REPLAY - Webinar - Reverse Physical Aging

Okay, hi. We're going to start, um, I think, a very interesting evening here. It's evening in Belgium on reversing physical aging. And let me share you my screen. Voila. So, um, it doesn't work. Okay, it works. So, this model will be, um, very special. Um, so many people have heard that, um, aging is, um, a natural phenomenon and you cannot really do much about it. You can slightly slow it down. We're going to be much more, um, let's say, enthusiastic and optimistic. Um, we're going to show that already now with the tools that we have, and it's mainly hormone and nutritional therapies. It is, um, a very good. One moment. So, um, we've heard that aging is, um, irreversible, inevitable. Well, we'll show that this really works with hormone and nutritional therapies, and it's based also on a review of the scientific literature. So, we're going to start with that, showing that really we have tools to go very far back in time if the patient is compliant, if he follows a sort of multiple hormone and nutritional therapy. And, um, much of the information I'm going to overview is, is in my textbook of reversing physical aging. And volume one goes on the head, the hair, the face, and the five senses. Very interesting, a lot of literature, 300 pages of scientific literature, but 800 pages of very practical information on how to reverse aging. And you will see it works. So, let's look at the first session of the model on reversing physical aging as model three of the evidence-based hormone therapy training program I do. And you're getting this free webinar with a lot of information on what's on in this model. And you will learn a lot of things. People do not have the money. At least with those free webinars, they will have get information that that helps them as a health professional. So, reversing physical aging with dietary, nutritional, and lifestyle therapies. Um, what is the scientific evidence? And, and I overview many aspects of how you can show that there's scientific evidence between reversing physical aging effects of hormone therapy. Let's look at the third topic, abdomen, that we overview is that there's evidence that hormone therapies can reverse atherosclerosis. This is often thought as irreversible. No, no, there it is partly, at least, are or even totally in some people reversible. You see here in growth hormone deficient men, they have actually a thicker intima-media thickness of the common cartilage. So, this neck artery, its wall widens if there's atherosclerosis, aging of the artery. And in six months' time, the growth hormone totally reverses, Zachary, this atherosclerosis. So, it really works exactly in these people. And, and the older man, uh, actually gets deprived from growth hormone and has the same efficacy with growth hormone. There are studies also that in older adults, it does reverse the aging. And we see here for, like, for example, the carotid wall thickness also in women who are taking female hormone, estrogen, and progesterone users. You see that when they use only estrogen, they have actually a thinner, um, intima-media wall, so less atherosclerosis. If they use progesterone, and these are synthetic derivatives of progesterone, it doesn't work as well, but there's still a beneficial effect. Um, now, this, um, not so good effect of progesterone that that actually decreases the good effect of estrogen, exactly due to the fact that there are synthetic derivatives. It's actually, you probably do not have this with the identical progesterone because on many other aspects of artery health, accurate possession is, is, is shows, uh, beneficial effects or at least does not take out the bad effects, the, the good effects of, uh, estrogens. And this is actually, um, um, um, my artery some years ago, uh, when I was, I would say, still young, 55 years. And, um, I, I did, I checked my current arteries. And what did I see is that actually I had a very good result, but I was on multiple hormone replacement therapy. I was also on growth hormone and IGF-1. So, I was really very cutting-edge treatment already at that time. And you see that results are good. I was on testosterone, thyroid hormones, all hormones that have beneficial effects against atherosclerosis. And you see that this is the right carotid artery, but it was even better with the left carotid artery. Intima-media was even less. So, really, really, um, good, good values. And I attributed not on a sort of genetic system that is better, but basically on the fact that I had this multiple hormone replacement therapy with nutritional supplementations.

There's also evidence that hormone therapies can lengthen the telomeres. Everybody heard now, at least everybody's in the field, about the telomeres. These are the endings of the chromosome, the red parts here on the chromosomes. And they have to have a several, a certain length for, um, the cell where they are to be able to multiply and and divide into new cells. And so, you need a few hundred nucleotides on those telomeres for it to be good. And there's an enzyme, telomerase, that can reactivate this, uh, so that it can lengthen the telomeres that shorten at each cell division normally. But this is, um, this telomerase is very poorly active or not active in most cells of our body. And, um, so when you, you see here, for example, that the telomere length of the chromosomes actually decreases. So, the endings of the chromosome decrease with age. And at 80 years, you have already a good decline in the telomeres, about 30% of the length of telomere. And that is getting too much. So, you get a sort of acceleration of aging then. So, um, well, hormones, hormones can show a beneficial effect. Let's take just estrogens. You have here mice where they have, um, knocked out the, what is called the aromatase chain, the gene that permits testosterone to convert into, well, the, that makes the enzyme that permits the testosterone to convert to estradiol. And so, it creates an estrogen deficiency in this mice. And what you see is that there's significant inhibition of telomerase in mouse ovaries, and that there's a shortening of the telomeres. Um, they get shorter because they don't have any telomeres to lengthen them. And they also have less cell proliferation in the ovaries. And when you give an estrogen replacement therapy, what you see is that it does just exactly the opposite: increase of telomerase activity, increase of the telomere length, and increase of ovarian tissue growth, more cellular multiplication. You actually have a normal development within four weeks of estrogen replacement therapy. So, you really correct the situation. So, hormones can lengthen the telomeres. There's also one on IGF-1, on testosterone, etc. studies, and we'll see this in this model.

Now, there's also, um, a fifth domain that's where there's, uh, scientific studies that show that hormone therapies can reverse physical aging. Is that these are the studies that show that hormone therapy can decrease free radicals. Because much of aging is due actually to free radical damage. And you see, for example, the free radical status in controls is this. And in growth hormone deficient adults, actually, you see that they have about two to three times more free radicals. And it partly normalizes or improves, at least, with growth hormone treatment. So, basically, that shows also an effect. And there are many other hormones. Estradiol is a very potent antioxidant, for example, and has also very good action. DHEA, partly. And, and testosterone, not so much. But cortisol is also an antioxidant.

Now, there is also evidence that showed that hormone therapy can increase lifespan. And that shows also sort of reversing physical aging effect, or at least the slowing down of aging effect. And, um, now, for one reason or another, uh, most studies prefer to talk about mortality than about longevity. It's not serious to talk about longevity, but it is, it is serious. Okay. So, most studies, you find information on mortality, hormone therapies, and hormone intervention that actually, um, decrease mortality. That means that they extend lifespan. And here's one of the studies. In, um, very, um, not a very representative study, but it does trigger something in your mind is that when you give sex hormones after breast cancer in women, they actually have a much lower mortality. That decreased by 60 to 80 percent less. And that's what this shows. If you take estrogens, then you have the most. If you take just testosterone, you have already a very impressive improvement. Other studies are not so dramatically, uh, with a dramatic improvement, but still they do show a 30 to 50 percent decrease in recurrence of breast cancer and a mortality decrease of about 20 to 30 percent. So, we actually have an abundant list of peer-reviewed scientific publications that show, uh, that support and show reversing aging effects of hormone therapies. And how much years back in time you can age, it's not so easy to determine. There are some ways, and it will be explained how to determine by determining the body composition and many other, um, I would say, uh, parameters that permit, uh, uh, you to have a relatively good idea how much years you go back in time. I do have patients that can say they have reversed more than 10 years, uh, with this, this parameters measurement. Now, we must still keep our eyes on the ultimate goal of medicine. I believe this goal may be approached, at least within 20 to 30 years, is to totally reverse the aging of a person of 70 years back to something like 35 years. Okay, looks now still premature to think about, but if we can already reverse 5, 10, 15 years, why wouldn't we reverse more back in time? So, let's achieve that goal. Then, when you have this goal, you always want to get new information and to include new fundamental information in your practice so that you can treat your patient better. So, also the question important to answer is, what is health? Health is reflected by an energetic and young adult physical appearance. You need to look younger. Actually, that's actually a, a good idea, or that reflects well if you have a better health. And so, when you look at people here, you have children that grow up, and they grow to be adults, and healthy young adults. Most of, uh, those children grow to be young healthy adults. But when the adult ages, there's an increasingly less healthy state with advancing age. And if you treat with hormones, you get a decrease in these, in this aging. We are not yet being able to totally stop aging, of course. In the beginning, you reverse aging a certain time, and so it looks better. But, but basically, we need to go to that goal that we keep our patient as healthy as possible. And that is a young healthy adult. You should look like a 25 to 30, 35-year-old.

So, let's look at the dietary and nutritional supplementations that reverse physical aging. You see that I specifically talk about supplementations and what I mean by this is not therapies. Because what I mean with this is that supplementation is actually correcting a deficiency or optimizing a level. And, and so it has a base. If you have a person with high levels of, for example, zinc, and, and very high levels, why would you give zinc? So, it's really is to optimize the situation and not, not just overdose. And, well, for example, with eating, if you eat fruits, it may decrease wrinkles. This is a study done in older adults in, uh, the Netherlands. And they checked about fruits, and they checked the wrinkles that they measured by photographs. They took the photographs of the face and they tried to see how much area of the face had wrinkles. And basically, what we see here is that women who had a high fruit intake had significantly fewer facial wrinkles, and women with low fruit intake in the lower quartile had actually significant more facial wrinkles. So, imagine just this. We always think that hormones can't do everything. No, you need also to have good food. And there was no association in men. It was really associated that was found in women. Also, eating, eating gluten-free foods may, may decrease gray hair. Acrylic disinformation is only based on anecdotal cases. I've, I showed two studies of anecdotal cases of individuals having lost their dark hair, for example. As this person in her 30s, she lost all her dark hair, and they became completely snow white. Like here, at age 43, it's not the patient here, it's just the picture to show white hair. As at age 43, she looked like that. And after a few, when she was put on a gluten-free diet, at age 58, so much later, 15 years later, after a few weeks, her hair grew out darker. And by the age of 63, so five years later, her hair was markedly darker and similar to the hair of the first patient. That was the other anecdote case was talking. So, he still has some gray hair, but actually much less than before. [Music] So, gluten-rich foods, not good. Avoid snacks, because snacks could give wrinkles. Here's again the Rotterdam study that we saw. And these are snacks, and they're usually carbs. And what we see is that one with the low snack intake has significantly fewer facial wrinkles. Accurate carbs and, and snacks give a digestive unrest, and wrinkles are reflected by belly that is actually bloating and, and not a good state. There's a sort of irritation of intestines in people who eat snacks, and, and that will give more wrinkles. The face reflects the belly, actually. If your face is bloated, you often have a bloated belly. And that's also explained in, uh, this, uh, model. So, one with high snack intake has significantly more facial wrinkles, as you see. Is this woman here? And again, no association found in men. So, typical for women. But I suppose that men who eat very badly and a lot of snacks will probably have some problem.

And nutrients, nutrients can also decrease wrinkles. Here, for example, vitamin A. Uh, you give to old adults, 87 years, and you put on the skin of the arms that is wrinkled at that age in most of those individuals. And you put a topical vitamin A lotion on the right or left arm. And what you see is that there's significantly decrease in fine wrinkling scores of the skin of the arm. There's also higher amounts in the skin of aminoglycan, which is actually, um, a compound that retains substantial water. So, the, the skin looks more dehydrated because of lack of glycosaminoglycan at that age. And this is increased with topical vitamin A. And there's also more procollagen one, so you have more collagen fibers in the skin with vitamin A. So, it does decrease fine wrinkling. And the synthetic vitamin A, that's a little toxic. So, you still need to be careful. But if you put it locally, there's less problems than when you take it by mouth. And this retinol, retinoid, is even stronger than the retinol cream to decrease wrinkles. You have less facial wrinkles in South Korean women. And the wrinkle that was also decreased, and the area of the, the wrinkle area was also decreased in proposed compared to a retinol cream. But, you know, this, that's it. The natural vitamin A. This is the synthetic one. And you see that there's also an improvement of visual wrinkle and maximum roughness, uh, and that there's also an increase of dermal distance and dermal thickness. Derm is thicker in these patients with synthetic vitamin A. That all decrease the facial wrinkles. And there are some nutrients that can decrease gray hair. And not just one. You see, for example, a study with PABA, para-aminobenzoic acid, in patients who had gray hair and various clinical disorders like dermatitis and scleroderma. That's an indication to take PABA in high amounts. They took really large amounts, uh, 12 to 24 grams per day. And actually, they were, um, in, in those who respond by getting darker hair. That wasn't the focus. The focus was getting less dermatitis, less scleroderma. But those that improved, the first one to improve was after six weeks. It began to get darker hair. And the darkening of gray hair was observed in actually one-fourth of the individuals, five of 20 individuals. Very old study of 1950, and merits an update.

And nutritional deficiencies that can cause gray hairs. First of all, copper. The fish, if you're too low in copper, get a gray hair. But it's often a curling hair that's typical for copper deficiency. And if it's a problem of the fish, it's gray, but more whitish hair. Um, and if it's zinc, the fish, it's a gray hair that can be dry, rough hair, and brittle at the broken ends. And valine and tyrosine deficiencies are suspected also giving gray hair because they can reverse vitiligo, the, the white spots we have on our skin. So, and then in that case, it's a gray pigment pore hair. And for each deficiency, we talk in this model more profoundly. So, you get more details, you get to know the doses that need to be given. Here are biotin deficiencies. You can also give your hair, but then you have a twisted, torted, uh, hair. It's stiff hair, very difficult to comb. Gray hair can also come with cysteine and methionine deficiencies, that they contain sulfur, and that lack of sulfur may give gray hair, thin, fragile, and flat hair. When we beat with the several studies shown that vitamin B12 administration, sometimes even in mesotherapy, but also just systemically, can decrease gray hair. It's a gray hair in that case, there's pigment poor hair, there's vitamin B12 deficiency. And also, there has been documented that omega-6 polyunsaturated fatty acids, if you put that on hair that is gray, it may make the hair less gray, especially in young adults or young children that have, actually, gray hair. Putting on the head may help, really. And they probably develop gray hair due to an omega-6 polyunsaturated fatty acid deficiency. So, you see, there's overviews in these models, but also in other words, you get overviews of what are the deficiencies and what type of hair loss or gray hair, whatever may happen.

So, nutrients that decrease dry eyes will be also discussed. There are several of those. And let's look at a nutrient that can drastically improve body composition. A very safe nutrient, and that's L-carnitine. Just one month, see what it gives in older adults. Here, for example, in older adults, after one month, there's an of four grams a day, two times two grams of L-carnitine. It's not even the activated form. Acetyl-L-carnitine is the basic form that is, let's say, cheap. Two times two grams per day of L-carnitine gave, uh, two kilos more of muscle mass and about 3.5 kilos less of fat loss. What a change! So, I have here under my desk, actually, L-carnitine. I take it in the morning, and I take it later in the day. Um, also, it decreases 40% of physical fatigue and 45% the mental fatigue. It is used in many patients who have, um, cancer and seem not to recover. Maybe it's also a way to give it to people who have COVID-19 and no, don't recover well, because it will make them more energetic. And I can tell that I have more energy by taking L-carnitine.

Additional compounds to reverse aging will be seen in this first session, like telomere activators, astragalus extracts that improve the skin. After 12 weeks, you see an increase in skin firmness that can almost double the skin firmness after 12 weeks. And there's also the crow's feet wrinkles here on the corner of the eyes that are 18% decreased, and there's a 9% decrease in skin redness after 12 weeks. And so, basically, it really rejuvenates the skin. And epithalamin, epithelon, is a peptide that we make actually in our brain, in the pineal gland. And this epithelon can also activate the telomerase. You see here, this is the picture that you get with untreated fetal fibroblasts. And actually, at every point, represents, um, telomeres. And you see that there's much more telomere, telomeres, um, so endings of chromosomes, uh, they're longer. There's more telomere staining, longer telomeres. It means when these, uh, fibroblasts are treated with epithelon, very safe substance, it is also very anti-cancer in many animal studies. So, I, I think it's, it's something that is worth it. It's sold as a nutritional supplement in, um, in, in Russia now.

Another chapter that we'll see in this model will be the pollutants. They can cause premature aging. And air pollution, in and outdoors, can increase physical aging. So, it's not only outdoor pollution, but it's also indoor. All the plastics, all the furniture, when you have a smell inside a home, you have books, you're actually smelling, you're inhaling toxins. And 10% of our pollution problem is probably outdoors, unless you really live in a very unhealthy neighborhood. But 90% of our pollution is indoors. So, we'll talk about that. Yeah, some of the references are here. Let's give an example, just tobacco. If you're smoking inside, this is a person who smoked during 17 years, and her twin sister did not smoke. They look a little bit similar, but when you look closely, they're not similar. The one is looks older. You see here, for example, swollen lower eyelids, uh, that she has here, while she doesn't have, are almost not here. And then she has upper and lower lip wrinkles, like here, that the other doesn't have. They have the same genetic pattern, but one is smoking. So, pollutants and particular aging. There's references. Uh, we also see some information on physical exercise. I won't go into details because you cannot see everything now.

And the second session of this model on reversing physical aging is really important because that's sort of you start with hormone therapies. Here, if you want to learn about unknown therapies, you want to start, you have basic information, but exactly information that is linked to reversing physical aging as an additional effect than improving the health of the person. So, the question is always, can reverse aging 10 to 25 years back in time with hormone therapies? Well, if we can do it, it, you first have to give to your patient basic hormone therapies. And in the second step, you generally go to subcutaneous hormone injection containing several hormones that give an additional effect and very potent effect. But you often have to start with some basic hormone therapies. So, you make things safe, and you build your treatment on a strong basis. And then the third, if it doesn't work enough with all these treatments, you have to put locally the treatment, topical hormone treatments. So, let's look now, and that's the topic of the first, the second session of the model on reversing physical aging. Basic hormone therapies. Basic hormone therapy, the thyroid, there's vasopressin, there's a sex hormones, and those have the most visual reversing aging effects of those basic hormone therapies. Then, there's the adrenal hormones like cortisol, DHEA, aldosterone, have less visible effect, but are still quite important in, in the task. And each hormone treatment will be seen separately. But there's, um, we will see for each, and generally the mechanism of action, how it can reverse aging, how it works on the skin or the muscles, on the fat mass. And then we'll see with physical signs of deficiency. We'll often have an example of lab tests, so that you can learn to interpret lab tests and see how you can decide on a treatment also based on lab tests, and not only on the clinical features. And, um, we'll talk about what are the best preparations, actually, in this aspect, that most efficient, and what are the doses to get doses. And then the treatment results will show a speech before and after. Sometimes it's a synthetic picture where a patient has been rejuvenated, so you can compare. And, and there I show what aspects there is improved that normally the hormone treatment should give. And, um, there's also, we will also see some studies. There will be also often additional treatment tips, these things that really make a difference that you need to know when you treat. And then some scientific references. And you generally have to think, you get lots of practical information to get started.

Diary treatment. Let's look as first, the most used thyroid treatments in reversing physical aging is this get a thyroid. So, you have all the thyroid hormones, not only T4, but T3, T2, T1, and T0. It really has a more persistent effect and more, uh, physical effect. And then you have the synthetic T3 and T4. And, uh, so always combined with T3, those work the best. We'll have, of course, a whole model on thyroid therapy. We'll talk about, uh, thyroxine or lung treatment, three alone treatment. But what really works on reversing physical aging are those two types of treatment. And then you have, for example, this patient being rejuvenated with, for example, thyroid therapy. And in this rejuvenation, there's less diffuse hair loss all over the head. The hair is less dry with the thyroid hormones, not dry anymore. And there's a sort of regrowth of the outer third of the eyebrow that can come. And then especially less swelling of the eyelids. You see swelling of the eyelids, less swelling, thanks to thyroid hormone. And less dry skin in general. That is the aspect what thyroid hormones will give. And also, it will give a sort of slimming effect. You see, for example, this patient having untreated thyroid deficiency. This is with thyroid therapy. You see that there's less suborbital edema. But she's also globally has lost weight, and she looks slimmer. So, does references that support this type of treatment effects on obesity?

And let's look then on a second type of treatment that we'll discuss in this model, the vasopressin. The hormone that is anti-diuretic. And usually, it's a synthetic derivative called desmopressin that is used. What can it do to reverse physical aging? Well, and again, I will say that we're giving hormone treatments to correct the deficiency. We're not giving it just to rejuvenate. That's just an additional effect that can come. But basically, if we give it, it's because there's a deficiency. And there are many other complaints of deficiency that will be corrected with the treatment. So, desmopressin, you can get that in tablets or in solution. I would propose you to take tablets because they're easier, and you can let them melt on the tongue. They melt easy, and then they're very efficient. So, this vasopressin is a key hormone to improve very small skin folds that you can find on the skin, sunken eyes, and the tongue with two indentations. So, the tongue that has little borders. This is an example, for example. You have here the crow's feet wrinkles here, and small little folds over. And that's vasopressin deficiency. And with desmopressin, when you give it, they disappear. That's the sort of efficacy that we have. Now, among the treatment tips that, um, I can give to keep a better level of vasopressin is go to time on bed. A study here showed that when adults were exposed to bright light up to two o'clock in the morning, they had less production of vasopressin and thus lower levels. So, if you go on time to bed, you sleep enough, it's better for your facial presence.

Now, what about female hormone treatment? Well, there are several types. There's transdermal estradiol, or there's oral and vaginal progesterone. Transdermal liposomal shell. These are the two best ones. So, you have oral estrogens also. You have injections of association patches. But the transdermal estradiol gel is actually generally the the best. And the oral or vaginal progesterone are actually the the most handy to work with and often efficient, uh, for you to work with, uh, in your patients. But I will give in this model several information. One of those information is that transdermal estradiol decreases fat mass, while oral estradiol is better than placebo, but cannot really halt the progressive increase in fat in women with age. And you see that lean mass is also improved with transdermal estradiol, while not much in placebo, and certainly not with oral. So, meaning that if you want to reverse physical aging of your patient, you need to do it with transdermal estradiol in a female patient, and not oral estradiol. Studies showing that there is a, an association of muscle loss with low estradiol and improved estradiol treatment are here. And you can see also the body mass is improved with estradiol.

Now, let's look at a lab test. And we'll show you how we, you will learn to interpret lab tests. This is a woman of 53 years old. Her skin is thinning. She complains of irregular menstruation. So, she still has menstruation. And she, she had a blood test seven days before a menstruation. And FSH was high, uh, and serum estradiol was 85 pg/mL, which is low. Estrone was also low. And SHBG is also low. The sex hormone-binding globulin that transports estrogens throughout the blood. And serum progesterone is also low. And so, when you look at what an optimal level is, you should have a lower than 7 FSH. And it's 21 at that time. Estradiol should be under 50, and it's 85. And estrone should be 120, and it's 65. So, basically, these lab tests show estrogen deficiency. And when you look at SHBG, it should be higher. That shows that there's more association. The higher estrogens are, the higher SHBG is. So, it's a, and progesterone would be 12, 15. It's two and a half. It's too low. So, she doesn't ovulate well. It doesn't make progesterone. She doesn't even ovulate. Problem. Um, so, this you need to manage. And you need to give female hormones, like I showed before, that type of hormones. And we'll talk how in the cycle you have to do that. And so, if you give a female hormone treatment, you can make this person look younger. In the beginning, and you see, what it will do is that there will be less vertex hair loss on top of the head. Loss will be thicker hair, more hair volume. That's typical for estrogen. You can almost double the volume in a woman who's estrogen deficient. Then she receives estrogen. You can sometimes really double the volume. Um, there's more humid eyes, and there's also more colored face, not so pale anymore. It looks also younger, and less dry and skin with more skin elasticity. That's what suicides can do.

What can testosterone treatment do? And we'll look at testosterone treatment in men and women. Well, basically, in men, it will be a transdermal liposomal cream of 10% that needs to be given. And testosterone enanthate injections, uh, are an alternative. And the cells in the candidate and shakes, we'll see about the frequency, which doesn't always match what is proposed in the flyer of the medication. Often, it's too long periods that they propose. And then the person is one week or two weeks or even nights a month with the, the bigger injections in deficiency. But we'll talk that in detail. Let's look at, at women. You see that, um, it's been shown that in women, the higher their testosterone level is, the more lean mass they have. And most of lean mass is muscle mass. So, the more muscles they have. So, higher serum testosterone, higher lean mass. It's really a positive correlation. But also other body composition. The highest testosterone was, the lower the body fat was, and the weight was. This is a, a study where they give female hormone conjugate estrogens with testosterone. Methyl testosterone. And what you saw, and that exactly in red, exactly that there was a more lean body mass, and there was also [Music] less fat mass with muscles. Basically, uh, was it was better. There was also more lower body strength, etc. So, basically, the results are good to give testosterone to women with female hormones. In men, this is typical, uh, a man who's always been deficient in testosterone. He's still young, but he has muscle hypertrophy and, and doesn't have any body hair. And, and does look very masculine because of the lack of testosterone. So, this man actually needs to have testosterone. Even today, there was a patient in one of my doctor's work with me where we discussed about how to improve his situation because he looked like that. The physical signs in men when they're older can be an abdominal fat and small breast formation, gynecomastia or, or pseudogynecomastia. Is fat, organic fatty belly, abdominal obesity, muscle hypertrophy. And you see also that you can have a reversal. If you look on the left, that's actually typical of low testosterone with, um, and, and, um, you have normally with testosterone, you get thicker inner eyebrows, more humid eyes, more, uh, humid eyes, more color in the face, younger, firmer face, and less dry skin and firmer muscles. You see that the face looks firmer. That's typical with testosterone. And here are references in women and, and in men, always muscles and masculinity, etc. So, there's more than enough reference. Again, a tip for testosterone treatment. Very important because some treatments may not work well, at least to build up the muscles, is that you need to eat meat, fish, poultry, protein-rich foods for testosterone treatment to give better muscles. If there's no, not enough, you, there won't be any improvement in muscle mass. Avoid drinking alcohol at least every day. Wouldn't be good. Not more than two days a week, or you will really impair the treatment.

Now, let's look at another treatment that is basic commentary. Cortisol and glucocorticoid treatment. And we always think that cortisol is the devil or something wrong. No, it's something in our body. Without this hormone, we're dead within 24 hours. So, we need it. And when there's a deficiency, we suffer. And in aging, part of aging is also due to cortisol deficiency. For example, this person, very old, 117 years, she's very cortisol deficient. There are hyperpigmentation spots, this Addison's disease, and hollow face. So, certainly low in cortisol, too low. And you see that elderly persons actually produce less cortisol secretion, 25 to 30% less. They can have high levels in blood because it doesn't penetrate in target cells. It's not really a good picture. And you see many, um, physical signs of aging are related to lower cortisol levels, like pigmentation, mucosal pigmentation, skin pigmentation, tongue pigmented, pigmented elbows, knees, palmar creases, pigmented scars. And, and then the opposite, vitiligo, depigmentation can be linked to lower cortisol levels. And also a thinness, a lower body weight, cachexia, associates with lower cortisol levels. Obesity, even can also be caused relatedness, lower cortisol levels. There are at least nine studies showing that. And, and abdominal obesity, two studies showing association with low cortisol levels. So, basically, why would you get thin and why would you get fat when there's not enough cortisol? Well, you get thin because you have an inflammation in your intestines, you don't absorb well because of this inflammation, or you just don't have any appetite because of low cortisol. But some people have low sugar levels, very low sugar levels with cortisol, and then they have sugar cravings, and they eat too much sweet food, and then they can get obese. That's how you can have both different types in, in patients. There's, of course, also basically associated with high cortisol levels. So, it's, um, you need to, to check accurately your patient before treating to be sure, uh, to have the right diagnosis.

Now, also a tip here is to go on time to bed to preserve cortisol. Like for vasopressin, a same study showed that accurately, there was a lower 24-hour on 24 cortisol concentration if the people slept not enough, and especially if they went too late to bed. Though the hours before midnight may count double because you have more cortisol. Aldosterone treatment will be also seen in details, but we won't talk about this. But it's, it keeps your blood pressure high. Aldosterone, if it's too low, you probably need some aldosterone.

Now, the second session will go on reversing physical aging with subcutaneous injections that combine multiple hormones. And growth hormone, IGF-1 is the first category. Insulin is one of those that can be, and that's the big three. Those can have major effects. I mean, you can really see that the patient looks younger with these treatments, feels much better, of course, because the reason again, I repeat, that we give is to correct the deficiency. And, um, so we also have relaxin, an MSH, melanocyte-stimulating hormone, that may be applied. And for each subcutaneous hormone treatment, we have the same overview. We're going to look at mechanism of action, physical signs of aging of deficiency, often an example of lab test, most used preparations, what are, how does the patient look after treatment, before and after pictures, additional treatment tips, and scientific references, and lots of practical information. So, let's look at some of those information. Here's growth hormone vials that are used for, um, combined hormone treatment, reversing aging. Most of these cartridges that are put in pens are about 1.5 milliliters, but you can have different concentrations. Here are different panels with different concentrations. Um, now, mostly in a vial of 1.5 milliliters, if they give one click, it's a certain amount. But it's basically, there are 100 clicks per cartridge. That means once you did 100 clicks, if you do 25 clicks per day, in four days, you have finished your vial. Okay? And one click is done 0.05 milliliters for you to know. So, also references with growth hormone, muscle mass, and lean body mass. And then how it does, what happens when there's growth hormone deficiency, and what happens with growth hormone treatment.

Let's look at one case of an older male, whereas like here, with muscle loss and sagging skin. His serum IGF-1 is 270 mg/L, which looks acceptable because you see the optimal man is 300. So, why not? Maybe it's acceptable. But he looks a little bit bigger. So, maybe he had more before. Bigger persons have higher levels. But yes, the ratio of IGFBP-3 on IGF-1 is lower. And this ratio should be actually better. There's less bio-available. And the urine of 24 hours actually are two. So, it's too low. So, basically, he has lower growth hormone and he has less bio-available IGF-1 going into the target cells. So, it's too low. The reason is, this is IGFBP-3 that transports IGF-1. That's a binding protein that transports it to the target cells. Is too high. When it's high, it keeps the hormone in the blood. It doesn't go into target cells. So, the reason is not that this is low, the reason is this is too high. And that's why he has an IGF-1 deficiency or growth hormone deficiency because growth hormone increases IGF-1. And so, low IGF-1 means low growth hormone activity.

So, let's look about what IGF-1 treatment can give. Usually, you have IGF-1, uh, in, in the states, more like a peptide, long-acting IGF-1. It's a synthetic derivative, IGF-1. It's about 10 times more potent than the IGF-1 that is bought in pharmacies in Europe. And you see that IGF-1 reverses physical aging. And she looks younger. The, the sagging cheeks here is not anymore there. This gives you an idea of what it could do. It's a synthetic picture. It's not a picture of before and after IGF-1. But it gives you an idea of what IGF-1 can do. And so, basically, what I do with my patients when they have those both treatments, in, I try to make it simple for them, not to have to make several injections. And so, I can give growth hormone in a vial cartridge, and we put also IGF-1. And that will explain how to do it, how to, to do it professionally, so that you can explain to your patient to do it well. So, we have a combination of growth hormone and IGF-1. And the ratios can differ following what the patient needs as a treatment, because there are differences between growth hormone and IGF-1. And that will be explained how you can discriminate the difference.

And so, what about insulin treatment? Well, you see a culture of human fibroblasts. And these cultures, when they give insulin, the insulin will increase in these cells. These are the fibroblasts that you see here. They will absorb the amino acids that are put in medium quicker with insulin. And this is fundamental, making a big difference. Some people do not respond to treatments because they are too low in insulin, and they cannot absorb amino acids and put them in the muscle cells, for example. So, we'll explain how to discriminate this situation. In the model, here, in conscious cachexia, for example, 50% of cancer patients have that cachexia during treatment. And when they die, they almost all die with cachexia. Well, those who have high serum insulin levels resist better, and they have a, they have a better heart support. And when they receive insulin therapy, it preserves muscle tissue and feeds the host rather than the tumor. So, it will not activate the tumor by giving insulin because cancer patients die when they get emaciated in cachexia. So, this you could counter with insulin. This is a patient with low insulin. You see, it looks thin, the neck, poorly developed muscles, thin arms, etc., thin legs. And here is the difference. You see the normalization of fat and muscle mass, larger arms, larger pelvis. So, you see a big difference, just insulin. And this is before and after. That's one of the first pictures when insulin was given in the 1920s. You see how the face gets fuller. And here, emaciated, same person, emaciated, completely too thin. And see how the buttocks are improved, and the whole body is improved. What a change! An insulin treatment is also used in bodybuilding. We'll talk about that. Bodybuilders, you do doping, use insulin as an anabolic to increase muscle mass. I will talk about the doses that they, they take, etc.

Here's another treatment, MSH, or melatonin one or melatonin two. And one interesting is that this mouse is staying horrendous. It gives you more color and improves also your sexuality quite a lot more than other hormones. Actually, has some effect because it boosts the levels of other hormones. It decreases the growth hormone and thus increases also the IGF-1 levels. It can increase testosterone levels or the effects of testosterone on sebum glands. They are harder. You will have small stronger with both together. It also increases estradiol effect because it stimulates irritates activities, certainly cells of men. So, you get higher estradiol also, which is good for the hair, but may not be too much. Relaxin. Relaxin deficient skin. Old adults look like this. We make relaxin. Ah, that's the sort of pregnancy, or one you have a rigid skin when it's too low, like here. And it reverses skin and muscle wasting. You see that in the pregnancy, there's so the pregnancy glow and elasticity of the belly skin and muscles. Relaxin, it really remodels the pelvis and cervix will dilate. But it also increases skin elasticity, and that is interesting for us. It also increased the microcirculation [Music] by inducing nitric oxide. Now, let's think, when you have a chronic problem in the place of your body, the main reason is there's not enough microcirculation. Meaning you, the capillaries around the organs are not open enough. And relaxin can open them up. Vitamin C can do that also. And, but, but this is a major, uh, effect. The pregnancy glow is also an increase of the capillaries of the skin. And so, in scleroderma, that is a skin that gets very rigid, and, and aging people get a more rigid skin. And basically, this relaxin can reverse the scleroderma. And in, there was a study that went on, and at the end, 42% of patients actually had improvement on the global score of skin. They had a less thick skin, less fibrosis in the skin. And there was mostly an improvement in the skin of the chest, the forearms, and the hands. Results is that this person looks like we saw before, this synthetic picture that we get. You see, they get sort of rejuvenation. Well, relaxin would give you this long younger face, and will get less sagging cheeks, more anesthetic skin. So, you get firmer face, less nasolabial folds, and less skin folds under the chin, and the younger skin, and less, and more skin elasticity, and less stretch marks, actually. So, basically, interesting treatment, but problem is very difficult to get for the moment.

So, basically, when you have all these treatments, when you have your patient, the best is to give a sort of basic hormone therapies. And then a second phase to give a combination of hormone injections that result. And then you have this sort of global effect that you see on the face of this man. Third type of treatment is when it doesn't work enough in some places, you need to get to apply the hormones locally, either by cream or injecting them locally. So, let's look at what melatonin can do among all the different options that we have. Well, melatonin incredibly can really increase the collagen deposition in the skin. You know, it can decrease it. You see that when you take out the pineal gland in rats, they get a very thick skin, they get scleroderma, actually. This is all fibrous tissue. And this is the result with melatonin. You decrease the skin fibrosis. That's a rejuvenation effect, and also an anti-inflammatory effect of melatonin. So, this markedly decreased skin collagen accumulation, and, and you reduce the effects of the pineal gland on the skin. This is real pictures in patients. There's a combination of vitamin C and melatonin. And you see that after five years, this patient doesn't look older, and looks actually, the skin is basically some younger and still tight. So, we'll look about what type of prescriptions for topical hormones to reverse skin aging. And we'll also talk about giving mesotherapy, a lot of small injections in the face. And will give you formulas how to work with. In this model on reversing aging with subcutaneous injection are topical treatments of with hormones.

Now, let's add a fourth session that is really may, uh, surprise you how far this type of medicine can be for preserving our eyesight, our hearing, and other senses like our taste and our smell, and the touch. So, let's look at first, reversing the

The aging of vision. We'll look at three aspects: presbyopia, not being able to read well; glaucoma; and age-related macular degeneration.

So, presbyopia. There's my, um, reversing physical aging textbook. There's much more information, much more different pathologies of the eyes, so it's really in and and related with aging or even not like written into these pigmentosa and what you can do. Really interesting.

And so, presbyopia, um, you can already preserve your eyesight partly through, um, some lifestyle factors. And one of those factors is the temperature. If you live in an area like Ecuador, you have two options: you live either in the mountains or you live by the sea. And in the mountains, you have a colder temperature, and there's also more exposure to ultraviolet light, which is not good for presbyopia. But actually, the temperature is, is important. And those people there have problems with reading, most of them around age 42 and a half. But when you go in the coast area of Ecuador, near the beaches, you actually have a warmer temperature, 12 degrees or 12 and a half degrees Celsius warmer, and 33 degrees Fahrenheit warmer. And basically, presbyopia starts there at a younger age, below 40 years, so there's about three years sooner presbyopia where the average temperature is higher. So that's maybe not a good effect of living in a warmer climate. And we'll explain why with experience on rabbits, etc., so that you really, you know it.

And, um, presbyopia, what about nutritional deficiency and supplementation? Well, um, there are, um, a whole series that can help, but I will explain them in the model. We, we might run out of time otherwise. Here, uh, here's just to show you that among the hormones, there are children with growth hormone deficiency who have hypermetropia. It's the presbyopia of young, uh, children. And, um, and that is corrected with growth hormone. So growth hormone seems to correct that. So why wouldn't it not break the presbyopia? And, um, presbyopia on hormone supplementation. If you have to give hormones to places, we will look at all the studies that show effects. But this is more or less the doses of female hormones that you need to give. Male hormones to women. This is the dose you need to give for men. Actually, either you give a transdermal preparation or an injectable. This is about the doses that are efficient to delay or decrease the impact of presbyopia. And this is the dose for insulin for diabetics that may help. But then diabetics, it was real diabetes. And, and melatonin. This is the dose that may help. But there's also a solution in drops that you could put in the eye that may help. But we'll talk about that in more detail. So it gives you, you have for every, um, hormone, for every hormone, nutritional, you have sort of overview tables like this. I'm showing with this picture of a person, and then you have different types of treatments that can be given and that are active. So we all have a sort of summary overview of what we just said, so that you can really get into your mind, uh, what will be helpful. You see also, you have here hormone mesotherapy there that can be given by vasodilators and hormones. And we'll talk about what type of hormones and vasodilators to give. But when you inject all over the face these products, you actually have a better vision. And there's a stellar chart that you see when you go to the ophthalmologist. You see, you have a Snellen chart where you can see from far, and you can see then lines, each time lower and lower lines. And if, well, they usually see two rows lower, which is fantastic. I had a patient that just was able to see, I wouldn't, I didn't even believe it myself, but she just saw three letters and then suddenly three lines lower, she could see very clearly things. So you sometimes have very spectacular effects that keep on because when she came back, but six months later, and she didn't do anything between, so one line, well, one line on the Jaeger chart, that's for near vision. Lower, and two to three months later, you have done, uh, again, a slight improvement extra. And four or six months later, you have been improved. Of course, these treatments work that you give in mesotherapy with the hormones. If you take also from the inside, the same hormones. So you have inside and outside, and that is really how it works. Well, otherwise, you don't get so good effects.

Glaucoma. How to reverse it? You see that coffee actually can increase by two millimeters of mercury the intraocular pressure, which is a lot. You know, the intraocular pressure is usually between 10 and 20. If it's above 21, you get, um, it's excessive hypertension. And if you increase, for example, from 15 to 17, or from 20 to 22, it can make the difference. So stop drinking caffeinated coffee if you have, um. And so you see that if you have two cups of coffee, in some people, it can increase seven millimeters mercury. So if you're even at 15, which is the average of a police, you go to 22, you're in, in the glaucoma range where there's hypertension in the eye. So it's really in. It's not the coffee, the caffeine. So I was wrong to say, you decaffeinate coffee, because it's some other coffee extracts that increase the pressure. Probably the fact that you burn those coffee beans make that it gets a little toxic, and that seems, following the researchers, to be the reason why eye pressure increases. It's like a reaction of inflammation to those toxins.

Also, in glaucoma, low magnesium, B1, vitamin B1, and C are related with glaucoma. The average level is about 20-30% lower of these nutrients. So, might come into. We know that low magnesium levels can give temporary vision defects by vasospasm of the arteries that go to the eye. And there's also, um, studies, and we'll see those studies, where this low vitamin A, zinc, manganese, iron, omega-3, polyphenol fatty acids. So we'll look at some of that literature.

Glaucoma is also related to hormone levels. And typically, the first thing to think of is hypothyroidism, low thyroid function. And you see all these people there are swollen faces and have low thyroid function. And on the average, a hypothyroid patient has four millimeters of mercury high intraocular pressure. That's too much. And the reason is, especially chronic open-angle glaucoma, we'll explain what it is in the model. Well, 16 to 22% of patients with hypothyroidism have this sort of glaucoma. That's a lot. And, so the reason is, of course, there's myxedema in hypothyroidism, and those mucopolysaccharides pile up also inside of the eye and decrease the evacuation of the fluid that is in the eye. So basically, diet may help to decrease glaucoma. Also sex hormones, there are studies on that, and we'll show some of the references. Melatonin also. And these are more or less the sort of doses for treatment of treatment. You should give. Pregnenolone seems also to have some effect, and growth hormone and IGF-1. And then to avoid or to take lower doses of glucocorticoids, although it's, it's not the hydrocortisone, it's mostly with synthetic derivatives that you have the problem. And you have to add when you give a cortisol, always DHEA that protects also against cataract of the eye and other things. So here you have to associate with female hormones and glaucoma. And, and showing that actually female hormones are protective. Estradiol protects even the cells from damage when there's high pressure. So basically, that's interesting.

Now, what about age-related macular degeneration? This is how a person looks like. That's the vision with age-related macular degeneration. You see here, um, it's an eye disease, actually, of the macula, the central portion of the retina. This is the retina when you look inside of the eye. And you see that with aging, there's an increased risk of macular degeneration. Actually, individuals at age 75 have more than 30% have age-related macular degeneration. I've done genetic tests, and I'm very plus plus plus for the two genes that are polygenic proliferations that promote macular degeneration. So I'll see if I can avoid it by having good hormone nutritional treatment. Let's do a meeting in on 63. In 12 years' time, to see if it works. If it works as well as for my arteries, my car arteries, why wouldn't it work as well for my eyes? The majority of people with macular degeneration have an early form of the condition, experience minimal visual loss. But some have more progressive ones. And that's why we need to be careful. And certainly, people like me who have genetic polymorphisms, they have to be even more careful. So we know that blue eyes have two times more risk of progression of age-related macular degeneration, progression to a wet form, which is the dangerous form. I have blue eyes. Okay, another reason for me to be especially careful with my eyes. And one of the treatments that can help is nutritional supplementation, for example, lutein. 12 months of 10 milligrams per day of lutein can really be helpful. You see here, you have an improvement of more letters that you can read on a Snellen chart from far when you take, during 12 months, 10 milligrams of lutein. And it's even better to give lutein alone than with a vitamin mineral supplement. You see, you had better improvements here. So other improvements, lutein with or without antioxidants. You had, well, we'll talk about the other improvements later because it might be a little complicated, and we have a little short time. But you do have other improvements that are really worth having.

Now, about hormone deficiency. Just want to show you one of the hormones that can give, and that is melatonin. These are real pictures. 67-year-old male, retired teacher. His visual acuity had been decreasing. But we see when we look at the retina, you see that this is sort of big bleeding. It was maybe a fibrosis. That's bleeding, and that's fibrosis in the eye. That's very damaging for the eyesight. And you see much less here, much less, much less bleeding, and much less fibrosis. And actually, melatonin was given. I think the dose was three milligrams per day. And, so this must be about like six months later, and the visual acuity had improved or was stabilized. But there was a remarkable improvement. Supplemental hemorrhage. He was getting blind on the left, and on the right is much better. Same picture, same type of picture. A lot of fibrosis and hemorrhages here. And you see what happens when melatonin is given. Eyesight was improved, like sort of repaired. So simple treatment, not expensive, good effects.

Reversing hearing loss and tinnitus. Aldosterone is a hearing hormone. And sensorineural hearing loss is the typical hearing loss that you have when you have this in inner hair cells with aldosterone. So what is sensorineural hearing loss? That will be explained. Sorry, exactly. The sensory cells and then system that is here in the inner ear. And neural means that the nerve, the auditory nerve here, is affected. And basically, you see that with hearing loss, there's, um, it's a hearing loss from when you have low aldosterone levels, where you don't hear the high tones so much anymore. And high frequency tones. Okay. But the low tone sounds, frequency tones, you also hear them less, but not as, as worse. So it's really typical. This is deceiving here. Loss you have when you get older. And that type of hearing loss, presbycusis, call it exactly. Improved with aldosterone, IGF. Well, we'll look, we'll look, of course, in detail in the model here about IGF. The other hearing hormone. Did you know that a local administration of IGF-1 in the ear also reverses sudden hearing loss in humans, hearing loss caused by ischemic current injury in mice, and hearing loss induced by antibiotic guinea pigs? So various types of error, you restore by putting just in the ear drop of IGF-1. And it works well. Talking about a patient having a strong improvement with this treatment. It even decreased the tinnitus at the same time. There are references about IGF-1 treatment reducing hearing loss also in one study was done in humans.

And how to reverse tinnitus? Well, many different ways that can help. To watch out with the air pressure, to not be tired, and things like that. But the diet high in salicylates may help. Aspirin is salicylic acid. And you have acne. The salicylates are actually plant hormones. So you have that in natural foods, but they can also be added as a preservative in food. And you find it often in tomato-based salsas, ketchup, and tea, and wine, and fruits, and fruit juices can contain it. So people with tinnitus may have to watch out for diet high in salicylates. And so we give more information in the model about that. Also, what about oral zinc treatment? I said that increases the chronic tinnitus, but not in these studies. You see studies with patients not having a deficiency. It doesn't seem to work for tinnitus. Also, in other patients, notification is only 7% improved, which is not really remarkable. But I will show a study where it does work when the zinc in patients who have actually low zinc levels. So it works in patients with low zinc levels. Tinnitus hormone deficit supplementation. We see that there's actually, in hyperthyroidism, there's more tinnitus. And the more hypothyroidism, the more severe the hypothyroidism, the more serious there's tinnitus. And you see, for example, in this study here, in 1976, patients who had hypothyroidism and tinnitus, they all reported relief with treatment with thyroid treatment. And this, I can, I can really testify that my patients with tinnitus, when they put on thyroid hormones, two-thirds of them really improve, um, um, substantially with the treatment. So here are references they're showing association between hepatitis and tinnitus. Also, another treatment, oral melatonin. Three milligrams a day of oral melatonin, just one month of treatment. Similarly, greater decrease of tinnitus scores. And especially in men with bilateral tinnitus, they had the greatest improvement on both sides. Not only really help.

What about reverting smell and taste? Well, I will talk about that also about reversing tactile aging. Here we have a little bit short time, but it's really interesting to know the information.

Restoring scalp hair with hormone and nutritional supplementation. There's dry hair under the microscope here. And we'll talk about how to restore dry hair, brittle hair under the microscope. You see this brittleness, huh? It's normal here. This is brittle hair. And uncomfortable here. To give you an example, we'll see about the different deficits between a couple here: biotin, copper deficient, zinc deficient, omega-6 fatty acid deficiency, and thyroid deficiency. Also, let's say the five major types of a combo here. So you have a cause. If you confirm that it's that diagnosis, you know what to do and get the hair come easier.

What about scalp hair loss? In this fifth session of the model on reverse physical aging, we'll look. And I can tell you, this is really important for the patient. If you're able to restore the hair, they really show gratitude for you, and you look like a wonder doctor. But you're not. You're just a very good doctor that actually gives the right treatment to the patient. Because when their hair gets back, they also feel better because the treatment also will improve the whole body. So let's look at one type: diffuse hair loss and thick hair. Diffuse hair loss and thin hair have different causes. Vertex hair loss has also different causes. Hair loss in plaques can have different causes. Frontal-occipital hair loss, the typical male pattern baldness, also has causes. And total hair loss. So basically, these are the principal hormone deficient haircuts. There's really the hormone deficiencies behind it. I'll let you guess what it is. Give you some information on different ones. And diffuse hair loss. Diffuse hair loss can have causes like hypothyroidism, IGF-1 deficiency, nutritional deficiency like iron, zinc, biotin, pantothenic acid, etc. And let's look at thyroid treatment of hypothyroid hair loss. You have before, hepatitis boy, five, six weeks, four months, nine months. So you see a whole change with just thyroid treatment. How potent these hormones are to reverse diffuse hair loss. And this is studies that show relationship between hair loss and hypothyroidism. Here are the studies showing IGF-1 we grow hair. This one of the studies is in humans.

Let's look at another type of hair loss: hair loss in plaques. And this is called alopecia areata. And that can have different causes: cortisol deficiency, hypothyroidism, nutritional deficiencies like vitamin D, etc., yeast infection. And sometimes you need to treat all the causes to really recover the patient's hair. So high dose of prednisone alone decreases alopecia areata. To show that cortisol can help that. It's actually normally the even most potent treatment to do it. But sometimes, if it's yeast infection, you just put a yeast product in the hair, and that's enough. And you see that there was a half of the page that did not improve because the error here was to give prednisone without the other hormones. It's always an error. Most patients have multiple hormone deficiencies. Why not treat it in a balanced way? But it does show that there's efficacy. And here are studies with even more efficacy. And relatively older studies that glucocorticoid supplementation decreases alopecia areata. And here's a topical vitamin D treatment that's given anecdotally to a seven-year-old boy with a two-month history of sudden hair loss on the vertex. And it was topical cortisol, just topically vitamin D. After one month, the improvement. After three months, complete clinical remission.

Male pattern hair loss. Male pattern baldness, thin hair, villus miniaturized hair on both areas, flat hair. The problem with this male pattern baldness is always the same. You get always the same diagnosis like here, your male pattern baldness is partly genetic and partly hereditary, meaning we cannot do anything. Don't even try. And that's not true anymore. We know what is behind that sort of problem. So we can treat it. We did. Did you know that studies show that it's not an excess, but it's a decrease in male hormones? And all male hormones that supports a predisposition to baldness. So too low levels of male hormones give more baldness. There's actually two types of testosterone deficiency in scalp hair loss in men. In male pattern baldness, there's one where the hair has no bald areas. It's, the hair is a little longer, and that patient does not have high dihydrotestosterone. It has average or low dihydrotestosterone. But when there's relatively dihydrotestosterone excess compared to testosterone, there's really an imbalance, strong imbalance. They get bald areas, so the small atrophied hair. So actually, those who have baldness have relatively high dihydrotestosterone and relatively lower than the first type of testosterone. And you see that testosterone, and if you give testosterone, finasteride, that's the treatment. You can get this type of results. 50 milligrams of this maldos testosterone plus finasteride. So it does not work when you give only finasteride. Finasteride alone is dangerous. I will talk about that.

Male pattern baldness is due to testosterone deficiency, relative DHT excess, hyperthyroidism, estrogen deficiency, progesterone deficiency, nutritional deficiency. So we need really to make a good assessment in the patient, right? Good testing to know exactly what is really missing in this person. Because this every male pattern baldness can have different origins.

Female pattern hair loss has estrogen deficiency behind it, or progesterone deficiency, or also like a mental deficiency, and relative DHT excess. Yes, you can have women that lose their hair because they have too low testosterone. That's it's one of the treatments sometimes given to women to get their hair back is testosterone. And there's hypothyroidism, nutritional deficiencies, vitamin B5 and B7. Um, so here are studies showing association of estrogen, female pattern hair loss. So when you have a woman like this, you can make her hair regrow. You see that she's lacking here. It can regrow with estradiol and progesterone. But the thing is that you need to wait four months before you start having improvements. So you need to be patient with hormones. And, um, you will also with the hair growth, thanks to estrogen, progesterone, of course, improvement of other physical signs of estrogen deficiency and progesterone deficiency. That's how you monitor the patient.

Total hair loss. Exactly due to multiple hormone deficiencies. There's always, almost always, an ACTH deficiency, hypothyroidism, the sex hormone deficiency in men and women, and growth hormone deficiency. But the most two important is ACTH deficiency and hypothyroidism. And there's also some nutritional deficiencies like zinc, iron, vitamins B5 and B7, etc. So ACTH and alopecia totalis can give hair growth. And you get that sort of results. So it takes time for getting it. It's not something you have within three weeks. You need a year, a year and a half to get total results. And you need to give all the hormones, different hormones that person is missing. So that will be taught. And what type of hormone for which area of the head to recover, etc., will be seen. Here are references showing that ACTH does decrease alopecia totalis or areata.

And how to reverse gray hair? One of the enigmas is that. But here the enigma is partly unsolved. Although I myself still have some gray hair, so I haven't solved all. But I must say, I didn't apply all the things. Sometimes I always wait. So I have to be a better patient in the next year that comes. And so MSH deficiency and hypothyroidism are the two major hormone deficiencies behind it. And there are nutritional deficiencies. We'll talk more or less abundantly about it. We already gave some information in the beginning of this lecture for the nutrient deficiency. And this is the story, one of the two anecdotal cases I will talk about, a person having gray hair and totally reversing with getting thyroid therapy. So give the details more in the lecture on the session on scalp hair loss.

Now, another is how to restore the aging of the face, huh, with hormone and nutritional supplements. Can we do that? Yes, we can. With other procedures than this aesthetical medicine. For this, much of the aging here that people get is unnecessary. And you are the magician. You're there in your seat there, or you are the person who's able, as a health professional, as a doctor, as a physician, to reverse the situation. So much of the information of here is in with a lot of pictures, a lot of practical information, and many scientific references. And you get, for example, what is important to know is that the face wrinkles as the belly bloats. So the more bloating the belly is, and the more droopy it is, the more wrinkles they are. And it's not just pores, it's almost always like that. So basically, to improve, you also must improve the intestines, good food, etc., the right food, right time of the food. And we'll talk about what is the right time of food will be. So this is also explained in the book. And all the treatments, you see that in this reverse physical aging, you see in yellow are the more important treatments. In light yellow are the treatments that may work, but not as good as the ones who are marked in bright yellow. And then those in white will work, but not dramatically compared to the treatments that have a bright yellow background. So you immediately know what may help best for, in this example, wrinkles and things like that. So it's a book really that is probably ahead of its time, but it's part of this time because the information is already there, and it's just brought together.

So in facial aging, we'll see aging faces, facial color abnormalities, swollen faces, thin faces, wrinkles. And we'll see different topics of that. For aging faces, will be, uh, also less masculine faces, less feminine faces, dehydrated faces, sun damage face. All types of aging of the face will be overlooked. Another will look also about when the face, the tint of the color is too pale of the face, or it gets yellowish, or pigment spots, or melasma. How to reverse that? Because it's reversible by treating the cause. Puffy the face, it's too swollen. Puffy faces, obese faces, moonlight swollen face, different type of swelling of the face. And also different types of having a thin face, a hollow face, a hollow face, or a very thin face, or faced without enough muscles, it's losing its muscles, or wrinkles. So basically, we'll have a really, you will get the information that you need to help patients recover a better appearance of their face again.

Reversing the aging phases. For example, this is growth hormone with a lot of typical signs: with the sagging eyelids, the sagging cheeks here, the flat volume of the hair, and the volume of the hair is much better here. And there's less forehead wrinkles. There were some, there were none here. There's no nasolabial folds anymore, and there's firmer cheeks. And this patient felt much better. Really, that was even the greatest debate. I published a study in 1997. I was the first patient I treated with growth hormone treatment. And we saw that 71% had a less wrinkled face with growth hormone treatment, and did not have a less wrinkled face. So most patients really had less, but they had less eyelid ptosis, the droopy eyelids were less, the sagging cheeks were less here, and the skin folds, the folds on the skin were less in many of these patients. She really had an improvement.

Also, in this lecture, we'll give information on tips on growth hormone. And one of the information is here that IGF-1 can increase free T3. Growth hormone can increase it even more. But when you give growth hormone and IGF-1, it markedly increases the thyroid hormone. So that patients who take thyroid hormones may have to decrease by 30 to 50% their treatment.

Topical melatonin for the face is one of the treatments. If there exists a topical, really good, good cream, oil, you can put on the face. I received some samples, and basically, I almost never succeeded in being able to put it because my wife and my two daughters, they take it directly away and keep it for themselves. So basically, I have to insist more to get my own sample, and I think I have to hide it away because that's the only way that I will be able to use it because they're so happy about it. And I know many patients are really happy about it because it gives a rejuvenating effect that is very good.

Now, how to reverse the face that loses its masculinity? Masculine, less masculine, or less feminine depending on the sex. Well, there's something very special that we'll talk about is that men are getting less male, maybe a little less sexy. Actually, because when you look at the skulls of our ancestors, 50,000, 100,000 years ago, that's how they looked. But look at now, it's, it's smaller, and it's, it's less masculine. Actually, the eyebrows, for example, there were more bones there, they were more masculine. But they were probably also more violent. And that's difficult to live in society. So exactly, we're having now are the men are having a sort of impaired production or less decreasing sensitivity of testosterone. And see this, to show, um, um, the, what the stars doesn't matter. You see that this man has a relatively short face. Okay, that is a mark that is adulthood testosterone. Since he passed the puberty, that was too low. He also doesn't have much beard. Okay. Look at this man. This man probably has a strong beard. And, but basically, he has a longer face, and that is linked to more adulthood testosterone. There are other characters of the face, the link to testosterone that we'll see in the model. Here's one other eyebrows. You see small and are almost non-existing eyebrows. Low adult testosterone in saliva. And when it's pronounced in the middle here, near the nose, that part that is dominated by testosterone. And if it's, there's a lot, it means there's high adult testosterone since long.

How to reverse the declining sexuality of the aging faces? Well, the feminine face. This is a very masculine face. This is a masculine, it's more angular. While when the face gets more feminine, it is actually more oval, oval. You see it gets more roundish. And estrogen can also decrease skin wrinkling and dry skin. Post-menopausal woman, you see less wrinkled skin, less, and now dry skin with, uh, less than about 33% less, one-third less wrinkles. So it has efficacy. And we'll see other studies and other information for you to know to do to be a good doctor.

Reversing dehydrated face, face that has not enough water inside of it. And you see when you have the eyes that are deep in the orbits, and there are sharp wrinkles here, and little folds here. Well, that can be several deficiencies. Can be vasopressin or aldosterone deficiency, especially around the corner of the eyes. The crow's feet wrinkles are improved by taking fludrocortisone. Aldosterone, fludrocortisone is the synthetic form of aldosterone. But also desmopressin can improve that. It depends what the deficiency is. And we'll try to help you to be able to discriminate between what is deficient. You see this is studies on skin folds as a sign of dehydration, the association with vasopressin deficiency.

So how to restore when the face has been damaged by the sun? Well, one of these treatments is again melatonin. It can improve the proliferation of keratinocytes. You see here, for example, you see an improvement of the keratinocytes in vitro. And melatonin not only improves the keratinocytes, the epidermis here, but can also improve the skin fibroblast survival, so that they can make collagen, so that skin gets better, younger. You see that when skin is exposed to ultraviolet B, you actually have a decrease of about 50%, almost 50% of the fibroblasts die. Well, this almost nothing dies, none dies with melatonin treatment in the culture. So it really helps to protect the skin.

And so, how to influence the skin tint of the face? Well, first, how to improve a pale face? This is typical pale face of estrogen deficiency. But there are other deficiencies that give pale face, like thyroid and others. And then testosterone deficiency. Well, you basically need to give the hormones that are missing to improve the situation. How to improve the sun tanning of the face? That the face can sometimes easier. Before and after, you see that it really gives a darker skin. Um, so we'll talk about different things how to do it. Um, and also what is more problematic for many patients is when they have pigment spots and it doesn't go away, or melasma. So this is a person with hyperpigmentation spots, and she receives a topical melatonin, vitamin C supplementation. After two years, it's better. It's even better if you would treat another cause, but I will talk about that in the session.

How to slim swollen faces? This is a swollen face. There's hypothyroidism that can swell up. Too low thyroid, also too much estrogens can give that by fluid retention, or cortisol excess can give that. Also our insulin excess, but then there's too much fat in the face. So there's really ways to discriminate what the cause is behind the swelling of the face. So you know how to give the good treatment. Of course, you still need to do a laboratory test and do it. Well, growth hormone nitrogen excess can also give a swollen face. And it will tell you how to discriminate. And then eventually also aldosterone or excess can give a swollen face. Now, this is a puffy face, swollen more in the morning because of the low thyroid. And when you get there, we'll see the change. So we'll try to get you enough before and after pictures of every cause of swelling of the face, so that you really can recognize that it gets into a sixth sense, like an intuition that you get. And you see here, woman with adequate estrogen and progesterone balanced, they look slim in face. Average, especially this woman. Well-balanced. This when she gets, when a woman gets in estrogen predominance, she gets bigger breasts and swells more in the face. And then when it's even much more, much bigger breasts, much more swelling in the face, severe estrogen predominance. So we'll tell how to correct that so that you are able to do it well. So at certain time, you will also be able to recognize what the degree of severity is of the excess or the deficiency of hormone that causes the swelling of the face.

How to get smaller faces become bigger? Is it possible? Yes, yes, it is. So there's several types of hollow face. There's also thin face or sarcopenic face with lack of muscles. And hollow face, it's the facial cortisol deficient or estrogen deficiency, aldosterone deficiency. Can also be caused very thin face. You really have to think on insulin deficiency or cortisol deficiency. And sarcopenic face are face lacking muscles, growth monitoring deficiency, but also testosterone deficiency may be behind that. So as you see, I try always to give you an overview so that you are able to get an idea of what is causing a certain change of appearance of our body. And so what to give as a treatment after lab test confirmation of the deficiency or excess. So this is untreated patient that is lacking cortisol. You see also he has pigmentation part. His face is more pigmented. And look to change with hydrocortisone treatment. Two years out, he also looks more muscular because other glands work better if the adrenal deficiency is corrected. And he has also more light color Caucasian skin, while he it was brownish with dark circles under the eyes. So thin face association with cortisol deficiency and insulin deficiency. And thin face and etc. Also, getting a too little less muscular face due to excess thyroid hormones. So we'll see many of those. See different situations. And then these are the references.

Now, how do you reduce wrinkles by treating causes, not by putting fillers? Also, all sorts of inflammatory things you can improve. You can use aesthetical medicine in second position, but first, you need to treat the cause. But the cause cannot be improved if it cannot be improved. Because most of it really can be improved, then you do aesthetical procedures. So we'll look about what can do for forehead wrinkles, each set for frown lines, crow's feet wrinkles, nasolabial folds, upper chin wrinkles, and, um, here, for example, you see that growth hormone deficient pre-pubertal children have actually a higher stiffness score in yellow here, and lack of skin elasticity. The non-elasticity index is higher. So they already have an aging skin. Again, references about that that show that. So we'll go over and we'll end this session on the face. Then restoring the face by hormone mesotherapy for wrinkles. And we'll talk also about the details and the doses that need to be given.

Restoring the neck, chest, back, and arms with hormone and nutritional supplementation. So how can you improve the neck result? The face, the head, actually, with the hair. Now let's do the neck and upper body, actually. Well, there are several ways. There's reversing the aging of the upper body. We'll see, as you see, the neck, the chest, the back, the arms, and hands. And we'll see different aspects there that we'll see one after the other. So you see, uh, loose skin folds on the neck, reuter, for example, organomegaly, pseudogynecomastia on the chest, are small or large breasts, droopy breasts, body hair overgrowth, the fatty back, the circumventing back. There's so many, many different things. The small and the large shoulders, thick arms, thin arms, sagging triceps, dry skin on the arms, pigmented arms, aging hands, atrophic hands, small hands, swollen hands, rheumatoid hands, lunulae, the nails, different nails, brittle nails, and different things. And so all these aspects that often happen with aging have a cause, are causes, and are partly or totally reversible with the hormone or nutritional treatment.

Let's look at the chest first. We passed the neck. This is how a chest should look like of a healthy woman. And this is how a chest should look like of a healthy man. Firm. Firm is the word. Firm, good structured, well-structured. That means sufficient hormones. Firm, firm chest. And this is obese chest. Something's wrong here. In Klinefelter syndrome, they have a lack of testosterone, poorly muscled, and obese chest. And adult-onset testosterone deficiency has that also. So it's a feminization of the chest. Competitor, we just saw of the very male masculine chest that we shot just before. And, and so let's look at gynecomastia. Gynecomastia is with milk glands, exactly with too much estrogens in the blood. And that is the same from women as for men. You see men have acne as women breasts when they have too much. In women, it's called macromastia when the breasts are very big. And men, gynecomastia. So testosterone deficiency can create gynecomastia. There's many references on that. But basically, there's also generally also high levels at the same time of estrogens, especially of estradiol in the serum. We'll talk about also the usefulness or the limits also of anabolic steroids in in the case to improve the chest. And then we'll look at enlarged breast in women. And for example, a large breast can also persist. And it's then generally a sign that there's estrogen excess, that's estrogen predominance. And so usually behind the estrogen excess is actually a progesterone deficiency that permits estrogen excess. So progesterone normally will decrease deficiency of estrogens by converting the very potent estradiol to the lowly, very the weak estrogen. Strong. So that's what the best benefit is. None of progesterone. The estradiol, very potent, piles up, and there's estrogen dominance. Testosterone can also be deficient because testosterone is necessary to oppose estrogens. It's usually when men, women receive high dose of testosterone, and makes them breast flat. The breasts shrink in certain sense. It works like a progesterone. Alcohol, coffee, tea, and other caffeinated drinks and food can give also high estradiol levels. We'll talk about that in the session. And also endocrine disruptors. Endocrine disruptors are substances out of toxins actually of the environment, like pesticides, that have an estrogenic activity and then can also enlarge the breast of a woman. Iodine deficiency, vitamin B6 deficiency, and vitamin A also may give problems. And also thyroid and cortisol deficiency, because in those deficiencies, there's no good ovulation, and then there's not enough progesterone made in the second half of the cycle. So you can improve ovulation and progesterone production by giving thyroid and cortisol. So we'll give also doses of the treatment in the session how to do it.

Armpits can be too brownish armpits. That's cortisol deficiency. And we'll talk about how to get rid of it without aesthetical pressure. You just need to correct the deficiency behind that. Thick arms. You see the thick arms that can be just swollen because it's full of myxedema and not even fat. That can be due to thyroid deficiency, as in those two patients. And sagging triceps is basically with growth hormone therapy. You decrease the droopy triceps. You see it gets firmer triceps after where's growth hormone supplementation. There's one hormone that does it even much more. We'll talk about that. I'll keep that as a surprise for you because it's really important to know.

Aging hands. Aging hands like this. If there's a lack of tone, you just push here on your own hand. If it's a lack of tone, you're lacking growth hormone. Because if you take growth hormone, you have an improvement of this tonus. 42% of the patients will improve. That's a study that I published when I, in 1997.

Swollen hands. Biliary deficiency. Typically, if it's swollen and it's not really fluid retention, it's just tonic, and it's more swollen in the morning. You have to suspect thyroid deficiency, hypothyroidism. And here are some of the studies showing a relationship. Also, study I published in 2004.

So then we're at the last part of our model on reversing physical aging. How to restore the aging of the lower body? And again, we'll see several parts. We'll see the abdomen. It's very important to have a beautiful abdomen. And I say this to men, it's much more important than women, because women genetically are programmed to first look at a man on the belly. The belly is flat, they are more attracted. Good to know. Abdomen, pelvis, male genitals, female genitals, legs, and feet. Well, all looked in that session about the things. So we'll see obese abdomen or droopy abdomen, pubic hair, inguinal folds, hernia, anus, buttocks, droopy buttocks, for example, the penis, loose foreskin, phimosis, or small penis, Peyronie's disease. What to do? Because it's reversible. Testicles, small testicles, varicocele, lax scrotum, prostate hypertrophy and cancer, clitoral atrophy, vulvar atrophy in women, vaginal prolapse. Must say for hyperactive probiotics, it's better to do prevention by giving the hormones. Sometimes, once you have that, much more difficult to restore. You can have good efficacy, but not fantastic. If it's very, very important in the very beginning stage, you're efficient with the treatments. Atrophic legs, sagging in the sides of the thighs, cellulite, really efficient treatment for the light fatty knees, thick calves, swollen calves, thin skin on lower legs, bruises on legs, varicose veins, venous leg ulcers, swollen feet. They say tripod therapy. Well, so we'll see many, many different. We even look at gangrene of the feet and toes, actually, with hormones can be reversed if you're on time.

So obese abdomen supplementation works on the flat abdomen. And this is what happens with growth hormone supplementation. It's a picture I downloaded from the internet, but it's basically what happens. You have a decrease in fat in the abdomen, and it gets firmer muscles. And here's a CT scan before and after growth hormone treatment. You see that after growth hormone treatment, there's a sort of disappearance of the fat. The fat, the black here around is fat tissue. It's much less, almost disappeared in the frontal part, and 50% less in the back. But also in the middle, there's a lot of fat in the visceral fat, and that's also decreased. And the retroperitoneal fat that is here, that is also much less. So that's growth hormone. Of course, it's not the lowest dose of growth hormone. It's a good dose. There was a dose, I think of two units a day, that was given to these patients. Again, in kilos, you see that after half a year of growth hormone treatment, there was about almost two kilos of lean mass extra, but there was six kilos of fat mass less, to show how efficient it is to give growth hormone.

What about the buttocks? Well, you have buttocks that can be insulin excess and insulin deficiency. You cannot reverse this droopiness of the buttocks without adding insulin into the treatment. Even with growth hormone and IGF-1 and testosterone, etc., you cannot reverse it sufficiently. You need also insulin in these patients. And you can only give insulin if they're normal weight or low weight, not if they're high weight. So we'll talk about all these differences and how to do it safely and efficiently. You have other causes of fatty buttocks: estrogenic cells, thyroid deficiency, other causes of droopiness. But IGF-1, growth hormone, testosterone deficiencies for in both, actually. So often, it's a combination of treatment needed to reverse the droopiness of the buttocks or the fatty buttocks.

Penis. The penis can shrink with aging or may have never been long enough. So these are the pubertal stages of Tanner stages of male genital development. And you see that if an adult above 22 years has this type of penis, this size, he hasn't had an adult level of androgens. But if he had a smaller size like this, he had probably had always too low androgen levels to completely develop his penis size. So with that information, we know that this patient probably needs testosterone. It's not just a characteristic because the lower testosterone levels are low are linked to less life expectancy, to more diabetes, to more obesity, and to more fatigue, for example. So, so, so it's just not benign. And it does give an idea of the testosterone impregnation since many years of the patient. The penis size. Topical testosterone on the penis of boys with very small penis, hypospadias, actually 1% testosterone problem, which is not much. After one month, increase of penile diameter, length, and glans diameter was also increased. And there were side effects. There was some pubic hair developing and darkening the skin. But when you stopped the treatment after three months, everything was gone again. There was no pubic hair anymore. And that's it. Well, fell away.

What about Peyronie's disease? This is Peyronie's disease, an inflammatory condition with some hardness here, curved, painful erections, also because of a sort of fibrosis here. It's reversible. We'll talk about the treatment in the model.

Small testicles. The smaller the testicle, the less spermatogenesis there is. That's why it's always interesting that you could check in your patient the size of the penis, the size of the testicles, because that gives a good idea of your spermatozoids, the number of spermatogenesis. If it's small, there's not much spermatogenesis.

Lax scrotum. Depending on the scrotum here, this is tone scrotum. I would say it's good. But this is an animal-sized testicles with two lax scrotum. And then it's even much more an older adult that.

indicates that there's the sashing deficiency much more than the hydro testosterone because testosterone is a muscle hormone and here it's a lack of muscles here also lack of growth hormone can get that but basically mostly lack of testosterone so when you have that in your patient you know testosterone is probably too low.

Prostate hypertrophy you see that zinc can decrease prostate volume and also can decrease infect in inflammation so also urination is done better so zinc is really a treatment that can help very well and we'll talk about other treatments that are even more potent with hormones in the the session.

What about reversing female genitals? Well, we'll talk about that in many details about clitoris size and and and prolapse things like that. I'll keep you a little bit um waiting because um other things we're going to see now.

Leg atrophy the mechanism is the lack of anabolic hormones but it also can be a lack of physical exercise and amino acid supply so you might have to work on giving the hormones that are missing but also increasing the amino acid supply and making the patient have physical exercise.

Sag inner tire size of the thighs you see in this study that i published was that growth hormone decreased in 50 percent of the patients the sagging inner sides of the ties meaning that the ties got firmer and half the patient who are taking grotomo.

Cellulite this is cellulite uh well think about testosterone this is our female to male transsexuals you know she she became a he and uh after 12 months of testosterone in the study actually um showed that the testosterone markedly increased the time muscle area and decreased all subcutaneous fat they pose so you had more muscles less fat in the ties that's decreasing cellulite so you see that subcutaneous thai fat was decreased and the hip and abdominal fat was decreased too but not the visual fat that had a little bit an increase.

Swollen calves with spitting edema aldosterone excess is frequent cause of uh swollen calcium spitting edema so because aldosterone keeps on fluid and so you keep on the fluid in the leg and uh gives this sort of aldosterone excess transiently swollen calves you see you get a pitting edema.

Thyroid deficiencies you can also give swan calms but you don't get pitting edema so and it's mostly in the evening and the hot the second half of the day that you get the swelling not in the morning.

Bruises on legs many causes testosterone deficiencies the main hormone cause behind that and uh there can be also due to hypothyroidism because there's a lack of coagulation factors there are many different nutritional deficiencies that can give them.

Varicose veins on the legs there's an association with low testosterone levels venous leg ulcers can be improved by testosterone it's really a repair hormone you see here after three this after two months after three months after eight months and this is almost you're going to lose the leg here you saved it so we'll talk talk about the doses that are applied and and so that worked.

Now we finished uh here this lecture i'm going to give you some information and then we'll have questions and answers so you can type on your questions um so we'll answer but first let me talk to you about that we need to make the movement grow my idea is to to help as much physician as possible so we need so if you know doctors that can be interested local companies uh scientific societies that we can contact give us the details give us the number pharmacist that may be interested of working pharmacists that can send products to where interesting to know that so if you know share this information with isabel isabel is reachable on this email isabel at sign her talk dot eu so please you will really help you grow also with this movement.

Then i want to talk to you about the evidence-based hormone therapy training program because this is part of the evidence-based hormone therapy program.

You can first of all try to join this postgraduate program uh you find a lot of practical information for your practice that you can share uh you can contact officeearth.edu for that or the previous of isabella is also reachable and this postgraduate program there's three two different three different options there's an option that you go to full year and you have a special covet price now that normally ends end of december so you will pay less if you subscribe now there is also a second um possibility is just subscribe for one model you can just subscribe for this model of eight sessions for example if that is in your interest and or you can or another one that might be more interesting like the fatigue and burnout syndrome session so you have a lot of different options and then you have a special nutritional program so this is the option where you just would go into what i just showed the reversing physical aging course and that just this session you can can um subscribe for you can also subscribe if you're just interested in nutritional parts the first topic the first topic of each model has a lot of nutritional information dietary nutrition from that really practice you can just also go into that program special price that is much less if you are interested in.

And then there are books that are important and if you really want to do harmony you need to buy this book this is the hormone handbook because it really has all the different information you need to know uh it's very interesting this half of the book is also scientific references but basically it's very very very easy uh reading um and and you know exactly what you need to know for treatment you don't have time you just look at everything has yellow background bright yellow background that is more important you'll already know a lot.

Then there's the testosterone the therapy for a real gentleman that i think is the most extensive book was the most extensive reference but also the most practical information on testosterone therapy it has information also on how to reverse prostate hypertrophy how to disperse gynecomastia and how to to get down down but not too much down the the high estrogen levels and what they may cause as a problem and everything you ever turns around testosterone is in this book.

There's also a reversing physical aging book that is the book that really has a lot of material that you have in the model on reversing physical aging so a lot eleven hundred eleven hundred pages really interesting and then the atlas of the endocrinology formula they're also very interesting has been recently updated also with references but there's more than 650 pictures of of hormone therapy 20 hormone deficiencies and 19 hormone excesses so really really the information you need if you start with two books it's the hormone handbook and atlas you need to start and then the other books come in second position for you as a help so you can buy them on hertogmedicalschool.eu.

And then there are some general public book there's one on oxytocin the general here the hormone handbook for patients that is a reduced form of the hormone handbook we also are very happy because we to have partners people that help us uh grow the movement and um i think i'm going to let talk uh here i have to click on it yes hi everyone i am joe from farming belgium first of all i want to thank terry and claude and their team for the tremendous work they're doing with their movement towards more prevention and better help for all former north is one of europe's largest producers of very high quality food supplements and is active in 45 countries with more than 400 studies were conducted with the final products of farming arts lots of universities use our products because of the unique level of bioavailability besides our ketone the bioactive q10 and the selenium present in our melatonin the supplement will form bio-melatonin complex and a melatonin three milligram former north is a registration truck in belgium these are deep pearls probably the best known products i think that everyone today is convinced that the benefits of vitamin d in great britain our deep pearls is used at this moment by 5 000 british people in a large vitamin d study in the battle against kovitz 19. those things make us very proud if in the meanwhile we could mean something for you or your patients or if you you could use a sample or form another product you can always cover this gerry thank you very much for this time and everyone have a really nice day bye.

So there was your class of farming which is really high quality company we always like to work with them because they have the good products and here i have um noah from the philippines hello everyone my name is noah i'm the founder of and consultant compounding pharmacist at sweet sweet pharmacy co-founding lab and as a fan of bhrt that came through my successful encounters with different patients in the last 80 years it's important to highlight that the teaching of dr hairtop had a great impact and a great difference in in patients lives with especially those with dysfunctions and hormonal imbalances and that's why i was so keen to join dr herton medical school and get enrolled in his evidence-based hormonal therapy online training and to gain more knowledge about the bhrt and actually from the very first module i learned a lot and i'm sure that this training will will have a great impact on you in your practice as well so i encourage you to join the the evidence-based hormonal therapy training and let's join hands and make big difference in our patients lives thanks to dr herton thank you noah thank you.

And here is nicholas hello everyone it's a pleasure for me to introduce you laboratory laboratory has been created in 1993 in france positioning themselves on the natural health project market since their beginnings our main focus has always been to offer the best natural health products laboratory cockpit provide monthly synergized formula for maximum efficiency our full commitment.

Percent biodegradable and recyclable pips box our pillbox are made of sugarcane guaranteed oil-free which is good for people and good for the planet and number four quality controls our products are made in france under quality insurance from iso 22 000 certified laboratories thank you for listening thank you nicolas.

So nicholas is nicholas is really um um they have really a firm that is doing the sustainable and saving the planet and good product so you have all the advantages here are a lot of other uh contributors that help us to grow the movement it's too much to tell but it's 90 degrees there's access they're pharmanor there's uh qualified there's uh ivan a mercury preventage energy it and a transvital plus um portals hepatic and and an anti-aging system very important uh in the movement uh and so so basically we're bionuri so so we are very happy to work with all these these partners.

Now also before i'm going to question answer and after that short because we're extending there's a next live free webinar so really book the date will be february the 2nd 2021 it's normally at the same time and it will go on female hormone deficient therapy you will see it goes further than we have it will be shorter uh this is that exten this is the longest i think we we have as a free webinar due to the fact that it's over an extensive uh reversing physical aging book and so we'll we'll have some questions and answers.

Um i will see if there's the the question and answer here i have 40 questions won't be able to see all the questions but will will some of the questions might be uh taken over in our question and answer session i must say that those who go in the models they we have um every month uh uh question and answer session where you can ask the question and i can tell you they were all very excited about it because also the questions are very interesting and not only the answers.

So i will go now on the questions and i have questions here how about a cheesy snack uh stated uh how about the cheese i think a cheesy snack is with cheese and it's certainly very bad for uh wrinkles and for um um because the it's it's it was a milk product that irritates intestines cow milk is not made for us if you take it once a month it's not a problem a cheesy snack but if you take it regularly it's a problem.

If cortisol then the question is from angie uttami if cortisol is around six can we use growth among i don't know what the six is i suppose it's low i think it's if the cortisol is too low you're in danger by giving growth more because growth one decreases the cortisol so you need to correct that or to give very small dose of cortisol because the person won't tolerate an optimal dose.

What nutrient can upgrade the acth level i don't know what neutron can upgrade the shl i know what cortisol eventually can be improved it can be improved with vitamin c for example and amino acids but i don't know for sath.

How dhe works in kovit 19 well you should go in the model in the model on infection where we have all the details for this but i must say that i didn't find a study where dhea was active in cov19 but it should be because dhea is very active to many different viruses and including the hiv virus where it seems to slow it down.

How paranoid work for anti-aging a parathyroid hormone can reverse osteoporosis 12 in a year if you really do a good treatment so it can help to enantiation but if you give too much paratoid it's also not good but it's so expensive that basically you won't give too much that's over.

You nicole perez uh best is this kid or synthetic diet best is desiccated thyroid i would give because it has a more 24 hour on 24 hour effect per more permanent effect.

Is fsh normal less than 7 four fifty year old lady if it's less than seven uh for a 50 year old lady she's probably not menopausal because the fsh is above 30 or at 30 when there's menopause so it looks that she still has menstruation and is still low or this woman has if she's menopausal she has a difficulty of secreting tsh something's wrong there but then that demands for the investigation.

Then generally fisher says do we have research showing that testosterone or growth hormone supplementation will decrease at their schools even in the absence of deficiency um well the research is actually not based on deficiencies the research showed that when you give gr test growth more testosterone is less efficient but growth hormone it there i think there are eight studies showing that they decrease at your host whether you have a deficiency or not it's just given in all the men who have uh atherosclerosis they don't really look at the deficiency and just give growth more to see if it works on that earth coast and that it does show good efficacy.

Then um what reference range do you aim for replacement of estradiol possessing a testosterone woman i would say let's go and look at the model that will be over that because you'll have very specific information because the references are usually those of young adults but depending on the type of person it may defer.

Will this affect will this affect ones who have cancer so the patients who have cancer first have to treat their cancer by removing the tumor if it's possible and then they can take the treatment uh many studies showed that in female breast cancer and in prostate cancer men you can give hormones it doesn't increase the recurrence.

If we have diabetic patient with almost blind eyes can we reverse with hormone and nutrition what hormone and nutrition um well if it's diabetic patients often there's so much damage done to the eye that you cannot totally reverse it probably with hormones and nutrition if you're on the late stage but if in early stage you probably can totally reverse it now which nutrients it depends on the deficiency the person has if you go and look at my textbook of reversing physically you get all the details of what nutrients are important to reverse the eyesight depending on what the problem is and then you know what to search for in the lab test and what to give then as a treatment.

Can we use l-carnitine in 14 year olds with slow muscle mass you can give al carnitine to 14 years old with low musculus not of danger the only thing that you need to be in in um taking into account if you get very high amounts of um carnitine it does decrease the thyroid function it decreases the conversion of t4 to t3 so you're getting sort of hypothyroidism.

How old your younger patient treat with insulin i suppose that the question is what was your youngest patient treated with insulin without having real diabetes for i i usually only treat very old people are very thin people but but that are still already above age 30 with insulin a small dose of insulin to improve their looks when they already are starting to age.

Can give estrogen therapy to estrogen and breast cancer yes you can and i will extensively and i hope i will have an expert in the model on female hormone therapy that will talk about that you can but there are some conditions that you need to respect uh and small doses and um a certain time after the cancer.

How to test are is there any lab to detect relax relaxing deficiency no there's no lab test to detect relaxing deficiency i'll go over because i get about the same person's asking the questions.

How much does those how much dose in melatonin topical i think it's a 0.05 percent that uh is is very helpful of melatonin but there are different doses depending on what the problem may be but there's a good lotion that i use i think it's 05 that's that's good but the the thing is that um it has to be well prepared by a very good firm otherwise it has a bad smell and uh so so try to find a good product.

How much dose in uh can we treat kilowatt or hepatropic scarcity monotony i don't think it's very efficient to treat scars with or hepatitis cardiac melatonin there are other treatments including cortisol.

Here i have alice riggery if after a normal liposuction the skin is left with way more or less fibroblasts than before it could be done is there a way to regenerate fibroblasts with injections yes and while we're talking about in the session on reverse physical aging about doing mesotherapy locally it has very very good effects on reversing and improving the skin when it has been too loose after liposuction.

What are doses for growth managerial mixtures for vasopressin for lexing all the doses will be given in in the the lecture but it depends on the patients so it's not just one dose for everybody that's why you really need to to start studying and idealist not only taking the reverse the model on reverse physical aging but also to to go in the model on that hormone their treatment because you get so many details that you really get much more expert in the field.

The dosage of ts-65 not sure i thought it was of five units but i'm not sure about the doses of ts65 which is a telomerase activator.

Can get a handout of your wonderful presentation uh normally those who subscribe to the model have have a handout of this i i don't know if they get it i'm not one in that minister fighter i will ask the question on those who who do it please again.

How can you calculate according to igf niger um we'll have a little a whole model on growth more well well be explained because it and for growth maybe even it's very important to know the size of the person bigger toss more different but there's a special ratio there's a bioavailable ratio and the references for example between 20 and 85 and it's around the 35 45 45 accurate that you need to be of a ratio.

In minimal stuff here i have so i see this patient coming from in a doctor from indonesia i have a nine-year-old daughter with macular degeneration caused by torch when she was baby her visual was poor can she be treated by melatonin at her age a daughter of a nine year can certainly be treated with melatonin i i think it's even you can try uh to um take um an oral form eventually to give high amount and probably uh to make some drops eye drops maybe just mix a sort of fluid for physiological serum in the eye and then put maybe um some melatonin in it but i think there's a deeper treatment that is possible to do and it might be for example if i had such a bit i would do mesotherapy injections around the eyes and that probably would be a a solution now this this child has 110 pounds that's about 50 kilos it's a bit much at nine years so there's another problem hypothyroidism probably and other.

Okay i'll do one more question uh just one more question there's many questions about growth hormone cause cancer estrogen causing cancer i can tell you there's ways to avoid cancer and growth normally decreases the cancer incidence by 50 in patients with severe deficiency so it's okay but you need to really have a more in-depth lecture than just a quick the the answer is not just simple that in all cases you don't have cancer in generally it's very safe treatments but if you estrogen is too much pressure's not enough you may be promoting cancer if there's breast pain for example so you need to have a good ratio there's a myoma is not a contraindication normally for growth amount but it's contraindication to give too much estrogens.

And then um where to get the fluid melatonin there's a brand called radiance radiance r a d i a n c radiance like radiation and that is done by the group nelly diverse they're in canada but i think they can ship all over and it's really the best form of melatonin i think that we have on the local uh treatment it even decreased skin cancer and things like that so it doesn't only have anti-aging effect.

Okay um i think we'll we'll stop here um i must say that we have question and answer sessions within the sessions that are very interesting uh i think it's because the the questions are awesome also life you you you can be the one who's talking actually replacing me for a moment so you ask your questions so we there's much more interactive so i think really being part of the program will really help you to to to know more because uh here we're having maybe 15 minutes of question answer imagine when we have a whole hour and i can say after an hour i'm more tired than those two hours that i just did now but i'm i'm also fascinated because the questions are really really interesting so i thank you for attention thank you for being there and i hope i will see you on the second february and i hope i will see you maybe also on our models uh really uh that are interesting see you then bye-bye.