmacological attempt to make endurance training accessible. And then you look, can that have effects on the heart? Everyone asks themselves that. Logically. And then you look at the receptors and know, these estrogen-related receptors, that's what they're called, they are also active in the heart. However, they tend to increase the oxidative capacity of mitochondria, i.e., of muscle cells, increase their stress resilience or resistance in the heart. Now, a counter-experiment has been done. If one of these receptors in the heart is inhibited, it leads to heart failure in mice. Accordingly, it is more likely that it seems to be beneficial for the heart. So, that's how they try to make deductions, also scientifically. And that means, you are right. There are no studies that investigate the two things simultaneously over a longer period, but in every study there are always efforts to see where it actually leads. If you look at it in parallel, then you can see relatively well, this doesn't happen here, but does it happen somewhere here, perhaps. And that's all we have. So, yes, there are no studies that say what happens if you take 17 peptides together for 5 years, but if you deal with each one, you can guess what you might want to combine or not. And of course, that is an extreme case, which you also mentioned, that you take so much and so on, right? Means, I don't think you can't guess it at all, because many people always say that and I actually have a different opinion, because if you see all the studies and the literature, it actually provides quite a lot about it and people always act as if something magical suddenly appears. That's not possible at all. So, we all know receptor pathways and we know what can happen, and it is very, very rare that something happens that we cannot foresee. And I am also 100% sure about this muscle drug, that I know and that it was already known beforehand what would likely happen, that one simply hoped that it wouldn't be the case, right? Yes, that is interesting. That means, if I approve such a drug or such a peptide, I say, okay, I know, if I now, I'm thinking if there's an example in real life, a car. Yes, if I now, let's say, a fuel pump that used to exist, if I make it pump more, then more fuel enters the combustion chamber. So, it explodes more, more power is generated, the car drives faster. That is relatively clear. So, now I say, look, I'm going to make a drug that increases the performance of the fuel pump. So, and now you have to be careful, because the side effect could be that so much fuel enters that so much power is generated that it breaks somewhere else, or that there is so much fuel in the combustion chamber that it no longer explodes, that there is not enough air in it. So, I already know that. So, that could happen. What will not happen is that the tire pressure decreases, because it has nothing to do with it. So. And then we say, okay, if we adjust the drug like this, that it increases the fuel pump's performance, its throughput by 33%, then we have a drug that makes the car drive faster. But if we mess it up a bit, then either the car stalls or the transmission breaks. So, those are the two possibilities. So, you think about it, say, but we can manage it. Uh, from which perspective do you mean that now? So, from the perspective of the biohacking community/pharma community or the pharmaceutical industry, which says, we know the signaling pathway. The fuel comes into the combustion chamber, a gas, a fuel-air mixture is created there. It explodes. Great. If we make more fuel, bigger explosion, more power. So, then, but everything that is connected to it. But it's not the tire pressure. That is independent of it, but it could eventually, if I drive very fast, the tire gets hot and because of that, the tire pressure somehow increases. But that's thought out about 28 corners. Exactly. I think from the perspective of the pharmaceutical industry, especially with this drug for muscles, I think it was thought that maybe the heart might grow a bit too, but if we build this and that in, it shouldn't actually happen. Then you do the first preclinical studies, see, hey, it doesn't happen, great, more money. Phase 1, nothing more happens, Phase 2, oh damn, maybe it did happen at higher doses, for a longer time. So, that's how it probably works from a pharma perspective. And from a biohacker perspective. Yes, relatively similar. So, we have to distinguish, of course, if you eventually start taking things and then are only there to fix the side effects of those things, then that is destructive. That should never be the way, and a biohacker doesn't do that either. So, that means, a biohacker specifically chooses the things that might help him at that moment and uses them in such a way that they solve a problem for him or perhaps give him a bit more of something. I would also include entrepreneurs in that, because I don't support trying to constantly chase after and try to bail water out of the ship as best as possible, because I don't do that. And that's not how it actually is. So, it sounds like people optimize so much, but in reality, these are all small changes that you make with these peptides, for example, or with sleep, for example, you also do that with peptides or with older antidepressants, right? The Trazodone example, for instance, Christian Wolf also received quite a bit of backlash in a post. Everyone got upset, I said, logically, that's how it's done, doctors also do it, right? But the outraged society is immediately there. So, it often sounds bad, but especially if someone is into the topic and understands what's happening, they will usually look at you and say, it makes sense, right? So, here everyone is outraged about all the active ingredients I've just talked about. In the USA, they sit in podcasts and talk about it openly, especially medical professionals, not all of them. There are also people there who are against it, who don't see it as cool, but it's much more there, right? You can prescribe that as a private doctor there. As soon as a pharmacy or a compounding pharmacy does it, you can prescribe it. Accordingly, things like Thymosin Alpha 1 and what do I know, Ipermorelin and whatever. So, all those things are also used there. Trazodone is also used in Germany. You just have to find a doctor who understands what it does. That would be this sleep medication, which used to be an antidepressant. That means, if I now leave our conversation enthusiastically and say, "Look, Mike, write down for me what I need to get?" Yes, so, you give me a list, then I go to my doctor with the list. Listen, I did a podcast last week. For one thing, I have to take Testo, then this and that and that. Then he will roll his eyes and say, half of that I've never heard of. Who did you get that from? Then I say, from this Mike. So, Mike is completely out there and he said, trust me, Bro. Then the doctor will say, no, no, he's not a doctor, but he's looked into it a lot. So, then my doctor will probably say, you're crazy, kid, and please never come back. Because if you talk like that, I can't help you anymore. Um, why is it that you know so much about it and say with so much self-confidence, look, take this, take that, disclaimer, I'm not a doctor, you have to know yourself, so to speak, and you can get it at the pharmacy and on the other hand, maybe somehow under the bridge, so to speak, yes? Uh, and then XY will approach you, I don't know. Um, and [laughter] that is actually, if you zoom out a bit, absolutely insane. Yes, it's interesting. I think I have two answers. The first is, I would definitely not argue with the doctor, because that never leads anywhere. So, many doctors know me by now, it sometimes goes more positively than you think. In fact, I am also contacted by many doctors. I also have relatively good contact with many doctors. So, we are on a cool level now, but there are also others. So, maybe don't argue with me, maybe you're lucky, maybe you're really unlucky, because there's no in-between. Most people like me, and the others hate me. Argue with the people who really have authority and do that. For example, Dr. Peter Attia, he is world-renowned. Send videos of him. Dr. Craig Cowen, for example, too. These are all experts who openly talk about it in podcasts in the USA, that they successfully treat patients with it. That means, it's not just some crazy person. That means, in the end, I would argue with them first, before you take me. And secondly, why? Because no one else does it. Nobody. So, what I do, nobody does. Accordingly, I am not a doctor. No. But what the good Timo Osterhaus, with whom I sometimes do podcasts, many will know him, once said to me in a podcast, you are not a doctor. That might also be a good thing. So, a good doctor was lost in you, but the colleagues with whom I do these projects also say that. You have to do this. We can't. We're not allowed to. You have to talk about it. We're getting ourselves into a devil's kitchen. I am an interface of many, many different fields of study that one would actually have to take and complete in order to have this knowledge. Nobody can do that, and a doctor is very far from it. Accordingly, I have an interface. You have, for example, an endocrinologist, a biochemist, a pharmacologist, a nutritionist, a sports scientist, a food technologist, perhaps in the sense of supplements or something. Many different things. And somewhere here is the interface, in which I am in the middle. I haven't fully studied anything, but I have enough understanding of everything to form the overall picture and help someone in practice. I've been doing this for 10 years now. Thousands of people, numerous blood tests, 30 to 40 a week alone, working with doctors for three or four years, together on an equal footing, and it's a very good collaboration, and it's true, there's no data on humans officially. And what I have, that's data on humans. It's not randomized controlled trials. I'm not at their homes, but that's all we have. And that means, why do I do it? I developed into it. So, it's not like I asked for it. I developed into it in my interest. It developed, developed, developed, and now I have to say, I wouldn't know what else I would do if I didn't do it, because it's my passion. It's incredibly fun for me. I sometimes spend 12 hours a day with studies. I've been building a masterclass on the topic for over a year with over 200 videos so far on 15 different topics. It's not just about over-optimization, but it's really about solving complex problems that people can solve without being pumped full of medication by a doctor. Or the typical problems where you are sent home, where you are told, we can't do anything, that doesn't exist, you don't do that, or here, whatever, that is a passion. So, I sometimes sit for 12 hours a day, when I'm not doing other things, I sit there and just read studies and put together this masterclass, for example, because I have an incredible passion for it. Accordingly, yes, I do it because no one else does it, because there is no one who does it. That's how I came into being at all. If there is someone with a profession who does it, I might be unemployed at some point. Until then, I will continue to do it. Yes, although Germany probably also has room for two people who do this, right? Or maybe even three. There are probably not, I don't know, 500,000 doctors, not quite that many, probably more like 200,000 I would estimate. Um, and if one or two or three people say, do a bit of biohacking, then that doesn't directly affect your business, right? No, no, no, no. So, absolutely welcome. I would welcome colleagues too. So, I feel like there are always approaches in this direction, but not so many. But honestly, what I see is, maybe it's just because of the bubble I'm in now. I now deal with a lot of doctors, especially younger ones, and they are extremely open-minded, extremely interested. I also have some doctors in coaching, and one who, with me, well, one, I don't know what to call her, an employee or a girl, her name is Miri, I coached her before, she went on stage, we've been a team for ages, so to speak. She is a medical student, has been in my coaching for ages, and people like her with their open-mindedness, with their interest, they are the future of medical professionals in Germany. That's why I say, eventually I'll be unemployed in that regard. But that's okay too, because what I'm seeing now in medical students, what the next generation is, there's a lot of really good stuff there, and they're growing up very differently. They are intrinsically motivated. For example, Timo also Timo Rusterhaus with his Methletics Academy, which he runs, where he wants to help doctors to really continue their education, because no one does that in Germany. This continuing education doesn't exist. He says so himself, he criticizes it, and that's why he offers this academy, and it's great, I got it myself, simply because I want something like that. I also did a naturopathic training, simply because I'm interested. I didn't take the exam, so feel free to hate me for it, but I didn't want to be a naturopath either. Accordingly, I seek out all continuing education that I can find in this area, plus the studies, plus the practical experience with people. And every person who comes to me decides for themselves whether they believe that I can advise them or at least give them tips. And we have doctors in the background who conduct health checks at any time and are there to support it. Accordingly, I usually don't mention them publicly, because they might otherwise, well, face problems, but maybe we can do that soon. Has anyone ever tried to shut you down? Me? No, that, because from doctors I get that relatively often, that you can complain to the medical association very quickly, and then you just have to write a letter. Say, look, he's stupid because he said, I don't know, apples are healthy, so, and then someone has to sit down and say, wait, can a doctor say that apples are healthy, because the study situation with apples, isn't that somehow taken out of context, haven't you seen? So, and that's the problem. That's the problem. And they are also quite afraid of that, I get that impression. Yes, that something happens, but it's good that it hasn't happened to you yet. And what I see is, of course, an absurd, so to speak, two-tier medicine, because we already see that with Osemp, that at least in my perception, people with money are no longer fat. So, you also see that in politics, that all of a sudden people lose weight as if by a miracle. Um, and it's relatively clear where that comes from. And now, when I listen to you, it's clear that if someone says, look, do you just want to lose fat, or do you also want to gain muscle? And besides, you want this and that and that. Then it's just a question of, yes, okay, what does it cost? Because nothing is free. And if I can afford to sleep two hours less and have a bigger biceps, yes, where do I sign and where is the checkout, so to speak? What does that cost currently, if I were to say, look, I want the basic package, not in the sense of, I don't know, ultra tracking, but everything that makes my life better. A bit of Testo, a bit of that GLP1 receptor thing. That's not so expensive. That's okay. Um, that with the, what did you call it? Two-class medicine society. How did you call it? Two-class medicine. So, in the sense that people can afford it. So, the insurance companies all say, "Look, are you sick? Can you still walk? Okay, if you can still walk, then you're not sick in the legs." Um, and that's like the car that drives 120. Exactly. I wanted to pick up on that, because I think it's great, because it's decided between, and that's the sad thing, that's the first question. If you want that with medical supervision, then private doctors do that, logically. So, an insurance doctor doesn't do that. Is it perhaps only due to financial freedom, means, whatever, but I also only work with private doctors, because I've found that insurance doctors don't do it, don't want to, whatever. Therefore, that's the first thing. But to get to the question, testosterone costs almost nothing, right? So, it's really incredibly cheap as a medication too. For a THT dose, it costs about 70 € every 5 months. Then the private doctor costs, depending on his hourly rate, it costs, and you only need an hour for a conversation and checkups and everything else. It's actually done via telemedicine for us, meaning you don't have to go anywhere. That's the telemedicine support via the internet, and you really have a video call, not just a questionnaire. That probably costs around 200 € per hour at the moment, I think that's about right, and GLP1s, they are more expensive, right? So, we have to take Monjaro and Osempic, the approved ones, they cost about 400 € per month. I would almost claim that's still just about affordable. Now comes the thing, though, 400 € every month until the end of your life. That's a lot. That's why now, and that's usually where the decision is made on its own. I often say, you can go to our doctors, then you'll get the product prescribed from the pharmacy if it all fits your profile. But it costs, if you buy it on some website, it costs a fifth of that or so, and it works just as well, right? Therefore, people's decisions are usually relative, which is why this market is booming so much, which is why it's relatively independent. Even if a Retard Tide, so this new GLP3, Retaile G, comes onto the market, I assume it will be more expensive than Osempic, and I assume everyone will want it. I believe that when it comes onto the market, it will not have a negative impact on the black market. The black market is booming with it right now, and as soon as it comes onto the market, I believe the black market will profit even more because the hype will increase and people will think, who the hell can afford this? Because you said something right, and I often get that feedback in coaching. Not everyone can just spend 1000 € a month on it, and then people ask themselves, okay, either it remains completely unattainable for me, or I get it cheaper for a fraction and do it that way, but I have the same effects, and that's a double-edged sword, because of course not every source is clean, we all know that, right? But in some cases, like with Clomiphene, for example, there's sometimes nothing else left, right? So, it's a difficult field. This whole biohacking is difficult. The SLUPP332, which I mentioned earlier, the cardio from a pill, which I've also been trying out for a very long time. You can't get that, of course, because it's only just emerged, 2023. You can't get it anywhere, not even remotely approved. Forget it. But as you said yourself, the first patent applications and so on or applications are visible, the first studies are visible, and one always forgets that the active ingredient manufacturers, they are not farmers, they are not idiots with a bathtub, but the active ingredients of all peptides, they come from China. Even the HGH from German pharmacies comes from China. All active ingredients actually come from China, and the people who work there are scientists, scientists, only some supply laboratories or pharmaceutical companies, and others do a different business. But in the end, you have people, dropouts, for example, from Ila Lilli, who found such underground laboratories. But where does the illegal start, so to speak? So, if I now, let's assume, go to the website of the USPTO, then I download the patents, then I see the ingredient list for these peptide stories, but wait, the peptide itself is not the ingredient, but a peptide has ingredients. Yes, a peptide has an amino acid structure. Those are the ingredients, if you will. Um, and it says, I'm downloading the recipe more or less from the patent, and I order the individual components, and at the moment I mix them together, the product is created. That means, if I now legally buy the ten building blocks, then I can, in my garage, hypothetically, of course not, but purely from a legal understanding, then everything is clean. The components are 100% clean, because I can only get them. It's not like, what's it called, coke or something. The substance itself is not illegal, but the substance is legal, and I'm now, so to speak, baking a cake from the ingredients, and I've baked the cake. Exactly according to the recipe, and in principle, the components of the cake are all legal. So, only the baking of the cake, that's my illegality in that case. And then, if I make a cake, if I make a chocolate bar, I could go to the supermarket, then I buy some caramel, some peanuts, chocolate, and then I sell chocolate bars. They are exactly like a Mars or a Snickers, but if I call them Snickers or sell them as such, and if it's an original Snickers, then I'll have problems. But if I sell my homemade Snickers, which is like a Snickers, under the brand name, then I could, I shouldn't, but the risk that I have with the Snickers that I make myself, there's nothing difficult in it. It doesn't require a secret ingredient that I have to produce somehow, but I have to execute the recipe correctly. That means, the risk, without wanting to downplay it, just to assess it, these underground laboratories are usually normal production facilities. Okay. So, especially in China. Especially in China. So, just imagine, you often hear former employees of large pharmaceutical companies starting such things. They want to earn more money, are dissatisfied, feel creatively unfulfilled, so there are all sorts of reasons. Um, and that changes the situation a bit, of course. And to your question, the countries have different rules, right? So, different laws regarding all of this. The amino acids, we agree, right? They are all legal, absolutely. And as soon as you bring it into a composition, it could be, when it's finished, a substance that is illegal in many countries, and that's where most peptides are distributed in Europe, for example. It's so that these substances fall into a gray area. As long as you put them online and say they are for animal testing, you can sell them. In Germany, they are hardly regulated at all, right? So, in the end, it's a gray area, and maybe it will blow up at some point, we don't know. Currently, it's more illegal than legal, logically. Um, but most officials can't really do anything with it, and much of it is also not regulated. And in some countries, where you are allowed to put it online for animal testing, it is then put online, and suddenly you can order it. A nice example is also Elkanitin. Do you know it? Elkanitin is legal. Elkanitin also exists in injectable form, and in injectable form in Germany, it suddenly becomes a medication, and theoretically it falls under the Narcotics Act. It is more potent as a medication than the oral form, we all know, it does almost nothing. Um, therefore, it differs, what you just said, the amino acid form is the same, the way you offer it, what you offer it for, or in what form it is then offered. Because in Germany, basically everything that you inject yourself is actually, because you are injecting yourself and could hurt yourself, it is a problem. So, you won't get approval for people to inject themselves with something. So, we already have that hurdle, right? One could also say, it's for animal testing, but well, I don't know. Yes, it's a crazy world that's opening up. It's difficult because apparently with a little money and a little knowledge, you can definitely buy yourself a stronger body. And it used to be that this whole dating selection behavior was, if you now, as a bodybuilder, walk in somewhere, or at least as a trained person, then your body is a testament to your lifestyle. So, and I worked for that for 10 years. So, look here. Here I am. So, and what's coming now, and what you're already doing, and what will probably get bigger over time, and isn't going away tomorrow, is that in 20 years, when we have many more substances and it's much more common, that everyone who has money will look trained and great and well-rested, and everyone who doesn't have it, will tend not to be anymore, and then you can more, but they will also look the same. So, because if you can be trained, anyone can be trained. Everyone wants to be trained. Nobody wants to be fat, everyone wants more muscles. It's relatively clear. Except for the body positivity bubble, which of course can then be fat-affirming, so that they get even fatter, because they find that super beautiful. Exactly. They will continue their secret Osempic transformation, as is known now. I am of the opinion, because that's how I do it, and that's how everyone I work with does it, that personal effort will always remain a part of it, because as you said yourself, it shapes your character and you radiate that, and I think that still makes a difference. Maybe in 20 years it will be the case that it's no longer necessary.

I find it a shame because I am for self-optimization, but for me, self-optimization means that I use Trazodone for sleep because I improve my sleep quality and my deep and REM sleep. But of course, I still sleep and I want to. And of course, I do training because I love strength training, but I don't mind getting a little less body fat and more muscle gain from effective training and thereby perhaps saving a bit of time. But I love training, it won't stop. I love healthy eating and yet I am happy when I am a little less hungry throughout the day and have no cravings. For that, I eat more in the evening and even if I stuff myself, I don't gain weight. At the same time, my liver gets healthier. Still, I don't want to stop eating healthy. That doesn't mean I eat pizza every evening. I don't want that at all. And I have the feeling that many people feel this way. And these are the people who benefit the most from it, because I am still of the opinion at the current point in time. You have to do an incredible amount yourself to achieve such a result or many other results. And it sounds harsh, but I also somehow wish that it stays that way, because it is something special and it is also a discipline that extends to so many areas of your life and sharpens your personality so much, and if we lose that, then it will be a strange world. In plain English, these are all wimps, right? Because they are people who don't want to achieve anything anymore, who don't want to do anything for anything anymore. And I believe it will never come to that. I hope so at least. And I believe there will always be an advantage for those who do it. And these are the people I work with. So, I don't know if people haven't gotten the wrong idea. It's not like I invite people and say, you're not moving your ass anymore. I'll take care of the rest entirely. That's even absolutely, you're out with me, right? That means I always demand great effort. Bring a lot, and the more I feel you take responsibility for the matter, the more we try things out, because then I feel that the extra thing might bring something. The difference is illnesses, quite clearly, so obesity or what do I know, diabetes and so on, where it's obvious that if someone takes something that lowers their long-term blood sugar by 2% and they have fatty liver and diabetes. Of course, you do that, you don't say, but first, show me what you can do. Help him. He has a problem, right? Cardiovascular risk, mortality, everything increases, that's something else. But especially these optimizers, maybe I'm an idealist, they have to work hard themselves somewhere. Even if I like to publish these experiments that I sometimes do on LinkedIn and so on, because there's an extreme advantage if someone comes to me and says, €5,000 a month, come on, let's try it, let's do it, but that's not the methodology I actually use. I don't want to attract people who want that either. I want those who have the will to do something themselves. That's important to me. And I select, so you have to apply to me, so to speak. What do you select based on? Exactly that. So in the initial consultations, I sometimes have the feeling that people believe they can buy me. That means, um, like, I'll book you now and then you'll do what I want. No. Um, secondly, does the person have responsibility? So, do they have any feeling that they know that they brought themselves there and that they know that they have to change something about it themselves? And that's very, very important to me, and of course, humans really don't spare themselves anything. So, if I have the feeling that I don't get along with the person from the start, which is rare, but sometimes there are people who act like that, then you think, wow, go to someone else, because there are many people who want to make money and my coaching has been really full for a long time, that's why I'm currently working on the masterclass. That's why I have other coaches in the team. I don't need to increase my coaching further. I also don't want to advertise my coaching here, maybe for my masterclass, because it will be interesting for everyone. But that's the beauty of what I do now. I look for people who really need it, where I have the feeling, okay, that's an interesting story, let's talk to the doctors about it, do we want to tackle that, or where I say, okay, likeable, I'm up for it, you have the right mindset, let's do it. And that's how it is, but they apply to you, not to the doctors. They apply to me. Yes. So. And you just said, okay, every now and then you have to have an hour with the doctors, then the doctors take €200 or something? So. How does it work from that moment on? You, I'm applying to you now and saying: "Listen, I'm Ben, I'm a really cool guy. And make me cool, make me cooler, as it used to be called. So, then, um, you talk to me briefly, say: "Listen, basically yes, but you're a complete idiot, but I'll turn a blind eye for you." So. Um, and then what happens next? So actually, it's like, depending on what you do, you have different things you can apply for, and it's very topic-specific. That means, if you have a testosterone deficiency and you're not being helped, you apply specifically for the THT coaching. That exists. You have to submit a blood count and then you have an initial consultation with one of the employees who is in direct contact with the doctors. That's Lukas, he's been doing it for me for years and is super fit at it and is directly on the short line with all the doctors. And after the consultation, you immediately get an assessment, whether you are a candidate or not. If you are, the coaching begins. You get a health and optimization concept and so on from me in conjunction with a consultation with the doctor, who checks you again, examines your blood for further values again, and then we jointly start the THT, and the doctor naturally costs extra. So the doctor is an external point of contact who works with me, but that comes on top. So that means you know beforehand, if you apply for coaching with a doctor, for example. The Weightloss Coaching, that also exists. The goal is really to change your life within a year with an Osemp Monjar or Reta, and during that time, diet and exercise and everything else will be adjusted, and at the same time, you get the opportunity to use the medication. During this time, you have to manage to change your life. And with all other coaching systems, it's like, after my assessment, if I say, I can entrust this to the doctor, yes, not that you sit there and say, hey colleague, get me Testo, right? If I, if I, there are people I would never send to one of our doctors. Um, but that's, they also appreciate it very much about me, that I know who I'm sending to them, and then it's like, I talk to you and say: "Listen, there's an option with our doctor for this. Talk to him, I'll talk to him beforehand, if that's okay with you." And then there's an option that we can intervene with thyroid hormones with this or that, that you've been prescribed normally, and then you decide whether you want to pay the money for the doctor or whether you say, I get thyroid hormones from my buddy, I don't want to go to the doctor, right? So there is that too, right? Therefore, but some people feel better and accordingly, I also do blood tests, but we also do it in conjunction with the doctors because it's just a nice way to work, right? Yes, but what you or what I understood roughly in the first two hours is that it's essentially, you start with Testo and then you take this and this and this, and now you have a product structure where I have to apply for Peptide 23 246, so to speak. But I don't want that, because I just want the package, so to speak. So, what do I give, I understand that then you start in a coaching, then they know others transfer, then you do what everyone does. What does a breakthrough customer get? What does he leave with you and you guys per month for the whole topic of biohacking, not just with you, but also with possibly the underground pharmacy or whatever, what does he invest per month? So exactly, you said it right, right? It's not limited, right? If you decide on normal coaching, you can do anything in any direction, right? That means, Peptide XY coaching doesn't exist, but everything is always completely overarching. It only serves to know beforehand how to assess the person and where we might need to classify them, so that we also know, this is a bit of a serious case, he just wants to optimize himself a bit, there's something going on, we need to look. Um, wow, that's so hard. I can tell you that I'll start, I'll do it with an upper limit, maybe, because I think that's quite good. People who spend little but have quite a lot of effectiveness, they spend around €400 to €600 for medication and C, and that can actually be less. Then you have a good basis, and if you really want to go overboard, let's say, you want to try optimizing everything from this SLUPP 332, for example, from this cardio pill and two or three different others, and from the Reta and here and there, then you're looking at definitely €1 to €2,000 extra costs. I also had someone who wanted to do it for €3,000 plus. We really tried a high dose of everything and saw how much fat he burns, and it worked very well. Um, I've naturally done it myself before, so on the way to the last Fibo, I tried it out. I actually took so much of this slupp 332, so I tried to reach the mouse dose from the studies, because they really didn't move and had sensational results. It's not possible. So with the human dosage form we have, we can't get there. But that also cost a lot of money because at the time I didn't have sponsorship from the company that distributes SLU. Now I have that, and they probably wouldn't have gone along with that nonsense either, but I think I spent €3,000 a month for a single peptide, yes, with F amino 1MQ. So that's similar, it does something else. One is that your body switches more to fat as a fuel source and simulates endurance training, so to speak. The other is for glucose metabolism, for ATP, so for more mitochondrial activity and also for fat burning, if you will. And the two combined work very, very well together. And I took these two at very high doses. That was about €3,000 to €4,000 a month that I spent. Yes, it's crazy, right? I mean, clearly two classes of medicine, so, uh, I mean, that's experimental, but if you say the baseline is €400 to €600 for the basic package. Um, at the doctor's, where I haven't been yet, there's a sign for prescriptions or no, for sick notes we have to charge a fee of €200.50, and below that came the disclaimer that it's not possible otherwise and this and that, where you see how much trouble they've already had because they charged €2.50, and you say, hey, for €400 to €600 you can already get a basis, right? So lifelong per month, right? Not necessarily. So I see it that most things are done until you reach a status quo. I also haven't, for example, reached a body fat percentage that I'm happy with, then I don't take the things anymore or less. That means it always depends. I would consider the basis long-term to be less, but that's individual because everyone says, when I'm done with this, I want to try something else. So I would say approximately the Frankfurt applause here no front, accordingly, let's say constant, but not for one thing, right? You can fix one thing for it, and then you can reduce it. But what I also have to say clearly, and it's sad because I come from that past myself, I used to have no money for anything. It hurts, but accordingly, if you don't spend much, then you're at the basics. Do the basics right and everything will be okay. If you want to go beyond that, then it usually costs money. That's how it is everywhere. Accordingly. It is, I don't make the rules. Yes, it's a powerful lever. If I now consider, Mcfit costs, I think, €20 a month or €25, depending on how you're feeling. So a protein for a month costs I don't know, €30, €40, so a protein powder if you do that. So a vitamin Omega 3 is relatively expensive. So Vitamin D, the normal supplements, they cost almost nothing. So, but Omega 3 is quite expensive if you take more of it. Definitely. Um, but then of course it's a huge step to a mid-three-digit amount, but people do that because they, and they also do that, it must also be said fairly, if it didn't bring anything, then they wouldn't pay €1000 because it hurts every month and then they stop. Is it possible to stop it? So to say, I'll try something possible, then I'll blast myself and then I'll say, listen, I have less money now or don't want to anymore. So stopping testosterone, I believe. Yes, so we've clarified or can address it again. Testosterone is difficult to stop overall, but it's actually relatively easy if you do it right. So you get in 99% of cases, maybe you want to. I haven't experienced it not being the case. I do a lot of withdrawal therapies, so we often do that, and you actually always get your testosterone back, but it's just as bad as before. That means, that's your decision. In the end, it's easy. So stopping testosterone, there are people who say, you'll remain infertile, you'll remain this, you'll remain that. That's such nonsense. I've never experienced that, and I wouldn't know how to explain it. So, if so, then it must come from somewhere else, because we actually have people who come from all sorts of backgrounds and therefore either have no fertility or no testosterone. We always manage to fix it. We've never experienced it not working. We've been doing it for years. So that means, you can stop testosterone. It's just a bit of a stressful process until yours kicks back in, but we also manage that relatively quickly now and bridge it well, right? That means, it works for everything else, nothing happens at all if you stop it. It just doesn't work anymore. That means you have the effect for as long as you take it. And if you have managed to establish a lifestyle that ensures this by then, a good example here again with Osemp and Co. If you have managed to establish a lifestyle that ensures this, then you can keep your results. And that's something beautiful, isn't it? Especially with Osemp, you have someone who is overweight, does it. During that time, he changed his life and then he stops taking it. We have a bit of a pharmacologically explainable initial increase in ghrelin again, the hunger hormone. It's normal, but it normalizes again, right? And then you're back to normal and can just do it. But aren't the Osemp people permanently on Osemp? Um, many are. Especially, I would say, very many of them don't understand that they should do that, right? Because otherwise you'll eventually realize, I'm at a certain status quo, I'll stop it again. And then we have those who do it for lifestyle reasons, because they want to afford the luxury of not having cravings anymore. I'll be honest, I'm one of them. I've been dieting for years, probably almost a decade, I've tried every diet, and I'm good at it. I'm extremely good at it. So, for my mental training, I've overcome hunger for a while. I wanted to feel where this hunger is, where everyone gives in, where everyone says, I feel so bad, I'm going to be sick, I'm going to faint. I wanted to know what happens next. I just waited. So, that's something I generally like to do very, very much, and I've trained myself or unlearned it, and at some point I told myself, I don't need this anymore, and accordingly, that's the philosophy I follow, this fifty-fifty of discipline and help. I take away a bit of craving and get full faster, but I don't kill my hunger. And these are people where I say, you could do that long-term if you have the money and if you want to. That's luxury, you don't need it. Yes, of course, you have better blood sugar levels. Of course, you are metabolically a bit safer, if you will, but you could stop it at any time, and then it's up to you. In the end, if you are disciplined, you can stay at the same weight normally. Logically. How much do you take per day of various substances? The question is, so on an average day. I understand that it fluctuates for you, that you try this and that, but roughly. I have a rough setting, I think, that I would also maintain. That's this GLP3, as we call it now. This Triple G is called that because it's three times the agonist. 3G for sure. That's this hunger suppressant, which I always have in a very low dose. But you only have to do that once a week, twice a week at most, right? Some people feel better if they split it into twice a week. Of course, testosterone in THT form. Then would How much do you take? How much Test do you take? I fluctuate, so I have 250 mg available per week, but I usually do around 150 on average. Sometimes, if I feel like I want to build up a bit more, I go up to 200. But I'm someone who, first, I aromatize very strongly. That means, I convert very quickly into estrogen. And secondly, I'm also someone who always retains a bit of water, and that doesn't suit me in my face. I always get chubby cheeks. I'm not a fan of high testosterone at all, and that's why I usually keep it that way. The highest it gets for me is 250 mg a week, but rather in the 150 to 200 range. I feel comfortable there, I have no side effects, and I function great in every respect. Uh, Tadalafil, I actually take non-stop. So F is the active ingredient from Tadalafil. Exactly. Cialis Tadalafil is relatively good. Firstly, long-term when taken as a mild fat burner. Secondly, blood pressure control. Thirdly, prostate support, which is not so important for me yet, but we use it a lot in coaching for that. Then we have androgen receptor potential, which goes up. Accordingly, it means your androgen receptors increase, your testosterone docks better. Less testosterone becomes more effective without more side effects. The same is done by Elc Carnitine as an injection, which is why I also do it regularly for a while. And accordingly, Elc Carnitine is in there occasionally as an injection, not always. The SLUPP332 is more frequent. What do you decide based on? Today a bit of Elc Carnitine and today not. I do it in phases, so that means, because I don't feel like injecting myself with LKTIN every day, and I think many can relate to that, and I'm human too. That means, I say, I'll take this for, say, two months, then I'll do it. In fact, it's really interesting that through increased fat oxidation, you have more performance. You also feel it in training sometimes. You have better fat burning if you are in a deficit, otherwise it doesn't make much difference. Better energy level, and well, through this increased androgen receptor density, you actually have the possibility to ensure that your testosterone is more effective, and interesting indications, or rather, it can be relatively well proven that it also helps with sperm quality. So we also use it in fertility therapies during that time, among other things. There are many different medications involved, but also those that are actually nothing more than healthy, because Elc Carnitine, just because you inject it, doesn't suddenly become unhealthy. We agree, it either does nothing or it does something healthy as a capsule, depending on which capsule form you take, right? Most do nothing, a few do a little, and if you inject it, it's even stronger and the effects are better. And therefore, Tadalafil is also quite cool because you have a bit of a better pump in training, and blood pressure control is also quite good at 5 mg a day, which I take, I would say the influence on sexual activity is minimal. Yes, for people who hope for that, they have to take a bit more, but you do feel a difference, right? It's a bit better. Um, otherwise, the SLUPP332, which I've mentioned several times now, is this capsule that simulates cardio, but I love cardio and movement. I move a lot every day, but with SLUPP332 it's more effective. I use more fat as fuel, and the oxidative capacity of my mitochondria is improved. Apart from that, these estrogen-related receptors, these ERRs, are active in all mitochondria-rich organs, and we have studies, not directly on SLUPP, but indirectly, that in old age this ERR activity in the organs decreases, and as a result, mitochondrial dysfunctions occur in these organs, which lead to age-related diseases that we know. In an experiment on mice, the estrogen-related receptors, by activating SLUPP332, led to the resolution of kidney failure. Crazy. Now, one thing must be said, these are mice, yes, but beforehand, the estrogen-related receptors function exactly the same in us humans, and they exist exactly the same and fulfill exactly the same tasks, and the distribution in the tissues is also the same. So, it's completely analogous. We don't know more, but I believe in it. Therefore, for me, noticeably more energy, more fat burning, more performance. It's easier for me to do cardio or martial arts. I also do a lot of martial arts as a hobby because I love it. And overall, for me, lifestyle-wise, a gain on every level and a long-term investment in my health that others don't make. I have an advantage, if you will. Then that's pretty much it. I always switch things around a bit. I'm also a fan of briefly adjusting thyroid hormones to the upper range of the reference and the TSH below it, which German health considers healthy, because the current data suggests something completely different, and I want my TSH and my thyroid hormone balance to be there. And often, due to various life factors, little sleep, stress, whatever, they shift, and especially if you are in a deficit for a longer time, it can be that your thyroid sometimes does a bit less. If you keep it at a normal level, you not only have better fat burning, but you also have more cognitive performance, because T3 is damn good for your brain. You have more performance in training, because T3, for example, promotes muscle contraction. So of type 2 muscle fibers, which contract better, you have more performance, and also T3 is anabolic. So T3 also ensures that, for example, muscles or muscle metabolism run better. Only an excess of T3 is muscle-wasting, but we don't want to go there. Therefore, here too, I gladly optimize. I could continue a bit, right? It's not like that. Thymosin Alpha 1, I use it every time I feel like I'm getting sick, and then it doesn't happen. So it's still there, and if so, only very briefly. Actually, for sleep, I use 25 mg of Trazodone. Sleep values have improved extremely since then, and yes, as I said, I could continue for a while. Yes, crazy. What we haven't talked about at all, but we have to bring it in very briefly. Um, there are people who say, we don't need to take Vitamin D, because that's nonsense. I eat very healthy, and besides, supplements are stupid, and you can't take ten capsules a day. It's clear that it's unhealthy. Uh, I'm beyond that stage, and I think you are too, and I don't think, I'm very sure, uh, there's a supplement stack where you say, that's absolutely a no-brainer, and there's also no discussion, like with all the peptides, where, yes, that's new, we don't know long-term yet, but that Vitamin C is good, and Vitamin D is relatively well-known, Omega 3, Omega 3 too. What would you recommend to everyone blindly, what they should take, if they breathe, so to speak, and have a body temperature of 37°? Definitely Omega 3 first. We don't get it from our diet, no matter what we do, if we manage it, probably with heavy metal poisoning. Accordingly, it's important, right, to supplement Omega 3. G3, of course, quite logical, especially in Germany, and even if not, how long should you really be in the sun, right? If you look into it a bit, it's a bit difficult, I'm also on board with that. I would also almost say that most people need zinc, because it's quite good for hormonal health. Fewer people know this than think it's only good for the skin. So zinc is very good for the immune system and for hormone balance. Not that it changes anything significantly. Then let's go into things that maybe not so many people know. If you're not into this mitochondrial peptide story and everything I'm deeply involved in, because it's longevity, if you're not into that, I personally think it's your duty to support mitochondrial activity as much as possible naturally. That means, our cell powerhouses, which ultimately, the worse they function, the more diseases and oxidative stress and so on they are exposed to. And the whole thing leads in the worst case to cancer and all other diseases that we have in old age. Now you have to look at it, supplements can do something from here to there, the rest is up here, but it's your duty to do this, at least. And it can also bring something, creatine. Creatine is incredibly misunderstood. I made a video a few months ago, creatine 2025 study situation, surprisingly well received. I thought it was too in-depth, and creatine is extremely good for your mitochondrial function everywhere, not just in the muscle, meaning in the brain, meaning it counteracts degenerative processes. It can counteract sleep deprivation at a higher dosage. That means you can concentrate better again despite little sleep. All of this has been relatively well studied in studies, and therefore creatine is generally, it's also suspected that it can increase oxidative capacity for the heart, similar to SLUPP332. So far, it hasn't been possible to determine that. Um, but I find it logical that it must work in some way. Creatine is an absolute game changer. I think every person without exception must take creatine. And, um, that's not dependent on what you want. Uh, if you do the whole thing, that's the minimum I see. If you're going for muscle building, so the typical dose is 0.1 g per kg of body weight, so not 3 g, but more, that's quite individual. Wait a minute. 0.1 g per kg of body weight, that means, if it's 100 kg, it's 10 g, right? Okay. Exactly. Interestingly, in the study with sleep deprivation, better concentration, and for example, also co-medication with an antidepressant, where an advantage was found with the antidepressant. Both times with, but once with creatine as well. Were they on average always around 0.2 to 0.35 per kg of body weight, so significantly more, that would be 35 g for 100 kg, that's the small ESN spoon is, I think, 5 g. Yes, heaped, I would say. Exactly, it's 5 g. That's seven heaped. That's Wow. But then we're back to the point. So creatine can do a lot, but it has to be dosed higher than what we know, and especially it has to be dosed higher than what we're allowed to say. So ESN is not allowed to write on the back, take 30 g of creatine and then you can think better after a night out. But that says, so that's what the current data says. I can say it, ESN is not allowed to. That's why you'll never get a recommendation from the manufacturer to do that. That won't happen until it's a health claim. Yes, that's crazy, because I also take significantly more than what's on the packaging. Uh, that too, I haven't taken blood values for micronutrients again yet, and I'm still at about 80% of the optimum, even though I'm at 200% Omega 3 and Vitamin D and so on. That's crazy, how silly these recommended doses are that are on the back, but that means the manufacturer is not allowed to recommend more, and then it says, take one capsule, and I know, ha, let's say, let's take three. Can you say that universally? No, not for everything. There are active ingredients like boron, for example. Boron is a testosterone booster, if you will. But it's toxic at a dose of over 10 mg, at least with long-term use. Zinc would also be a good example. You should always triple the dose of zinc. Over time, you get zinc poisoning. You notice it beforehand, though, so at some point you feel bad if you keep taking zinc. I don't know, you should stop. So, that means, different substances should not be overdosed.

Logically, they all already have some effect somewhere, and especially with creatine, it's just that we know so much by now, but we're only allowed to say very little about it, because in Germany we have this Health Claim Regulation, and it strictly regulates what we as manufacturers are allowed to say about a product, and the health claims are very limited. So, we're not allowed to make that many health claims. There are real health claims for very few products. Incidentally, it's also interesting to have influencers for this or because of this, because even if we are actually obliged to adhere to these health claims, we are naturally not controlled as strictly, and one can express a lot in the subjunctive. I used to formulate supplements for another brand. That's how I started, I was the study reader for another brand before I went to ESN, and I formulated almost all the products there for bodybuilders, to keep them healthier, but also for health. Afterwards, when I arrived at ESN, I received props for what I had done back then. They copied a lot from me. I thought that was cool. But back then, I made several attempts on the website to write a product description, using the subjunctive, with hyperlinks to studies, where I said, it's written there, and I am using the subjunctive. No, it was blocked. So, that means you're almost not allowed to say anything. You really have to be careful [clears throat], and that's the problem, and that's where I see our general problem, and that's where I also see people's sensitivity. I sometimes get accused of how I can recommend something like 5-HTP. What is 5-HTP? If you hear from someone that tryptophan helps you sleep better, then it's the case that 95% of this tryptophan is metabolized into other things. Mainly protein, the rest is not so important. 5% of it is converted to five hydroxytryptophan, 5-HTP. This, in turn, first increases serotonin and then melatonin. This helps you sleep better and makes you more relaxed. This means you fall asleep better with a delay at night. It also forms more REM sleep. In the past, this was also processed in some antidepressants, because at a higher dose, this serotonin expression can ensure that, well, that you feel better if you have a deficiency or something, a defect in the dopamine system, whatever. Accordingly, we have the link there, why can you only? It hasn't been an antidepressant for a long time now. 5-HTP can simply ensure better sleep. In Germany, probably due to the strong efforts of people who are against it, perhaps also conservative doctors, 5-HTP was put on the so-called Novel Food list. This means you are no longer allowed to sell it. 5-HTP itself, even though there are studies on how safe 5-HTP is and how good it is in a small dosage, it's always this, what if you take a hundred times the amount, yes, it's always talked down a bit, and therefore, that's what I mean, that's the problem we have, because 5-HTP is essentially similar to Trazodone in this low dosage. Trazodone, this former antidepressant, was previously used as an antidepressant. But people noticed that people sleep somehow, they become drowsy. So they thought, and somehow we want a bit more antidepressant effect and don't want them to be so tired, so they removed it. Well, doctors eventually thought, okay, where does that come from, right? And then they started prescribing it off-label for sleep problems. Investigations were carried out. Meanwhile, we have decades of quite good research on this as an off-label use, and one sees that at a low dosage, certain receptors, namely 5-HT2A and 5-HT2C, are addressed, plus histamine H1 and a bit of the adrenergic system, so everything is regulated in such a way that you simply become calmer, so you become drowsy, and then one even sees that the sleep duration is extended in the subjects and, tendentially, REM and deep sleep values are more sedative in many. While Diazepam and Co. tend to destroy your sleep, they just numb you. With Trazodone, one sees that it promotes your sleep quality, and we have decades of off-label use without negative effects. Of course, here it comes, 25 mg on average, sleep dosage, antidepressant dosage 150 to 300. That's a difference. I've never taken that much. I don't want to, either, right? So, I can't even imagine how one feels with that. So, that means we always have to go into a bit of detail, and I believe that with us, they always think and decide for the dumbest person. And I believe that's a big problem we have. And that's where the health claims come from, that's where 5-HTP is forbidden. Incidentally, you can still incorporate it into supplements by simply using the extract from which it naturally occurs, namely Griffonia Simplicifolia, you can use that with a 5-HTP content. That is then allowed again. Stupid, right? It's just stupid. But we have this example with many things. We also have it with Theanine. So you're no longer allowed to prescribe Theanine either. You're not even allowed to sell Theanine directly anymore. I don't know what's in it. So Theanine is essentially an amino acid substance that ensures that you can be calmed down. An adaptogen. It counteracts stress. But it can also promote concentration and can buffer some of the negative effects of caffeine, for example. That's why it's often used together in boosters, in pre-workout boosters, so that you don't have a crash. Or you take it before going to bed with magnesium, for example, and with melatonin, and thus have a very good natural sleep booster without Trazodone, perhaps even best with 5-HTP, and then it works great, but even Theanine is no longer allowed to be prescribed. Don't ask me why. So the Novel Food Regulation regulates that, but the reasoning is stupid. And accordingly, you have to use green tea extract standardized to EGCG. That's a very specific green tea extract, and it contains no caffeine. So it doesn't keep you awake, but it contains a large proportion of Theanine. You can sell that again. Yes, the cat-and-mouse game, the eternal one. Yes, crazy. I always have to laugh a bit internally when you talk about sleep quality, because I think, that's a total luxury problem. I have a son who is a little over two, he likes to announce himself from around one o'clock, and then he rolls through our bed and wants to fall off the foot of the bed, then I pick him up again, and so on, okay, I should improve my REM sleep phase, but above all, I should somehow get him into a bed where he sleeps properly. I would be grateful for that, but it's just that everyone has their own burden to bear, and I also understand that if you can optimize sleep, it's great. If I slept too deeply now, I would fall out of bed. That might not be the best either, but it's also a problem that time solves. But I also have that in coaching, so this, of course, being a father and so on, so these are all things where we still try to optimize wherever we can because of things like that. And where did it come from? Shift work, actually. I've dealt a lot with shift work because at some point, when I was dealing with sleep, I realized that what they're doing can't be healthy. And yes, there are studies on it, the Brain Age Gap, that's what it's called. This gap between the chronological and biological age of the brain increases incredibly when you do shift work. Mind you, at least two shifts, right? So if you just shift, and you only work at night, your body eventually gets used to it, and then you're adjusted. But this change is dangerous. And that's something where I started looking with interest at how to artificially create healthy sleep when it's needed, so that this rhythm can be maintained to some extent, so that this Brain Age Gap doesn't get so long, so that people have an earlier risk of stroke and so on. And the other thing, clearly, like time zone changes and so on, right? So, many of my clients have this, they say: "Hey, I have to stay awake all night, then the next day I have to sleep on time, or I have to go to sleep even though I was awake all day." On the one hand, you have to stay awake, Modafinil during the day, in the evening Phosphatidylserine, Melatonin, Trazodone, sleep is running, and the next day it's Frankfurt applause again, then I take a bit of this, a bit of that, a bit of that. Sounds harsh, but it works. Modafinil in general is a concentration thing. It's done quite a lot. Yes, crazy. A thousand things that come to my mind. Dear Mike, we're slowly coming to a conclusion. I have one last question that I always ask, try to embed it in the context, but it doesn't matter. If you woke up with amnesia tomorrow, and you couldn't remember anything, but I gave you a Post-it note, you could write something on it for yourself that would be relevant tomorrow. Um, what would you write on the Post-it note? Oh. That's a nice question. Thank you. [snort] Yes, well. If I've forgotten everything, I can write whatever I want on it. Yes, it could be something that helps you, because I don't know, if I forget everything next, I want to know that, then life will be better and easier. I have to answer spontaneously, to be completely honest. And I think, before I go into health and everything, I'll go into interpersonal relationships. I think I would generally go for something that is always important in life. And that would be something like, think longer about something, because that has shaped my past a lot, that I didn't do that earlier, and now I do, and it has changed a lot. Think longer about it. Yes, very exciting. Yes, I know you've had a very eventful past. I might have to revisit that at some point, maybe we should do that, because it interests me immensely. But just this whole topic has become so big already that we're sitting here for over three hours. Crazy, right? That time always flies by so incredibly fast with something like this, but it was incredibly exciting, dear Mike, thank you very much for being here. I had a lot of fun. I'm incredibly excited to see what the future holds. I'm also incredibly hooked, in the truest sense of the word, we'll have to see what's going on, what can be done, what one can do. Mike, thank you very much. Thumbs are crossed, and until next time. Thank you very, very much for the invitation, and yes, it was fun. Very, very cool. You're welcome.