So many people are suffering from brain fog, weight gain, water retention, poor response to exercise, poor sleep, poor deep sleep, and they think that these are just consequences of aging. They’re not. They’re consequences of missing raw material. It is astounding what happens to human beings when you just give their body the raw material it needs to do its job.

You know, in plant physiology we believe this, right? If anyone had a leaf rotting in a palm tree or a tree in their yard and a true arborist came to their house, they wouldn’t even touch the…

Gary Breau is a human biologist. To say that this guy has changed my life is the understatement of the century. I will add 7 years to the lifespan and the health span of every person in this room. Of all the biohacks, I’m probably most excited about hydrogen gas and hydrogen water. Do you have an impact? Do you feel different? No question. I think it’s the most overlooked in all of biohacking today. We know that we can’t change the pH of the body by drinking alkaline water. We can change the pH of the body by adding hydrogen gas. This is what I call the Golden Age of Healthspan. Why some people live to 120 and others are dead at 50? There’s a reason, and we’re going to be able to understand that and begin to impact that now. That’s a moonshot, ladies and gentlemen.

Everybody, welcome to Moonshots! My guest today is Gary Breau, renowned human biologist, biohacker, and longevity expert with over 20 years of experience on optimizing human performance and functional medicine. Gary and I are going to be talking about the technology that’s available to you today, in your home, in your life, to help you extend your health span and your lifespan. He’s the co-founder of 10x Health Systems, past CEO of Streamlined Medical Group, and the host of The Ultimate Human podcast. I recently visited him in Miami, got a chance to play with his toys. He is the kid with the most biology and ultimate hacking toys out there. We’ll be going through it: what you can use today, uh, what he does and when he does it. Uh, you’re going to want to take some notes here and decide what you want on your Christmas list. All right, but let’s jump into our podcast on the technology you can use for optimizing your health and performance. Gary, welcome to Moonshots, buddy.

I’m so excited to be here, man. I really am.

Yeah, you know, it’s like I enjoyed being at your home in Miami. Uh, it was a technology showcase for sure. You know, and and we’re going to talk about uh a range of technologies that people need to understand are becoming available today that can help you first off understand what’s going on inside your body and then how to improve it. Uh, and these are not technologies that are super expensive. They’re not technologies that take a huge amount of time, uh, but they are hacks and tricks and so forth, and I think we’re going to start to see, especially as AI starts to play into this, I agree, this coming decade. You know, I’m imagining that when I come back to Gary Breau’s home uh in the next few years, I’m going to be… you’re going to be sitting there talking to Jarvis, and Jarvis… Jarvis is going to be picking up all of your, you know, all of your sensors on your body and saying, “Gary, hop in the hydren bath. I need some cryo. I need this.” It’s going to be… I mean, you can turn on your AI biohacker support system.

Right. Right, right. Yeah, I believe in that too. You know, I think everybody’s excited about my biohacking habit except my wife, ‘cause I… every single room in the house has got something in it. You know, um… I mean, I guess there are other things, better things you could… or worse things you could be addicted to. I… I don’t collect cars or anything like that. I mean, she was in the jacuzzi… right, right there anyway at the time.

Yeah, she was in the cold plunge. She… in the cold plunge. That’s right. Yeah, yeah. And um… uh, but I think when I finally put the H cat machine… when I put the transdermal ozone machine in our master bedroom, she was like, “Okay, I’ve had enough of your… bing that…”

But it’s amazing, you know. I mean, it’s… I’m just… I have a childlike fascination with human performance and and cellular biology and and all of the technology… this bridge between artificial um intelligence technology and and human optimization, and you know, there are some really fascinating technologies out there, not not all of them are very expensive either, that have significant impacts on our cellular biology.

Yeah, and we’re going to… we’re going to talk about that, and I… I think uh this is what I call the Golden Age of Healthspan. This is the age of the healthspan Revolution, uh, and I want people to understand what’s possible today, and and I think, you know, actually it’s funny because you and Tony Robbins… I’ve been in both of your homes… Tony’s a dear friend and a partner, and you’ve been there as well, and you’ve got the best toys on the planet.

Yeah, but we just collect, you know, the right toys. You know, some people collect cars… um, you know, we collect biohacking devices.

Yeah, well, we get… we… we’ll chat that now. Uh, what do we got here? And mine is colored red and yours is colored blue. Yeah, yours just needs to be charged. Mine… tell me that’s charged. This is hydrogen gas. I mean, probably of… of all… of all the biohacks… um, you know, under $30 a month, let’s say, I’m probably most excited about hydrogen gas and hydrogen water. Um, you know, this… this bottle will run you about $250, but you can get tablets… these Elemental magnesium tablets and drop them in… in a bottle of water and create high part per million hydrogen gas. Yeah, but I think it’s the most overlooked uh modality in all of biohacking today. So let’s dive in there because, you know, listen, I’m a scientist, I’m a physician, I’m a biohacker, and understanding fundamentally what’s driving hydrogen’s benefit… I’d love to understand it.

Well, there’s… there are lots of… of studies, and I’ll send them to you so you can link them in the show notes… on on hydrogen gas and its capacity to lower inflammation, improve circulation, um, to improve markers of methylation. There’s a really interesting study that I… I… I thought it’s probably worth mentioning… in… in… in the Journal of Experimental Gerontology. It was published in November of 2021, and was interesting about this study, and and we could talk about a lot of the other clinical evidence for hydrogen gas, um, which is a very prevalent gas in the human body. It’s… it’s harmless to human beings. Um, it is an antioxidant, right? It actually donates uh electrons, but uh historically and and evolutionarily we have reduced the amount of hydrogen gas that is in our diets, that is in our gut microbiome, that is in our water. Most of our water is very still now. If you scooped water out of a running stream, you’d find high part per million hydrogen versus bottled water, which is going to be… it… more stagnant. You… most of the time it’s been sitting for about two years. It’s a really interesting thing you could do it even at home. Um, you can order off of Amazon for a couple of bucks. You can order something called an ORP meter… oxidative reduction potential. You just go on Amazon, they’re between 12 and 15 bucks, and this is a millivolt meter that will actually measure the capacity of a fluid like water to either slightly cause oxidation or to reduce oxidation actually, and you want this number to be negative. The more negative the number, the more it has the capacity to reduce inflammation, and what you’ll find is if you poured standard bottled water into here, it would have a positive ORP, meaning it’s not reducing inflammation, it’s actually causing some oxidation um of about 150 to 200. The second you hit that button and add hydrogen gas or you drop an elemental magnesium tablet in that um glass of water and it effervesces into hydrogen gas, you’ll see the ORP drop to -400, 500, and this… this study in the uh Journal of Experimental Gerontology um back in 2021 actually looked at uh a six-month placebo-controlled um randomized group of…

Is this about the acidification of your body effectively?

Yeah, it’s about the acidification of your body exactly, because we know that we can’t change the pH of the body by drinking alkaline water. We can change the pH of the body by adding hydrogen gas, um micro bubbles of hydrogen gas to… to your water, because pH stands for the potential of hydrogen. It’s a… it’s a charge. If you want to change the charge in the body, change the charge with hydrogen, or you can do it by touching the surface of the Earth or laying on a PEMF mat and using a low gal current. But what’s really fascinating is most studies will look at healthy populations when they want to study recovery or traumatic brain injuries or post-surgical recovery. This particular study looked at 70-year-old um men and women over a six-month period of time, with a… some were just drinking regular water, the others were drinking high part per million hydrogen water, and and I really encourage your readers to… your… your… your viewers to… to look this study up. It’s incredible, and they… they actually used um uh well-known markers of methylation, one called TT… tetramethylcytosine deoxygenase to actually measure the impact on… on methyl… metion… so cellular methylation, which is a marker of cellular metabolism… how well your cells are actually taking nutrients and converting them into the usable form. Um, they measured uh choline levels in… in uh the left frontal over of the brain. They measured uh creatine levels in the right parietal uh area of the brain. They measured sit-stand ratios… so they found that it was an anti-arc… capen… measured several markers of inflammation: C-reactive protein, creatine phosphokinase, and others, and across the board, just simply adding hydrogen gas to the water improved all of these markers, including telomere length.

Amazing. Pretty… let me put some numbers against this. So how much hydrogen gas uh enriched water will you consume per day?

So in… in the mornings, I’ll use it instead of caffeine. So um, you know, a single tablet will get you to between nine and 12 parts per million um hydrogen. Some people can tolerate more than others. Um, I drink four or five of those a day… four or five tablets… four or five of those tablets throughout the day or four or five of these bottles throughout the day. It’ll mitigate all of the effects of travel. Um, it… I mean, if you want to do an interesting experiment, when you… when you wake up uh in the morning, take four or five of these Elemental magnesium tablets, um four or five of them… drop them in about a half a liter of water, about 750 mls of water, um in room temperature, and about 50 seconds… they… they will effervesce, and those micro bubbles will be in the water, and just drink that entire 750 milliliters of water, and just feel how switched on you are. Really… you… oh, you instantly switched on. You can feel the inflammatory cascade dropping. You feel more mentally alert, more clear, more cognizant. I mean, sounds like I’m just trying to sell hydrogen water, but I mean, technically I am. I’m just… I think of all of the biohacks that are out there, you know, you got a red light bed… it costs $119,000, and Elemental magnesium H2 tabs will cost you less than a buck a day. Yeah, um, and will completely change the trajectory… listen, so you know, I am again an experimentalist, and it is… does… do you have a visceral impact? Do you feel different? No question. Um, that you will feel different. I mean, the… the markers for sleep improved in the majority of these people. You found better deep and REM sleep, and you know, as we know, deep sleep is where we’re detoxifying our lymphatic systems… active… REM sleep is where we’re assembling memories and putting the cognitive actions of the day together with our subconscious and and our… our learning about… about carbonated water… how do you feel about that?

So CO2, I think, has the opposite effect. I… I… I… I haven’t seen any studies on carbonated beverages having an impact on inflammation, cognitive function, uh… joint…

Are you… are you warning people against using carbonated water?

I think if you’re going to drink water, you should drink still water with… with hydrogen. Um, I think there’s… there’s… the two shouldn’t even be in the same…

I’m… I’m going… so I have not been… and I will go and run this experiment for myself. I’ll… I’ll… I’ll link the studies, and you know, I even have a hydrogen bath at the house. I saw that when we were taking the tour, and and in fact… and in fact, the way you described it was such that… okay, if I have 20 minutes extra, I’m jumping in the bathroom.

No, no question. So what’s your… so this is… so we’ll show an image of this in a little bit, but uh this is a… this is a normal bathtub where the external hydrogen generator that’s bubbling hydrogen into the water, and you’re not consuming it, you’re just bathing in it. It’s going right transdermal. So you… you… it’s… it’s… it’s a hydrogen gas generator. You essentially fill it up with distilled water, and what it will do is it’ll take the distilled water, it’ll break it apart, it’ll throw the oxygen into the air, and it’ll put the hydrogen gas… we got this up on the screen here… that’s the generator… um… that… that is an absolute Game Changer. I think if I only had a single biohacking device, it would be a toss-up between that and a red light therapy bed, um… and red light… a good red light bed is going to cost you over 100 grand. That’ll cost you seven grand. So a hydron bath is… is grand. Yeah, um, and there are places where you can go and do this. I mean, so what’s the… okay, I’m still trying to understand as a physician and a scientist how this is impacting me. Well, when you say something is an antioxidant, what does that mean? What does it mean when blueberries are antioxidants? It means that they’re donating ions. It means they’re reducing inflammation. So… and and very specifically, if you can get hydrogen gas to go transdermal, which you can, you’re affecting microvascular circulation. If you look at the… our circulatory system, and a lot of people don’t realize that, you know, 70% of our circulation is not actually done by our heart. Nobody has a heart that’s strong enough to pump blood from the center of your chest to the tip of your toes through all the capillaries in your brain, your liver, your lung, your pancreas, your kidneys. The heart’s circulating about 30 to 32% of the blood in our circulatory system, and the rest of it is done by an activity called vasomotion or vasomotor. It’s almost… think of a snake swallowing a mouse, right? So… pumps the blood to the entrance of these very small capillaries, and then there’s a wave-like… parol… and you’ve got these valves in your venous system that only flow the blood in one direction… only flow the blood in one direction in this phase of motor activity… again, like a snake swallowing a mouse, and the mouse never goes back the other way… similar to how our intestinal tract works. There’s no pressure behind the intestinal tract. There’s a peristaltic motion to the… to the intestinal tract, and and this is the first part of our circulatory system to be compromised. If you think of 70% of our circulation is… is microvascular, and it… it needs a vasomotor or vasomotion activity in order to function. You could improve uh 70% of your circulation if you were able to affect vasomotor activity, um which transdermal hydrogen will… oral hydrogen will do the same thing. So I want to put some numbers on this again. So you said… okay, run the experiment… have 3/4s of a liter of water… put in four or five… the tabs down… see how you feel… instead of… instead of… instead of… next time you have a hangover, take four or five… I… I don’t drink, but if you drink and you get a hangover or you just have a headache… you have a migraine… you have a headache… you feel brain fog and you need to be awake… um… take four or five of those um H2 tabs… drop them in water… you can… you can get them at drinkh2tabs.com… like I said, it’s less than a buck a day… one of the reasons why I’m so fascinated by it… and drop those in there and just drink that 750 milliliters of water, and you’re… I… I promise you the worst of all headaches or worst of all hangovers will be gone in 10 or 12…

Amazing. So having done that, what do you do during the day? Do you continue this level of consumption?

Yes, just a single um tablet in… in 12 to 16 ounces of water. I… I… you know, I drink the Mountain Valley Spring water. It comes in the bottles, so it’s… I think 750 mls is half a liter. You can get the big liters too. Um, just put a single hydrogen tablet in there and just sip on that throughout… throughout the day. I’ll take four or five of those throughout the day. It’s… it’s an absolute Game Changer. Everybody… Peter here… if you’re enjoying this episode, please help me get the message of abundance out to the world. We’re truly living during the most extraordinary time ever in human history, and I want to get this mindset out to everyone. Please subscribe and follow wherever you get your podcasts and turn on notifications so we can let you know when the next episode is being dropped. All right, back to our episode. Let’s go back to the bath one second… and again, the technology is… is pretty direct and pretty simple. Uh, it’s bubbling in… you described to me a few of the athletes that you’ve treated, and it’s been a Game Changer for them. So who comes in? Why are you saying jump in the bath? How long are they in the bath for? And what’s the impact?

Um, your one that’s in public domain recently… uh… Jon Jones… you know, when he was preparing for his fight… I think he fought on November 16th of last year was his last heavyweight fight… um… he was intending to retire uh initially after that fight… I… I sat next to him at a UFC fight in the Sphere… and uh he leaned over and and he… and he put his hand on my… my leg… he grabbed my… I… like, “Oh God, you do whatever you want, bro,” and uh… and he literally looks… he looks me in the eye and he goes, “Are you… you’re a man of God, aren’t you?” And I said, “Yeah, yeah, I am.” And he said, “Um… I feel like God put you in my life at this moment. Um… I really need to talk to you,” and I… uh… and he’s put this out in the public domain, and um… when I spoke to him, he said, “Listen, I’m… for the last 12 or 15 years, I just wake up every morning… morning in excruciating pain.” I mean, he’s a Division I wrestler. He was… you know, beat up his body a lot. He beat up his body. He’s the greatest uh heavyweight… maybe… maybe one of the greatest fighters, according to Dana White, to ever live. Um… I… I believe that… and he’s an absolute gem of a human being. Um… he’s an absolute gem of a human being, but um… so I… a few weeks later, I flew out to his uh fight camp… and when he told me about how sore and achy all of his joints were… he was having a slow time recovering, and it was taking him a long time from waking in the morning till he could start to train, and he was only training five days a week, not six days a week. So he’s taking two days off on the weekends. Um… I introduced hydrogen water to him. So you’re thinking this is whole body inflammation… this is the whole body inflammation. If you think about where we get inflammation… you know, the majority of this is going to focus in the… in the areas of the least… the most compromised blood flow… so ligaments, tendons, um bones, cartilaginous surfaces, joints… areas where um, you know, the muscular tenderness… insertion… that area where you don’t have a lot of blood flow… you… you don’t get a lot of soreness in your um muscles if you’re used to training, but you get a lot of joint soreness… you get a lot of tendon, ligament soreness, and you get a lot of chronic inflammation in those areas. Well, if you can get hydrogen gas, which you can, to go transdermal and reduce that inflammatory process and improve circulation… which… there… I’ll also give you the links to some of the um uh, you know, grade 1, grade 2 spring strain injuries that they treat with hydrogen water versus the RICE protocol… the rest… ice… grass… and elevate… and um… how… hands down… transdermal hydrogen uh was more effective than ice and compression and elevation. But long story short, John texted me a few weeks later… he’s like, “Man, I can’t believe that I’m waking up not in pain. I’m adding a sixth day to my training schedule.” Of course, he went in… dominated his fight, which I take no credit for, um… and he’s announced that he’s going to continue fighting… um… and… and… and I… you… I gave one to Michael Chandler uh for his last fight. You know, I’ve given these hydrogen baths to a ton of people. My parents get in it every single day. Both my… my mother had bilateral… NE… so this is the equivalent of the… Cure… sort of… bathing in the…

I mean, it sounds like it’s… I’m so high on hydrogen. Okay, so nobody’s talking about… all right, so uh someone who has a high inflammatory load, and you can measure that… the technology is there, and absolutely… how often are they… and how long are they bathing in this?

25 minutes, once a day. So my wife, uh Sage, has uh an L5-S1 fusion… you know, shortly before we met, a little over 10 years ago, she was in a really bad car accident… ended up dislodging her L5-S1 disc… it degenerated, and she had to have a fusion. So they went in through an anterior approach… took the disc out… put a spacer in… Cav bone… ever since then, she’s had, you know, low back pain… radiculopathy… you know, all… all of the usual um byproducts of L5-S1 fusion. If she gets in the hydrogen bath for 25 minutes before she goes to bed, she sleeps entirely through the night pain-free. Um… if she doesn’t, you know, often she’s waking up, you know, in the middle of the night and having to go stretch or walk around or move it and then get back into bed. So uh I think these modalities where you can replace things like Methotrexate and meth prednisone and… prazone… and anti-inflammatories and corticosteroids… it’s poison. It’s… it’s so poison. I mean, initially it has any inflammatory response, but it will eat the joint like a termite.

Yeah, yeah. No, it’s… it will solve your problem in the near term and cause you many more in the long… I mean, I think cortisone injections probably ended more careers in professional sports earlier than they should have than maybe any other interventive therapy.

I want to… I want to jump into something that is um you’re passionate about and is fundamental, which is methylation. Um… just if you would take us from there. You know, I… I think methylation is… so what is methylation?

So methylation, also called one-carbon metabolism, is essentially the best way I can describe it is it’s the process that the human body goes through to take um all of the nutrients that enter our body… first, we have to understand that there’s not a single compound known to mankind… no vitamin, mineral, amino acid, fluid, protein, carbohydrate, you know, fat… nothing that we put into the human body that is used in the format that we put it in. Most of us know that we actually don’t eat to fuel our cells, we eat to feed our bacteria, and our bacteria eat to feed us, right? So there’s an intermediary between our food and our…

And just… just to… just to comment on that, right? Because it’s so important… the bacteria in your microbiome um determine how foods are digested, how medicines are digested… you know, if you’ve got the wrong… you know, how much exactly… it really is everything. You are a collection of 40 trillion human cells and like 100 trillion bacterial cells. Right? So companies like Viome and others help you understand how these bacteria are metabolizing what you eat and the drugs and what it… what works for you. I mean, a huge fan of Viome, and ultimately they are having a positive impact on methylation. Um, that’s one of the mechanisms that uh the outcomes of that test impact. And so if you… you… for example, we take in uh folate or folic acid… and this goes through a series of enzymatic reductions, and it eventually becomes something called methylfolate or five-methylfolate, which is the active form. So think… I’m going to steal one of your hydrogen tablets while we’re here because my battery is dead on this…

Oh, it is. Yeah. Um, and by the way, just for folks, you know, a methyl group is a carbon with… with four… with three hydrogen. Right? And uh… just to connect it back to our Space Cadets… when… when people are talking about when Starship is going to land on Mars, it’s being fueled by liquid oxygen and methane, which is a carbon and four hydrogen. So uh… you know, what’s incredible is in… in… in microbiology uh or in chemistry… the difference between uh the molecular impact of a compound by… by simply attaching or detaching a methyl group is night and day. It’s everything. So neurotransmitters are activated and deactivated… you know, we downregulate neurotransmitters… um… for example, catecholamines… you know, fight-or-flight neurotransmitters… there are genetic mutations that don’t allow people to um metabolize… to break down these neurotransmitters… and let me just back up… I want to touch on that because it’s an important subject, but this process of methylation or one-carbon metabolism is the process that our body goes to take something from the non-usable form and convert it into the usable form. So, for example, if you ingest folic acid… folic acid is useless. Um… it… it does not prevent neural tube defects. It doesn’t have any other positive effects in the body. In fact, folic acid is a man-made compound. Um… you can’t find it anywhere on the surface of the Earth. It does not exist naturally in nature. Folate does, but folic acid doesn’t. But regardless, folic acid and folate follow the same enzymatic pathway until they reach one of the primary genes of methylation called the MTHFR mutation… the infamous gene…

Can we say… we… we can… we can… and understanding your genome and understanding what your… 44% of your listeners have that mutation…

Yeah, it’s a problem. It is… it is a huge problem, and and and the consequences… meaning you’re not properly methylating in your body… you’re not properly methylating. So this is one of the main genes of methylation. So our methylation genes will say… um… okay, we pull crude oil out of the ground… M… H… right? But you can’t put crude oil into your gas tank, and the reason why you can’t is because the car doesn’t understand the fuel source. If you can refine crude oil into gasoline, now the car can accept that as a fuel source. The human body is no different. Our cellular biology does not use folic acid… doesn’t use folate… it uses the form of folic acid and folate that it is methylated into through the process of methylation, which is why I… you know, if you look at um this gene mutation… the MTHFR gene mutation, which is probably the most common gene mutation in the world… I mean, it’s estimated between 44 and 62% of the population has this… it doesn’t sound like a big deal to not be able to convert folic acid into methylfolate… until you realize that folic acid is the most prevalent nutrient in the human diet… right? In the United States, all of our grains… all… all white flour, bread, pasta, cereals… grains of any kind are sprayed with folic acid. We call it fortified or enriched.

Yes. So fortified or enriched foods are sprayed with chemical folic acid. So what happens if you put fortified or enriched foods into the body of somebody who can’t process it? Well, now they go nuts. So if you look at the history of postpartum depression, which, for the record, can begin during pregnancy, um… most of the women that get postpartum depression have the MTHFR gene mutation. They’re told by their doctor to take high doses of folic acid… 1500, 1800% of the daily allowance… to overcome the fact that they’re not methylating… and… yes… and this makes it worse… and all of a sudden… because I haven’t seen any um um RCTs… randomized clinical trials… um… linking elevated levels of pregnancy hormones to postpartum depression, but we will still blame pregnancy on postpartum depression, and and we should be blaming it on the high ingestion of folic acid. Now, if we gave those women methylfolate… if they took a methylated prenatal vitamin… their incidence of postpartum depression would collapse. Yeah. Um… it’s not the… it’s not the rise in estrogen… you know, going from… in the 400s during their normal menstrual cycle to going into the 4000s… like you see when they get pregnant… um… that’s perfectly normal… for estrogen to go up by 10 times… bind water in the interstitial space… well… the uterine wall… um… you know, increase the… the… the… the laxity of the… of the pelvic girdle… all those things that need to happen during pregnancy… but then you take 1500 to 1800% of the daily allowance of folic acid because your OB… OBGYN tells you to do that, and the next thing you know you’re… you’re… you’re going nuts… anxiety… anxiousness… depression… um… racing thoughts… I mean, there are so many people listening to this podcast right now that have that gene mutation… or they have a genetic mutation called… COMT… which is another bad one for women… women that have had hormone testing done… um… if… if they’ve ever had what I think is the gold standard of women’s hormone testing, which is called a DUTCH test… it’s… it’s a multi-hour urine test… you… on that test you will see this genetic mutation… COMT… catechol-O-methyltransferase… and the reason why this… this particular gene of methylation is important is because it determines the number of things… it determines how rapidly or how slowly you break down catecholamines… and why that’s important is that a rise in catecholamines is anxiety. Yes… there are so many people that are suffering from anxiety… and and you hold on to it… and… well, the point is that no one’s told them what it is. If… if you ask 15 practitioners what is anxiety, they will describe the characteristics of that condition. It’s a fear of the future. It’s a sense of impending doom. It’s a sense of fear without the presence of a fear. Well, that’s all of the things I’m feeling… what’s causing it? And the majority of people that have anxiety cannot tell you. It’s not like every time I step on a crowded elevator um and I’m claustrophobic I have a panic attack… or every time I walk to the edge of a 30th-floor balcony um and I’m afraid of heights I have a panic attack. These are people whose anxiety comes and goes seemingly without a trigger. I promise you, you should be investigating that gene… COMT… because you may be a slow… um… to break down… to downregulate these catecholamines… these fight-or-flight neurotransmitters… and as they rise, they do three things: number one, they create a weakened state… and so someone could be sitting… having a podcast just like you and I are right now… in a… in a very safe room with our friends right outside the door… and just… all of a sudden… be kind of overwhelmed with anxiety. Yeah… and now what they’re going to try to do is relate it to their outside environment… maybe… I’m afraid… they’re going to try… rise… ask… you can rationalize it…

Yeah… and they’re going to try to rationalize it by looking at a cluster of symptoms outside of their body. The truth is, if they understood that it’s a rise in catecholamines, they could start to take methylated vitamins… the complex of B vitamins… methylcobalamin, methylfolate… sometimes… SAMe… over-the-counter vitamins and and and nutrients that would then allow them to begin to methylate these neurotransmitters and downregulate them and and and calm that down. I mean, what I get so excited about is um this knowledge… this is… you know, this is William Gibson who said, you know, “The future is here… it’s just not evenly distributed,” and I… I think… I… I think that, you know, all of this knowledge and and… cheers to hydrogen water… take a sip… here’s a higher part per million than mine… now go ahead… but I think what’s fascinating is… we’re on the brink of a moment in time when all of this knowledge is uh knowable by anybody… not because they happen to have listened to this podcast or they’ve happened to listen to, you know, the Ultimate Human… work and media platform that you built… or your books or my books… it’s because they’ve turned on uh their AI Health uh system.

I agree… and that… that system… I mean, when you’re born, you had 3.2 billion letters that guide your life for the… it’s your software for the rest of your life… unless you do a CRISPR therapy um or gene therapy… it’s there… and so… um… that plus the… you know, I don’t know… hundreds of subdermal and wearables that are being developed will be able to know at any one moment in time what is your physiological state and um how to optimize it. And so you know, I’ve been having this argument recently… my sip of hydrogen water here, by the way… I happen to agree with you. I think the greatest intersection for humanity is the intersection of artificial intelligence, big data, and early detection. Um… and you know, specifically with respect to methylation… I mean, these are 300 billion um independent um metabolic transactions going on in… at any given moment… and… and… and AI can make sense out of it all… and… and we… you know, me… Sachs on our own

Leaf, they would contest the soil, and they would say, “You know what, Peter? There’s no nitrogen in the soil.” And then they would add that nutrient to the soil, and the leaf would heal. Human beings are no different. When we deprive the body of certain raw materials, you know, people get diagnosed with mental illnesses because, or mood disorders because they’re low on serotonin. But serotonin is methylated from tryptophan, which is a simple amino acid. And in order to methylate tryptophan, the amino acid into serotonin, which happens in the gut—about 90% of our serotonin in our bodies is in our gut—and if you don’t have it here, you can’t have it here. Um, travels up the vagus nerve. But what, what happens in the gut is um, deficiencies in amino acids and it deficiencies in the complex of B vitamins that cause this methylation process to occur, to convert tryptophan into serotonin or to convert phenylalanine and tyrosine into dopamine. And once you have the deficiencies in these neurotransmitters, now you can’t assemble moods and emotional states that require these neurotransmitters, so you get told that you have a mood disorder, um, or you have a mental illness, and now you’re down the bandwagon of um, chemicals or synthetics to reduce certain uh, synaptic uptakes of neurotransmitters when really you have deficiencies that are born out of a lack of nutrients. That’s why I’m so fascinated by methylation.

Yeah, and of course, methylation of our DNA is also how we control what genes are on and what genes are off. Yeah, it’s also how we know that genes are not necessarily our destiny; they might be our predisposition. I love this stuff. Uh, you know, let’s, let’s turn to some of the fun toys in your bedroom and your, your incredible penthouse apartment. So this is a, a, a red light bed, and there are a multitude of them, and like you said, this typically will run you 100K or so. Talk about this.

Um, so I’m a huge, huge fan of red light therapy. Um, let me also tell your listeners you don’t need to run out and spend 100 grand on a red light bed. Um, you know, you can Google around, and there are red light panels; there are red light panels; uh, uh, there are smaller red light beds; uh, there, there are other ways to get red light. You can usually find a clinic in your area that will allow you to use these things on a membership basis or, um, at, at the very least, you can expose your skin to sunlight, um, because we are very photovoltaic beings. You and I were just, were sitting here in Southern California, and we were both outside, like, just, you know, soaking in the sun. We just did it, just now.

Exactly. Um, and so I always, so what do you think? What do you normally, when someone says, “Hey, why, how often are you hanging out in a red light bed?” Uh, how long, and what does it do for you? Ten minutes a day, every day, um, seven days a week if I, if I can. Uh, you know, I have it in, uh, in a separate room in the house, and I have this sort of pattern that I go through. I wake up in the morning, brush my teeth, splash water on my face. What time do you wake up? Um, between 6:00 and 6:30 latest, usually trying to be up with, you know, first light. Uh, so really intentional about trying to, trying to get first light. In fact, we’re out in LA now, and we rented an Airbnb, and I actually found a ladder behind the Airbnb, so I put it up over the—on there are three roofs on this house—and I put it up on the low roof, and I climbed up on that, then got on the second one, then got on the third one, and I did my breath work up there on the, on, on the rooftop in the morning, ’cause it’s nice and cool here; it’s like in the high 40s. So I just took my shirt off and, and uh, did some breath work up there. But, um, but exposing your skin to, to, to sunlight is, is—I don’t want to say the poor man’s red light, but it is the best way to get light therapy. But, but red light does a number of things. Um, there, there are a number of therapeutic wavelengths. First of all, uh, light can be very damaging or can be very therapeutic in the body. If you look at the light spectrum, you know, starting with something like x-ray, which is light—these are very damaging—um, moving to UVA, UVB, which are the damaging rays from the Sun that, that, that cause uh, skin cancer. And then there’s a very narrow spectrum of light, very, very narrow spectrum of light, which is the visible light spectrum: the reds, the orange, yellow, green, what is it? Blue, indigo, and violet.

Yes. And ROY G. BIV.

Yeah, ROY G. BIV. I remember that still from, from, from biology. That’s what I was playing in my head. Yes, ROY G. BIV.

Um, and then after that, you get into infrared and near infrared. And, and what happens in these wavelengths from red to infrared and, and this near infrared is that when these wavelengths of light pass through the body, one of the most powerful things that red light does is it goes into your mitochondria, and it kicks out a gas called mitochondrial nitric oxide. And so it kicks out nitric oxide, and it forces oxygen to dock. So there is a part of the Krebs cycle inside of the mitochondria, uh, uh, where oxygen docks called cytochrome c oxidase. And you want to think of cytochrome c oxidase as a one-arm man; he can either shake hands with nitric oxide or he can shake hands with oxygen, but he can’t do both. If you can get cytochrome c oxidase to bind oxygen, you can upstage the mitochondria; you can improve its production of adenosine triphosphate, the ATP. Um, you know, we know that aerobic respiration yields 36 ATP; we know that anaerobic respiration yields two ATP. So an ATP is what really powers human beings. Taking me back to seventh grade and to medical school—it’s all, it’s all about the mitochondria. So, not to get overcomplicated, but what red light will do is it will kick out this gas and force oxygen to dock, so that is already a battery charger for your cellular biology; literally charges you up like a battery. Um, we also know that certain wavelengths of red light are—these are mostly the visible um, spectrum of lights because they’re very superficial—are excellent for collagen, for elastin, for fibrin. Um, it also, back to the vasomotor uh, circulation and vasomotion, it has a positive impact on both vasomotor and vasomotion. And there are numerous clinical studies in, in the public literature on PubMed, and I’ll, I’ll have my team link them here, um, on uh, the improvement of eyesight because it improves microvascular circulation to, to, to the back of the eye. There are several cataract studies involving…

When you’re in a red bed, in a red light bed, uh, do you need to shield your eyes or are you okay?

I leave my eyes open. You get these red light beds will have all four and sometimes five wavelengths. Um, I, I use one called um, LumiPod Pro. Um, it’s got 45,000 light diodes. Um, it has five wavelengths of light. Uh, a typical session is 10 minutes; you could do it for 20 minutes. Um, and you’re not only improving collagen, elastin, fibrin in your skin, you’re improving microvascular circulation; you’re reducing inflammation; you’re charging up your mitochondria. I mean, I, I think that, and and the hydrogen nanobath would be my, my two go-to when I’m…

So I use a red light panel, um, because I’m also got a red light cap on my head for stimulating your circulation and hair growth. I’m, I’m using a red light oral device as well. I’ve seen those, like it looks like a tongue device. It, it, it basically is that, by Neuronic…

No…

Neuronic makes these helmets that actually go transcranial.

No, this is, uh, this is both red light and blue light; this is impacting uh, the pathogens in my mouth, right? I’ve gotten so focused on oral health.

Yeah, right. Because people should know your mouth and the, the bacteria and, and other pathogens in your mouth are a, a, a capillary away from your brain. Yes, and not too many capillaries away from your heart. And what’s interesting is some of the, some of the bacteria that create calcification—hydroxyapatite—we find in, um, in cavitations in the mouth, but we also find them in, uh, calcium in the heart. And I think most people think that these, these hard plaques, uh, like our bones are calcium, and they’re actually not; they’re, they’re calcium combined with, with phosphorus, which is forming something called hydroxyapatite, very similar to what’s, what’s in our teeth and, um, and in order for that to form, you need something like an osteoblast that creates bone, or you need a bacteria that can, that can combine calcium and phosphorus to form this hydroxyapatite, which you find in citations in your, in your mouth. I’m a huge fan of, of getting, you know, seeing a quality biologic dentist, if you’ve had a root canal for sure, and getting that cleaned out, testing your, testing your uh, oral microbiome to understand, do you have any of the pathogens there that are really…

I’m actually waiting for a tooth right now. And not to be gross, but…

Yeah, exactly. See that guy? Yeah, waiting for it in what respect?

Reg… no. So I had a root canal here, um, and I, I went to a biologic dentist named Dr. Jagar Gandhi. Phenomenal biologic dentist, as far as I’m concerned; he’s probably the best in the country. I cracked a tooth one day in the back of my mouth on the other side, and, um, I called him, and I was, I, I hate the dentist. Yeah, who means who loves dentists? I mean, honestly, sorry, Dr. Gandhi, uh, but, um, and I, and I called him and I said, “You know, dude, I’ve got to come up and see you, man. I cracked this tooth in my mouth.” And, um, he goes, “Take a picture of it.” And so I snap a picture of it, and, um, he goes, “Oh, that’s your 19th tooth meridian.” He goes, “Do you ever get uh, left anterior shoulder pain?” No. And I swear to God, I did a whole podcast with him; I was so, I was so fascinated by it because I’m pretty like, woke, like what’s going on in the wellness world. I watch everything that goes in my mouth; I’m in red light; I’m drinking hydro; I’m doing all this stuff. And, and I go, “You know, that’s, that’s weird. I actually do get left anterior shoulder pain.” I thought it was like a bicep tendinitis or something; it wasn’t like enough for me to go to the urgent care or something. And then he said, “Do you ever get left lower lobe lung pain?” He was that specific. I go, “Dude, you are freaking me out. Whenever I do HIIT cardio, I have a catch right here in my rib.” I just thought it was like a runner’s something. And, um, um, and then he super freaked me out because he said, “Does your left toe ever go numb?” No. Come on. I, right hand to God, he—and it didn’t go numb, but it would, it would tingle and itch, and my wife used to tease me because I would take my shoe off, and I would itch my big toe, and then I would put my shoe back on, or I’d be talking to somebody, and I would just tap it.

Yes. And because it would feel like it was going numb. And he goes, “Yeah, that’s your 19th tooth meridian.” And he sent me this chart, and it mapped to the meridian. He’s like, “Yeah, you, you, you had a root canal in that tooth.” And I was like, “I did actually.” Um, and he said, “Come up; we’ll do this cone beam x-ray; we’ll, we’ll check for cavitation.” So I went up, and they did this 360 x-ray; he actually found several of them, um, but two of those were in root, in root canals. Yeah. Um, and I, I posted this on my Instagram because I was so fascinated by what he was able to predict by this meridian. And then, um, when he took my tooth out, there was this little balloon on the bottom of the tooth—this is getting gross, so if you’re, if you’re squeamish, caution for the viewers—caution for the viewers. He took a—I go, “What is that?” He goes, “Oh, that’s a cavitation; that’s a pus-filled sack with bacteria and parasites.” I said, “No way! I have no pain; I have no symptoms; I have no inflammation; I have no gum bleeding; nothing.” So he pops it, puts it on a slide, and we dark-field it in his office, and I, I, I, I posted this video; you could see my macrophages going after the parasites, going after the bacteria. I mean, I, I was horrified by it. And so he cleaned it all out, ran red light in there, put uh, platelet-rich fibrin…

Yeah, let’s just stop right here and tell people, uh, your, the health of your mouth is so critically important, right? So you’re 50, what, now?

54.

54. I’m 63, and uh, I wish I had started paying attention even earlier in my life. Yeah, uh, it is, people ignore it; they go to the dentist because they have to, when they have a, you know, that’s fine, but there is so much more that you could be doing in terms of, of, of, you know, using an electric toothbrush. Uh, I actually have a device, flossing—I actually uh, have a device—it’s called Proclaim; I don’t know if you know this—you go in your mouth, gets scanned, and it’s a mouthpiece that has a jet in between every single tooth, and so it is like high-energy, high-speed water-pick flossing in 30 seconds. You put this in your mouth—I love it—you put this—I know you put this in your mouth—you know, you bite down like you would a mouthguard, and like this whole container of water just gets pumped in through all of those, and your mouth is, is clean. So I mean, it’s, it’s amazing, right? And then uh, there’s another uh, uh, product that they changed their name recently, which is a toothbrush with a very similar structure, but it’s with all of these brushes that you basically clench down on it, and it brushes everything. So I mean, I remember I knew Jeff Bezos 45 years ago and uh, when he was purely a space cadet before Amazon. And then he and I reconnected, and I was talking to him about XPRIZE and space and, and all, and one day I said, “Hey, is there any chance and come and speak at this event?” This like 20 years ago. And he goes, “Peter, um, I’m so short on time; I’m trying to optimize my, my toothbrush time, my toothbrushing time.” And I said, “Okay, I, I get that, but this is what you’re actually doing; you’re able to like, you know, take those…”

Yeah, 15 minutes, 10 minutes, and make them much more efficient. The technology is there—technology—but more importantly, going to a biologic dentist to check out the floor and front on your mouth—highly recommend it. So, so then this tooth, which I’m waiting on, he, he also pulled this one, cleaned it out, red light…

Ozone gas.

Yes, gas. Exactly, which is wild. When they take the tooth out, it doesn’t even bleed. Huh. And that’s a bad sign. And so he runs the ozone gas and the red light and, and increases the perimeter of, of, of the hole until you get fresh red blood. Then he packs your own platelet-rich fibrin in there, you know, your own, your own platelets, and he puts the, um, stitches it shut; the bone grows shut, and then he puts the, believe it’s a porcelain implant. I mean, he doesn’t use any metal. And now I just got to go back up and have the tooth put on there. Um, but I, I, I think it’s one of the best things I ever did, and I just can’t believe that that just flew by me. But he also uses red light—not the full red light bed, but he uses those uh…

Red light…

About 13 years ago, I had my two kids, my two boys, and I remember at that moment in time, I made a decision to double down on my health, uh, without question. I wanted to see their kids, their grandkids. And really, you know, during this extraordinary time where the space frontier and AI and crypto is all exploding, it was like the most exciting time ever to be alive, and I made a decision to double down on my health, and I’ve done that in three key areas. The first is going every year for a Fountain upload. You know, Fountain is one of the most advanced diagnostics and therapeutics companies. I go there, upload myself, digitize myself—about 200 gigabytes of data that the AI system is able to look at to catch disease at inception. You know, look for any cardiovascular, any cancer, any neurodegenerative disease, any metabolic disease. These things are all going on all the time, and you can prevent them if you can find them at inception. So super important. So Fountain is one of my keys; I make that available to the CEOs of all my companies, my family members, because, you know, health is the new wealth. Uh, but beyond that, uh, we are a collection of 40 trillion human cells and about another 100 trillion bacterial cells, fungi, viruses, and we, you know, don’t understand how that impacts us. And so I use a company and a product called Viome, and Viome uh, has a technology called metatranscriptomics. It was actually developed uh, in New Mexico, the same place where the nuclear bomb was developed, as a biodefense weapon. And their technology is able to help you understand what’s going on in your body, to understand which bacteria are producing which proteins, and as a consequence of that, what foods are your superfoods, are best for you to eat, or what food should you avoid, right? What’s going on in your oral microbiome. So I use their testing to understand my foods, understand my medicines, understand my supplements. And Viome really helps me understand from a biological and data standpoint what’s best for me. And then finally, you know, feeling good, being intelligent, moving well is critical, but looking good—when you look yourself in the mirror, saying, you know, “I feel great about life”—is so important, right? And so a product I use every day, twice a day, is called OneSkin, developed by four incredible PhD women that found this 10 amino acid peptide that’s able to zap senile cells in your skin and really help you stay youthful in your look and appearance. So for me, these are three technologies I love and I use all the time. Uh, I’ll have my team link to those in the show notes down below. Please check them out. Anyway, hope you enjoyed that. Now back to the episode. Let’s jump into saunas. Um, you know, I just bought a uh, a portable infrared sauna, which is, you know, the size of a chair that I can hop into; you kind of zip it up; you, you zip it up. But I mean, this is a full-on sauna. Talk to me about your sauna practices.

So sauna is one of the best ways to activate your detoxification pathways. Um, you know, if, if you talk to any functional medicine practitioner where they’re trying to detox somebody from anything—mold, mycotoxins, pathogens, um, you know, bacteria, metals—they will tell you that sauna and sweating—both infrared and near infrared, I’m sorry, both infrared and dry sauna—has to be a part of your, your regular routine. Um, so I’ll usually um, put a liter of fluid through myself after I get out of the sauna. I have a dry sauna. Um, I, I actually have my parents, um, who’ve been staying with me for several weeks.

Yeah, you did. That’s right. They were there when you… there. They’re still staying with me. So Captain John Brea and Judy Brea. Um, Mom has bilateral knee replacements, um, and Dad had a very bad boating accident years ago which left him with hemiparesis on one side of his body. So both of them are rather deconditioned from a physical standpoint. And, um, so I was following Dr. Otto Warburg’s work in multi-step oxygen therapy or EWOT—exercise with oxygen therapy—and since it’s difficult for them to get their heart rate up, I’ll put both of them in the sauna, and I’ll run a nasal cannula under the door, and, and they’ll just breathe high-PPM oxygen, um, for about 20 minutes. And the difference in their cognitive function, even, even immediately after getting out of the sauna, they would both tell you, is, is, is night and day. My mom’s a chatterbox, and so is my dad. You just feel clear and clean, cognizant, awake. Um, so my wife and I do sauna regularly. And, and now, how long? How many days a week?

Twenty minutes minimum, three times a week. Um, it’s just something we really like to do; it’s right next to our bathroom. Uh, and so she and I will very often end the day in there together. And, um, and then I’ll get out of the sauna, and I’ll do just a 20- or 30-second cold plunge. Um, not a long cold plunge, uh, but a 20- or 30-second cold plunge, and I’ll dry off, and you know, that’s proved to be quite a little sleep hack for me. Um, I mean, people could do it with a contrast shower, too—oh, hot shower followed by cold shower—um, especially if you’re one of those people that ruminates. Um, if, if, if your environment quiets and your mind wakes up, and you have ruminating thoughts, or you just replay the day, or you go through your grocery list and all of that. But sauna is excellent for detoxification and steam room…

So steam room is, is—if you had to choose between sauna and steam room—if I had to choose between sauna and steam room, I would probably choose sauna, and here’s why. Um, I think most commercial steam rooms are not filtering the municipal water when they bring it into the steam room, so you’re vaporizing gas, fluoride gas, microplastics, pharmaceuticals, um, polyfluoroalkyl substances—these PFASs—which are very, very high in the municipal water supply in Miami. So unless you are certain that they are running that through, preferably like a four-stage reverse osmosis filter or some other type of, of micron filtration, uh, which I do at the house, I don’t trust a lot of steam rooms. Um, so my preference is not to breathe vaporized fluoride and chlorine, but, um, but it can be um, even more effective at heating the body up than sauna. Remember, water is 29 times more thermogenic than air.

Yes. And what you mean by that is its ability to take away or provide heat.

Yeah, that’s right. Like you can die in 72-degree water. Heat capacity—you can’t, you can’t get hypothermia in 72-degree air, right? Your body can maintain the temperature gradient. So I have both steam and, and, and sauna, but I, I, I actually use a reverse osmosis and charcoal filter when it comes to the house sauna closet. Yeah. And then, then I have another step-down filter. I like—I’m such a psycho—but, and then that’s a cold plunge; that’s one of my favorites. You know, um, here’s the thing about cold plunging: I, you know, there’s no evidence that I’ve seen that colder is better or longer is better. Three minutes minimum, six minutes maximum, 50 degrees Fahrenheit is plenty. Um, you know, you get a peripheral vasoconstriction, uh, which, you know, drives all the blood into the core—liver, lungs, pancreas, kidneys, up to the brain. You also get a really interesting activation of brown fat, uh, which is different than, than white fat; it exchanges a—it’s our thermostat—you know, essentially exchanges a calorie um, for a measure of heat.

So you mean to tell me that when I get cold, my body’s going to use calories and turn it into heat?

Yes. There is a cost to having your body temperature return to normal. Let’s not forget, if you’re in 50-degree water, um, and you get out and you’re in 70-degree air, your body’s still going back to 98.6. So how, how does your body continue to raise your, your temperature? There’s a cost to that; it’s not free. And the cost is calories—increased caloric expenditure. And, and um, so brown fat turns calories into heat. But, and by the way, one of the things that I think is important, um, is the small hacks of increasing your, your caloric expenditure, right? So I’m going to point out to those of you who are joining us on, on YouTube here, uh, Gary’s wearing this beautiful little vest that looks like it’s just a normal vest, but it’s a, it’s a 10-lb, 10-lb or 10-kg…

It’s 10, 10-lb, 10-lb vest. I’d probably notice, but 10-lb vest.

And I tried it on, and it really felt, you know, slightly heavier; it was like feels kind of snug. If you ever use a weight vest, it feels good. And you said that, you know, your estimate on your particular muscle mass and caloric expenditure that you’re thinking wearing this during the day…

Close to 600 calories if I wear it for the 10–12 hours, which, like I said, it’s a Big Mac; it’s significant.

Yeah. I don’t say wear a weight vest and get a Big Mac. Um, but you know, I, I uh, I’m a big fan of rucking, too. And, you know, I’ve got the—I think it’s Rogue—where you put the plates in the front and the plates in the back, but it kind of hangs over your shoulders. That’s a actually a a large commitment. This was super easy, super bulky. Um, these guys at AON, uh, A-O-N—I think they pronounce it Ion—they make these weighted vests that, that actually zip snug to your body; you can use during workouts, um, or they make more decorative ones you can just wear if you’re just walking through the airport, and it looks…

Trying… I’m traveling; I’m just trying to biohack things. I’m like, “Well, I’m going to be walking anyway; I might as well add weight.”

Yeah, you know. And by the way, one of those, the mental hacks here, and I keep on reminding people of this, is it’s like, take the stairs instead of the escalator. You know, if you need to park, if you’re having a difficulty finding a parking spot, park two blocks or three blocks away, and think of it as free exercise. You’re not paying a trainer to give you…

Yeah, those little…

My wife and I play that game at the airport; you know, we always try to find the stairs and not the escalator. What, what’s amazing is they have those moving walkways, and they’re actually called moving walkways, but most people turn them into moving stand-ways, yeah, and they just get on them, and they just sort of ride, you know, and they get off and walk four feet to the other one. Lazy bastards.

All, I actually love a good walk in the air before I get on the plane.

Absolutely. And so I will not go on the moving walkways; I, I will, I will actually try and keep up with everybody by walking faster on, on the side. So cold plunge. You said something interesting a second ago, which is um, it doesn’t have to be that cold; it doesn’t have to be that long. So if cold is not better, longer is not better. I mean, so if you’re, if you’re in the shower—in my typical practice, because I don’t have a cold plunge…

I thought you saw one out there.

Yeah, well, I do, but this is—I’m, I’m not always here at, at the studio. But there is, there’s a, there’s a cold plunge, um, right there. But I will, you know, take my hot shower, and then for the last 60 seconds, take it to as cold as possible.

Absolutely. That’s the other thing. I mean, again, you know, all these modalities are great, but, but people can take um, Tupperware containers, freeze large blocks of ice in, in their, in their freezer, throw them in their bathtub. Um, it’s good for about three days; if you got up a couple of these big blocks, they’re—your water will stay cold for three days, you know, and it’s a great way to make a cold plunge because, you know, even if you’re just buying ice from 7-Eleven, eventually, that’s, that, that adds up. Uh, so you can, you can freeze these; that’s a great hack. Yeah, you freeze these, and you drop them in, you know, just like, say, you, you can access a lot of these modalities—you know, sunlight, grounding, breath work, um, uh, you know, cold plunge—for little or next to nothing. But the other thing that, you know, I was about to mention was the um, release of something called cold shock proteins, which are specialized proteins released from your liver. There’s a lot of research now looking at cold shock proteins and a lot of these benefits, and uh, there’s a few in particular—Lin28a and uh, Lin—capital L I N 28b—um, which are implicated in uh, the improvement of insulin resistance, um, making you more sensitive to insulin. Um, they scour the body of free radical oxidation. Uh, there’s some evidence that they improve protein synthesis, you know, the rate of muscle repair. And so just think, in three minutes, you get a dopamine spike, a peripheral vasoconstriction, uh, you know, an activation of brown fat, and a release of cold shock proteins. Three minutes and get out. I mean, and that’s why you feel—I, I call it my drug of choice, ’cause you, you, you feel so good for so long, um, and, and you don’t have to get into 35-degree water, and you don’t have to go for 12 minutes. I see people online, you know, going underwater with a snorkel in 37-degree water; that’s a macho move. I’m like, “Man, that’s just not a good idea. Your brain’s only this far inside the surface of your skull.” All right, so I want to talk about hyperbaric oxygen, um, because I’ve seen and heard miraculous results and, and mixed results, and I’ll tell you where that’s coming from. And, and so uh, there’s, there’s a therapeutic level and a hobbyist level, right? So let’s talk about… So this is a hobbyist version. Um, I actually have one of these soft-shell chambers. 1.3 atmospheres; it goes to about 1.3, 1.4. The hobbyist will go about 1.3 atmospheres, which is good. Um, but as I’ve gone deep down the rabbit hole of hyperbaric, and I’m sold on hyperbaric, I’m actually building my podcast studio inside of a hyperbaric right now.

Love that.

So February, middle of February, I’ll have uh, the, the first ever podcast studio inside of a hyperbaric. If you’re on The Ultimate Human, we’re going to be doing in, in a hyperbaric. Um, but if you look at the majority of the research on, on, on hyperbaric oxygen therapy, it’s done at two atmospheres or greater. Yes. What I found, uh, sadly, is that um, most of the soft-shell chambers will borrow that research, um, you know, as um, outcomes for soft-shell chambers. Now I have a soft-shell chamber; I’m not on those guys. Um, but you know, it, it mimics deep sleep; it can actually be uh, not a replacement for, but an adjunct to, you know, poor sleep. My, my wife, all the time—she does not get a good night’s sleep; she’ll wake up, and she’ll go spend an hour in the hyperbaric, breathe 92% to 95% O2 through a nasal cannula, and then you are switched on. Um, if you’ve ever done hyperbaric therapy, even at 1.3 atmospheres, you feel amazing after you get out of there, and you, you’ve, you’ve been breathing that oxygen, but the compressed gas at, at, at two atmospheres. Um, and I’ve just started to go way down the rabbit hole in hyperbaric uh, oxygen therapy. I have one of the top experts in the world coming to the house to help me design some protocols because my, my concern is that I become adaptive, right? Um, and you know, we can adapt to altitude; we could also adapt to hyperoxemia.

Sure.

And, um, I also use hydrogen uh, tablets to offset the oxidative uh, you know, free radicals from…

Hy—which is one of the questions I was going to ask because you’re driving oxygen, which is an oxidative force, into your body.

It is. Yeah, it is an oxidative stressor. And so, but a hydrogen gas offsets that. So I do another one of those hydrogen bombs, you know, four or five of those H2 tabs, uh, I’ll drop those in water, I’ll put down 750 milliliters of water, and then I get in the hyperbaric, and man, I’m telling you, you feel like you took a Limitless pill; you’re so cognizant, so clear, so awake, so alert. Um, it comes very close to mimicking deep sleep. And so if you’re sleep-deprived, you know, hyperbaric—it’s excellent for wound healing; it’s excellent for circulation; it’s excellent for cognitive function. I put both of my parents in, in a hyperbaric chamber. I’m super excited about the podcast studio; this will have, you know, AI…

I don’t know why you don’t sleep in there. Michael Jackson used to sleep in…

Well, he’s, he’s not doing so well right now. He’s not doing so good. But, but interestingly enough, was in Israel; I met the team that… that’s where all the good…

Right. And, um…

Good, good cognitive function work. Yeah. And, and a whole slew

Also, get the benefit of the oxygen, but this will—this has also Rife frequency in it. Um, so you put your feet on Rife frequency plates, and you can select different modalities. So you could select, you know, thyroid, immune system, adenoids, what have you, but it runs carbon dioxide to dilate the blood vessels and dilate your pores, and then it will run transdermal ozone, and that goes right transdermal, right into the bloodstream. And I’m telling you that will shift you from a sympathetic to a parasympathetic state like nothing you’ve ever done in your life. You are so relaxed, relaxed, and Zen, getting out of that thing. That’s great.

All right, we got the Balancer Pro here. Those are just uh, very expensive compression gear, but they work. Okay, so this is a vascular muscular compression. Yeah, so this is mainly lymphatic compression. You know, a lot of the compression gear, people think that the more pressure the better, and that’s absolutely not the case with with lymphatic circulation. You know, there’s there’s no pressure again behind the lymphatic system; it’s a static system, so it needs muscular contraction in order for it to flow, so it needs motion and activity. So these Balancer Pros, they’ll start at your feet, and they’ll they’ll actually um, and very rhythmically and gently, and the pressure will slowly increase; they will um, push all of the lymphatic fluid up into—two paste through a—yeah, like two paste through a tube. Yeah.

Um, all right, PEMF—pulsed electromagnetic field therapy. Um, people swear by it, and I swear by it. I have one in my—so PEMF, pulsed electromagnetic field. So this is one of those modalities where you can use high-frequency PMF, which it can actually cause a muscle contraction and and is really good for muscle spasms, uh, you know, muscle soreness, uh, recovering from joint injuries, but as a daily modality, um, you want to use something called a low-Gauss PMF. Um, Gauss, which is a current measurement, similar to the surface of the Earth, has a low Gauss; it’s a—yeah, magnetic field measure—yeah, magnetic field, sorry—uh, measure. And is this go under your—under your sheets of your bed? Yeah, so you can put it right under the sheets of your bed; you pull the sheets over top of it. Um, might have an eight Sleep mattress; it’ll blast right through that, and what it will do is it will just run a low-Gauss current uh, through the body—through low-Gauss field, sorry—through the body. And what this Gauss field does—and you can measure this—you could dark-field your blood; um, you can uh, just like you can measure the outcome of red light bed, you can actually do nitric oxide strip testing before you get in and before you—and when you get out, and you can prove that your red light bed is working. You know, you get in—before you get in the red light bed, just put a nitric oxide test strip in your mouth, which you can get for like six bucks on Amazon; it’ll be like a pale pink. Yeah, and then you’ll lay in the bed for 15 or 20 minutes, wait about 10 or 15 minutes and do it again, and you’ll see that your nitric oxide levels—I do—I have those bedside. Yeah, but but this will—what this will do is repolarize the surface of your cells. So if you—I think they call it rouleaux—when the—when the red blood cells start to stack and stick together—when—when—when cellular surfaces have similar charges, they repel; um, when they opposite charges, they attract—everywhere that they touch, you lose surface area to exchange with the outside environment. So now you’re impairing this cell’s capacity to eliminate waste or repair or detoxify um, or regenerate. So what—what a pulsed electromagnetic field will do is it will restore that surface polarity, um, and you can see this pre- and post-PMF. By the way, you can see it pre- and post—uh—uh—grounding as well. People think that grounding and earthing is is like Voodoo science; it’s not. If you can’t—if you don’t have the budget for a PEMF mat, take your shoes off and touch the surface of the Earth. Yeah.

Um, what do—one of these—put—sent you back here? So this one will run you about five grand, um, uh, but it really works. If you look at the coil, they go from the top to the bottom—from the top. So I have an eight Sleep mattress, and this will—this goes underneath the—it go right under the eight Sleep because the eight Sleep—the thing I love about the eight Sleep—there’s no EMF in that; it’s just the coils in the bed. Um, I get markedly better sleep when I use the the eight Sleep too. Um, and again, like you, I’m just trying to condense time—like how can I biohack these? I can lay down; I can run pulsed electromagnetic field, which is mimicking—this will be on my—my buy list after this. Yeah, for sure. Um, and and then the—and then the uh, eight Sleep. But these are—these are—these low-Gauss current mats are are phenomenal for uh, uh, for restoring cellular polarity. Fantastic.

I’ll just add a few of these. Um, uh, I’m usually—I’m usually wearing a continuous glucose monitor, and it’s not—it drove me crazy when I wore CGM, so for no other reason than to gamify what I eat. That’s basically it. You got used to seeing what—yeah. So it’s—I—my game is—and so you know, I’m not wearing it today; I should have, but um, uh, the battery ran out two days ago. I’ve got a stack. I moved out of my house because of the, you know, the fires. Wow. Oh yeah, no, I was on the edge of the Santa Monica and Pacific Palisades, so the house is now—I’ve been out of it for three weeks, uh, and we have uh, remediation to get all the the smoke there out. Anyway, long story short, so a lot of my stuff is is there, but I wear it simply to see how low I can keep my blood glucose from spiking throughout the day. I mean, that’s basically it, and it’s fun to see that and fun to play that game. Yeah, and you see what happens if you eat high-glycemic carbs, things like that. It’s like—it’s like—not—it—it’s interesting, right? Because I will say, okay, if I eat that, I’m going to spike it, and I’m not going to be happy about that, so it just creates a hack. Yeah, it’s like—we’ll talk about the Oura ring in a second, which I’m wearing, and the only—you know, an Oura ring is not going to help you get to sleep uh, better, but it at the—in the—at night when I’m going to sleep, I know if I—so I’ve pretty much given up most alcohol; I’ll have like a sip of red wine, like that, but if I should ever drink a glass of alcohol, my Oura score will will plummet. Or if I go to sleep—so true—if I go to sleep late, um, it—it—so CGM for me, it’s super easy, fun, gamify what I eat. Here’s the Oura ring. I got uh, last night in preparation for you; I got like uh, one of my—my high scores at 95. You did nice. So one of the things that’s um, that’s what I—what I get here in—ter—uh—what time did you go to bed? I went to bed at 8:45 p.m., and I tell you—I tell you that is everything; it is everything; it’s—it’s—it’s how—everything that we discussed, yes, matters little compared to sleep. It’s like when I go to sleep impacts everything fresh to day, and you—I used to be a night owl, where I’d be up till midnight, one or two o’clock, and you know, my wife and my friend’s like, you know, you don’t go out and party with us. Well, you know, it’s—yes, true, but I get up at 5, and I write—M—and uh, so last night I got an hour and a half of REM and uh, an hour and 15 of deep sleep. You get up and you write, or you ride? You said I write. Oh, you’re right. Yeah, I write. It’s like my first two hours are mine—M. Um, so good. But the Oura ring doesn’t give you good night sleep; it does gamify the fact that if I eat too late, if I drink too much water too late, have to get up and urinate, if I go to sleep too late, if I—it’s like I’m going to have a shitty score in the morning. Yeah, you know that if you eat too close to bedtime, if you drink at all, uh, you know, any of those things. So have you—so I get an A sleep score on my eight Sleep mattress as well. My eight Sleep always gives me hundreds. My Oura ring is a harder grader. Yeah, same with—same with Whoop; it’s usually—they’re usually within—I wear a Whoop; I—I actually—I’m charging it right now. Um, the uh, I think Oura and Whoop both do the same thing; you can disconnect the Bluetooth at night, and then it will upload in the morning, which I like. Um, but the uh, the eight Sleep is always slightly better than my Whoop, but usually is not demonstratively; it’s like 96, 97, 96, 98; it feels like it’s a—it grades on a higher curve. Okay, but I was—was like one of the earliest investors in Oura when it first came out, and the Oura ring used to be this giant, like Scarab-size thing on your—on your finger. Beautiful. That’s it right there. Yeah, I mean, this is—this is the Gen 3 that’s out now, but uh, when you think about the amount of integrated electronics and circuitry in there, right, and battery life, it’s got four or five days of battery; it’s got a multitude of sensors and lasers and Bluetooth; uh, I mean, it is amazing. It’s the beginning of what we’re going to see in the—in the wearables revolution. Well, when this integrates with—Labs, you know, genetic testing, you know, um, uh, you know, body scans, all of these different modalities, when AI is able to pull all of that into one—one place, you know, the thing I—I—I’m really uh, a fan of wearables for is, you know, Oura, Whoop, um, these guys can do uh, studies that I think are more um, important than individual randomized clinical trials, because when you take, you know, six people or eight people and you send them to the University of Miami to do a sleep study and they walk into a sterile room that’s like two clicks shy of a jail cell, you put the monitors all over their body, and you tell them to go to sleep, um, versus you get a thousand people or 5,000 or 10,000 people to opt into a study with Whoop or with Oura, and you’re studying them in their own environment or in their own family, sleeping in their own bed and, you know, in their own habitual pattern, I think you get better data; you—you—you do. It’s uh, it’s amazing, and I—I’ve got—eventually they’ll be implantables. I’ve got a—if you feel this right over here—there’s a—wow—a little—a little glass capsule in there. Oh, you’re next level. What is that, dude? What is going on there? That’s my business card. Is it really? Yeah, I’ve been chipped first. Really? So I was on stage—I was in stage in—in Amsterdam; it’s a singular University event, and uh, the guy was there showing the future of implantables. This is like—God—12 years ago, really early on. That’s how long—that’s been. Yeah, it’s been in there, and so it’s a—it’s a non-bioactive glass, and inside is a uh, near-field uh, reading device, so an NRF, and it’s like when you chip a dog, MH, you know, and you can read—that’s what this had—my business card on it, but eventually it will be measuring everything—not, you know, not on the surface but subdermally, MH. And so these are coming—my Venture fund, we’ve invested in a number of these. Really? Yeah, that’s so fascinating. Uh, Tonal, um, you know, uh, I love the device for its ease of use, and it’s all about consistency, MH—it’s all about consistency. You know, I use an InBody—I mean, I love the devices—oh—to measure your—yeah, and and again, it’s gamified, so last year I focused on adding 10 pounds of mass—my muscle mass—and it was like consistency in the gym, five days—if I could—six days, creatine, 150 grams of protein because I weigh 150 pounds, and it was like just measure, measure, measure, measure, measure—to play that game. Yeah, and you have to want to play the game. Yeah, but and you also have to enjoy it, and you got to have the—you got to have trackable things to track it, like this. Yeah, and then I love my sleep—my Manta sleep mask. This is the—there—there are three versions of it; this is the most advanced version with a—with speakers in it. I actually don’t use this one; it’s a little bit heavier, but um, I—I—I can’t sleep without it; I can’t sleep without a—I also use a—I don’t—I don’t have it on the list here, but a mandibular advancement device; it is a upper and lower—upper—upper and lower uh, device that moves the jaw forward—the mandible—that opens up the airway, keeps you from grinding my teeth, and the Oura ring, the Manta, the eight Sleep—my—those are my—my—my sleep kit. I like—I am just throwing as many hacks as possible, but I—I—it’s like I travel with this stuff and and my slippers—got my slippers—I’m at home, uh, and that’s—you know, we talked about the eight Sleep cooling mattress, and uh, it’s really for me maintaining that body temperature uh, at—you know, I put—I’m fascinated by how much of an impact just slight—CH—changes in temperature variation have at holding you into—because I notice I will sleep the same length of time, but my REM and deep scores will not be as much, and when I look back at what the eight Sleep is doing—changing its temperature to hold you in deep sleep, to hold you in REM sleep—I mean, honestly, how it even knows that is wild to me, um, but it—you know, my—my Whoop will validate that uh, you know, as well. And people should know on your sleep, um, there are two important phases, right? There’s your deep sleep, which typically occurs in the first half of your night’s sleep cycle, MH, and your deep sleep is where your glymphatic system is clearing proteins—toxic proteins—in your—in your brain, and if you have to choose, you know, deep sleep is I think more critically important for our long-term health. REM is where you’re consolidating memories, and REM will typically occur at the later stage of sleep cycle, so right—if you are getting good deep sleep but you wake up four hours after you start, you might get an hour—you know, I try and get at least an hour of deep sleep and at least an hour of REM sleep is my—is my goal, and it’s hard to control that. The only way I control it is no alcohol, no food for a couple hours before, and getting to sleep early, and when I do that, I’m typically getting to that great cycle, but if I wake up after a shortened sleep, the deep sleep’s there, but the REM has been eliminated. Yeah, yeah.

Um, so you know, I’d like to wrap with a conversation on a technology that um, that we’re both passionate about uh, which came out of DARPA uh, called Extera. Yes, and their filter uh, let’s—so I’m going to have Extera on stage with me at the Abundance Summit, you know, this year for the first time, so every year at the Abundance Summit, which I hold in March, I’ve got um, you know, a day on AI, a day on exponential technologies, a day on moonshots, a day on—on uh, on longevity, and this is the first year that I’m really going from a focus on diagnostics to have focused on advanced therapeutics. I mean, the tech to enable you to extend uh, your life and to really uh, cure—prevent diseases is finally coming online right now. I’m a huge believer in the Extera. Yeah, please. So—um, I—I—I did a podcast with Dr. Mink Chala, CMO—offic—yeah, he’s a chief medical officer there, and it’s worth a watch if—if uh, and please—the—the Ultimate Human podcast. Yeah, the Ultimate Human podcast. But um, so Dr. Chala is a nephrologist; um, he was an ICU septic specialist. You know, one of the challenges in ICU is that people get sepsis; um, it’s pretty common; you’re—ven—bacteria in your blood—bacteria in your blood—very painful, very dangerous—very dangerous. I mean, it’s sometimes not painful because you’re not conscious, but you know, but but very, very dangerous nonetheless, and and a part of what happens is—can shut your kidneys down, so he was a nephrologist, so obviously he’s been studying how the blood is filtered uh, throughout—throughout his entire career; he’s also published some unearthly amount of of peer-reviewed studies; it’s well in excess of 100. Sweetheart guy; he’s a sweetheart of a guy. Ian—he—one—literally one of my favorite humans, and I’ve been talking to him about spike protein detox, but um, and so this filtration system uh, that that he’s uh, co-developed has um, uh, not just filters, which most filters are uh, filter based on size, right? So that—so a filter will be a step-down filter will have progressively decreasing um, SI pores that things can get through. Yeah, exactly. And so you’re filtering things out by size, but when you’re—when you’re filtering the blood um, and you’re filtering it by size, like you want to get down to the size of the micron size of a virus, well, now you’re going to take platelets and all—you’re going to take all kinds of growth factors; you’re going to take all kinds of useful things out of the bloodstream, so you—what you’d prefer to do is creating a binding affinity, and if you could, you know, selectively create an affinity um, that attracted things like viruses, uh, mycotoxins, circulating tumor cells—which is fascinating to me that you can get circulating tumor cells—uh, bisphenols, microplastics, um, and you could create this binding affinity, and essentially what these Hep binding sites do, you know, aside from increase the surface area inside this filter, is they sort of mimic the wall of the artery—the glycocalyx—yes—and uh, and so—which a lot of pathogens have a natural affinity for because that’s how you leave the blood and enter the tissue—the way—the way—when he was speaking at my Longevity Platinum trip, he said, listen, you typically have these things that are circulating through your blood, and if they’re trying to—ATT—attack you, they need to attach to the surface of the blood vessel, M, and then enter through that, and our blood vessels are coated with this glycocalyx, this large protein structure, and um, he built this uh, this filter—call it the SE—Sephora—sarif—serif—sarif filter—and uh, the number—I remember it’s a tennis court-size surface area of this glycoprotein that your blood flows through. Mhm. And so if your blood has any kind of viruses—and we are constantly building up these viral loads—th—%—I mean, I—you know, we were talking before the podcast, and I’m a big fan of this sort of emerging viewpoint that aging is this process of immuno fatigue. Yes—immuno exhaustion—is immuno exhaustion. Yeah. Um, so it’s—you know, the immune system is just fighting on too many fronts; you know, eventually we’re—we’re sort of micro-poisoning ourselves to death; we’re bathing our cellular biology in this toxic soup, um, even—even those of us that are trying our best not to. Um, and if you could filter these pathogenic compounds, including a lot of the inflammatory compounds, out of the human—out of the bloodstream, now all of a sudden you give your immune system a leg up, you know, so—um, you know, so mold—molds—toxins, U viruses, um, you know, they have some really interesting data on long COVID, and you know, 27 million people report suffering from long COVID; they can filter long COVID out of your blood—two or three filters—it’s incredible. Amazing that gives somebody their life back. It—it does. And the way I think about it is the following: uh, we are living in this world of—embedded with viruses, and we get a—we might get a CMV, we might get an Epstein-Barr virus, a—um—a shingles—sh—yeah, all of these viruses, and they don’t go away; they’re embedded in your cell—in your DNA, and they flare up—literally wound into your DNA—and and it turns out your innate immune system—your natural killer cells—are there, and they have two primary functions: one is they’re looking for cells infected by viruses and killing those cells; the other one is they’re looking for cancer cells, MH—the—cting—cells—Y—and if you are bombarding your body with these embedded viruses that you’re getting, and you get a cold and you get COVID on top of that, you exhaust it to the point where it cannot battle on all these fronts, right? And so when you put one of these uh, filters, and you literally are taking the blood out of your body, you’re filtering it over this tennis court size of glycocalyx—all of those uh, those, you know, pathen—tumor cells, pathogens get—get pulled out, and you return it to your blood, and then your immune system is like, ah, it’s a field; we go—we’re going to go sweep up all the guys that are left. Yeah, I think it would be a great treatment to do before you did biologics, so if you were doing stem cells or exosomes or a natural killer cell treatment or one of the other advanced biological treatments, to actually have a clean slate. Yes, you know, um, one of the things that we do for, you know, athletes and other folks that are leaving the country to go do stem cell treatments is we say, well, let’s take 10 weeks and really get your blood as clean as we can, right? That’s—let’s lower—you don’t want to hit your body with stem cell treatments if if you’ve got any kind of cancer in your body or anything that the stem cells could activate uh, continuous. Yeah, and not only—not only that, you don’t want to do it if you have, you know, hyperinsulinemia, you know, a lot of pro-inflammatory cytokines or, you know, very high C-reactive protein, high homocysteine—these—you know, stem cells have an affinity for inflammation, and you want—you want the inflammation to be in the areas where you need the stem cells to go to work—not just sort of dispersing once they get to the—to the bloodstream. Yeah, buddy. Um, tell everybody where they can find you. Uh, my first and last name, just at Gary Breau on Instagram or at uh, The Ultimate Human. My podcast is The Ultimate Human. Um, I have a community; I write—I—I write a free newsletter every week; I—I write challenges and guides; I host uh, free challenges um, about every other month—cold plunge challenges, breathwork challenges, whole-food challenges, gut uh, gut challenges—all kinds of things, and people go through a community—with a community—go through that challenge together. I—I have a—I have a paid community that’s 97 bucks a month; I do um, four private podcasts a month with that community, do a lot of one-on-one like uh, you know, Q&As, um, bring lots of special guests on there; I’ve had Dana White, Jelly Roll, Stephen A. Smith, you know, lots and lots of fun folks uh, on our challenges. I have a free challenge coming up in—in February, which is uh, my morning routine challenge, uh, so we’re going to go through the science and morning routines—the science of circadian rhythm; I stayed with them for three days; we’re actually measuring sleep scores; um, it’s a really, really cool, fun, active, engaged community, and you know, listen, if you want to make a change in your life, doing this with a community is the number one way to do it. Yeah, for sure. And that’s what we’re trying to do at—that’s what we are doing at The Ultimate Human is just building a community, and we call them the Ultimate Human VIPs, um, so you can go to theultimatehuman.com, read—read what it would be like to become an Ultimate Human VIP. Um, so I’m back in Miami at the end of February; the FI Summit is happening down there; I’m—I’m coming through to play with your toys. Let’s do it, man. Round—you’ll get—we’ll do a podcast in the hyperbaric chamber. Oh, I love that. All right, awesome, Peter. All right, well, my friend, thank you. Take care, everybody. Live healthy. [Music]

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Transform Your Life with AI Health Breakthroughs | EP #149

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