Hello, hello, hello, and welcome to a very exciting week at the Kalish Institute. Gosh, where do I even start? I don't know. I don't know where to start. My life is just so charmed at this point. We should probably just talk about H. pylori or just ramble for like an hour.

But I would say that this year, just so if you guys want to meet me in person, it would be great. I'll be at the IFM International Conference, their annual conference in Florida, which is coming up not too far away, in May. Be in Japan at the end of May. If you happen to be in Japan, we'll be speaking at their anti-aging conference. And then I'll be in Portland, Oregon in July for a week where IFM is going to be teaching several modules. And then I'll be in Nashville in October. If you guys are local to Nashville, I'll be at the IFM conferences and modules that are being taught in Nashville.

Anyways, there's lots of opportunity to meet me. Basically, just look at the IFM schedule, and I'll be at all those events. And my office and my, my class will have a booth at most of those events, not all of them, but most of them. So you just come look for the Kalish booth. I'll be hanging around and always like to meet people in person. And always encourage you guys to go to IFM conferences too, because you learn a lot.

So, we're going to talk about, I want to talk about H. pylori tonight. And I want to talk about my latest understanding of this after having treated it for so many decades. And I want to kind of upend our thinking process a little bit. So tonight's gonna be challenging thought-wise, but let's just jump into it and see where it takes us.

So, I'm gonna start off with a really simple story, which is started 20 years ago. There's my son. That's when he was, I don't know, three or something like that. And what a cutie he was. With me, a great guy. And then, then he grew up. I don't know how that happened. But there he is now. He just came home for Christmas. Very proud of him. He's at Washington University in St. Louis. He's not doing pre-med. It's a very well-known medical school, their pre-med department, but he's doing math and physics. And super happy to see his life too.

So, well, he's got a summer internship doing research as a freshman at the biophysics labs at Wash U. And off and running. But the reason why we're talking about my son is because when, you know, I raised this kid and, you know, spent a lot of time with him for a long time. I was a single dad. And, you know, very close to this guy. You know, put a lot of energy into him. And, you know, loved him very, very much. And still do.

But then, you know, a knock in August, he just decided to get up and go to college. And just grabbed it back, back in a couple of boxes. And his mom bought him some sheets. And he was gone, you know. And so, what did I do? I got really stressed. You know, it was the first time that I had had a weekend with nothing to do since I was like 25 years old. And so my response to that was not very good. You know, I, I sat around. I ate a lot of ice cream. I ate a lot of pizza. I put on all this weight. I got kind of fat. I stopped exercising. I'm so. It's like a little bit like being depressed, but I wasn't sad. I was just like sitting in my house going, well, what the hell am I supposed to do now? You know, after all these years of being a parent. And I also had raised, you know, several stepchildren. So there's a lot more kids in my life than just my son. And anyways, all of a sudden, I found myself single and with all this free time. I didn't know what to do with myself. And, um, my health took a precipitous decline. Thankfully, I snapped out of it and I'm back to working out and eating normal and being healthy.

But the point is that when we're under stress, sometimes you don't really know it. Like, you wouldn't think your kid going to college would be that big a deal, but it was for me. And when we're going to talk about tonight in regards to H. pylori is how we respond to stress on a physiological level and how that impacts everything about our health. You know, and I actually did, after a month or two months of eating ice cream and pizza and burgers and fries, I did start to develop heartburn. Although I don't think I picked up H. pylori. But, you know, the whole point of this is that we, we've got to look a little deeper, a little deeper into what we're talking about here.

So for those of you that are new to me, I've got a few intro slides. I've been in practice forever. We've trained a lot of people. I teach this amazing mentorship program, which you guys should all take. And we're signing up a new class in a couple of weeks. If you've been thinking about taking the mentorship, you should jump on board because I've developed a whole bunch of new tools right now. I created a whole new Fundamentals of Functional Medicine section in the mentorship, which is, I don't know, I think it's 15 or 20 hours of curriculum on program design and a real nitty-gritty clinical application of functional medicine. We've also now, or I've been working with Dr. Richard Lord for two years now, day and night, on developing new content for the class in terms of lab interpretations. So it's a robust and really intense community. I'll give you a little tour around it in a few minutes. But if you're thinking about taking the class, it's a really good time to do it because it's gotten incredibly good. We haven't really raised the price. It's still the same price, they just keep adding more and more stuff to it.

I was originally trained by naturopaths, you know, and what I want to kind of focus on tonight is the stress response. Like in my case, my son going to college, you know, it could be someone going through a divorce. It could be a lot of different things. And how that stress response impacts secretory IgA, and how it impacts what we eat, and how it impacts our microbiome, and how that impacts H. pylori. And so, you know, in my early years of training, in my early, my first 10 years of understanding this, life was very simple. It was, I see there's H. pylori on the lab. I see a patient that has a bunch of symptoms. And I get rid of the H. pylori and the symptoms get better. And I now understand it's so much more nuanced and complex than that. That tonight, I just want to really think through some of the deeper ramifications of what we're doing and what the organisms like H. pylori are. And, and I now realize that they're on a spectrum, right? They're on a spectrum from potential pathogen to full-blown pathogen to not causing any problems at all. And what determines where that H. pylori is in terms of its pathogenicity is what its stress response and the health and functioning of our microbiome.

Okay, so let's say that again. What determines whether H. pylori is going to cause vomiting, nausea, heartburn, pain, and bleeding and ulcers in a horrific symptomatic expression, or if H. pylori is just going to be sitting there, maybe even doing some good things and being protective, is the state of your microbiome and the state of your mind. How stressed out you are. But look at me, when my son went to college, I mean, how many pints of, you know, I don't like Ben & Jerry's at all. In fact, if you put a thing of Ben & Jerry's in front of me right now, I probably would like not even eat it. But Haagen-Dazs, I could eat. You know, either butter pecan, rocky road, or coffee. Haagen-Dazs, whole pint, no problem. And I could eat like a half a pizza too, you know. After doing that for long enough, we just imagine what my microbiome was like, right? No wonder why I started to get heartburn.

So these things are intertwined, right? Stress, stress eating, the microbiome. This is all really connected. And we'll talk a little bit more in detail about that.

So then, this approach, right? Is the Kalish method, whatever you want to call this, is like the common sense method. Is to reduce inflammation through diet and lifestyle, to restore the microbiome, to restore the microbiome, to restore secretory IgA levels, and then kill the bugs. In fact, if you restore the microbiome functions and restore secretory IgA levels, you might not even need to kill the bug. So that's the ironic part in all this. Yeah. So just want to keep that in mind. It's a bigger picture. It's not the H. pylori that's the problem. It's the destruction of the microbiome and the stress-induced problems with secretory IgA that are the real problems. And it's very easy to just get caught in this idea that we're just gonna kill the bugs and people are gonna get better. And it's just too simplistic. And it doesn't work, especially for chronically ill patients with a lot of GI stuff.

Okay, so common failures using the wrong treatment sequence, right? Just, oh, there's H. pylori, I'm just going to treat that. And I'm gonna ignore the microbiome, ignore the diet, and ignore the stress. That doesn't work very well. Okay. We want to restore everything first, then kill stuff, and then restore it even more. That's kind of like the goal. And there's also lab testing issues, you know, you can miss stuff on labs pretty easily. So you want to be careful about that.

So, and when we're talking about stress, talking about cortisol, or talking about, you guys should know this pretty well, the adrenal thing, the HPA axis, right? We're under stress. What matters for tonight, when we're under stress, is that it, the stress interferes with cortisol. And that interferes, in turn, with secretory IgA, which is the immune response in the gut. So we end up with this weakening of the immunity and the gut lining. And that allows for parasites, bacteria, needs to start to proliferate. Okay. What's equally important, and perhaps even more important, than the stress response is the health and integrity of the microbiome itself. And I'm gonna show you some different slides in a moment about that. Okay? Because I think that's really like the mission-critical part of this. And I get patients all the time who have had H. pylori or had Blastocystis. We had one this morning, she had Dientamoeba fragilis. It almost doesn't matter what the GI bug is, practitioners tried to treat it, wouldn't go away. Why didn't it work? Okay, because we're not doing this on a symptomatic level. And we're not doing this just to kill bugs. We're killing bugs in the context of strengthening the immune response and strengthening the microbiome, which in a way, you could argue, is kind of the same thing.

Okay. So if your patient has anxiety, acid reflux, fatigue, it really doesn't matter what the manifestation of the H. pylori problem is, right? A lot of the patients that I work with with H. pylori, they're just like vomiting every morning. That's just, they just get nauseous. They wake up, they throw up, and then they go on with their day. I can't tell you how many patients, more patients than I can count, who have that as a chief complaint. I mean, that's so frightening to think that you'd just be that sick and not knowing that it was H. pylori, right? It could also be completely removed from GI symptoms whatsoever, right? A hundred percent removed from GI symptoms. And that's why these GI bugs get to be so slippery. Because what if you have H. pylori and that's actually causing your fatigue, but there's a complete absence of digestive symptoms? That it's a very difficult thing to wrap your mind around, to know what to treat. So the patients are always going to relate to clusters of symptoms. So the fatigue, or the heartburn, or the bloating, bloating. But we want to take a bigger picture, take a step back.

My, you know, I'm very deeply involved in a Taoist meditation practice, knowledge. And my teacher is this man named Gerard. And I see him every Friday. And we spend three or four hours together. And every week, he says this one thing. So I know it means I haven't understood it yet, but I want to try to at least quote him. He's like, "Dan, you're looking at the grains of sand on the beach. You got to take a step back and look at the entire beach." So we're with the grains of the sand, and our situation here is the H. pylori, and getting overly focused on the heartburn and bloating and the fatigue. Taking a deep breath in, we're taking a step back and we're looking at the whole beach. And then we see stress, microbiome, adrenals, you know, as the real reason why the H. pylori has become a problem.

Okay. So we can't just ignore that. We need to treat and correct all the body systems in this general context. And if you can do this and do this successfully, you'll get H. pylori every single time. I mean, I still want to kill this stuff, right? We're not saying we're not going to want to kill it, but we want to address all the body systems in an integrated way and not just isolate the GI. And the most common error that I've made in practice, and I see still a lot of doctors make, is to treat GI first. And I don't think that's a good idea because you need to take the time to strengthen the microbiome before you do any killing. To strengthen the secretory IgA response, the immune response, before you do any killing. All right. And if you can do that, then you'll be the master of treating H. pylori. It'll actually start to seem kind of easy. And it might even get a little boring.

So I'm just going to cut over to a slightly different slideshow for a moment because I'm switching things around here. Apologize about that, but just give me one sec here because I want to talk a little bit about when I say microbiome, what I mean was this guy. You've been talking about. And let's look at some of the specific bacteria that we're talking about here. They are. So these, these are the commensal bacteria. These are normal, healthy bacteria. Everyone agrees you're supposed to have these. Not a lot of controversy. And they're divided up into, in this diagram here, you know, different categories. Okay? There's hydrogen producers, hydrogen consumers, and then there's some of the key organisms here, like Methanobrevibacter smithii, the sulfolobus, pyrococcus. All right. And these bacteria are pretty interesting in that they do different things. They make hydrogen, some of them consume, some of them live on sulfur. They have their whole own lives going on. And they're doing their whole own thing. And in general, they are highly responsive to foods that we eat that will either encourage them to grow or discourage them to grow. You can, of course, also use probiotics and prebiotics supplements. But obviously, the foods are a better way to go.

So this then brings up the question, is are the pathogens bad? If you have H. pylori and a healthy microbiome, are you going to have symptoms? Probably not. If you have H. pylori and a damaged microbiome and a lot of emotional stress and your sIgA is low, then H. pylori is gonna cause a problem, really consistently. So some of these organisms, like H. pylori, are kind of on a spectrum, right? They can be good or bad depending on the host. Some of these organisms, I would say, are always bad. Like, I mean, I have some, like I always think E. histolytica is bad. I don't think there's a friendly version of E. histolytica. But I think there is a friendly version of H. pylori, just depending on what's going on.

And so a couple things, bacteria, just to keep in mind. M. smithii, D. hadar. These are the hydrogen consumers, right? And they have their whole own thing going on. They can be related to cardiovascular disease, to obesity. There's, there's a whole own thing happening with these good bacteria. There's, these are the ones that remove hydrogen, D. hadar and M. smithii. So there's bacteria that produce it, there's bacteria that remove it. And they can be tied into everything from ABE to fatigue, neurological problems. We've got all kinds of research here. I'm just gonna kind of flip through these kind of quick. There's the gut bacteria. They can measure gut bacteria changing and changing and bringing function. Okay. So we just want to keep that in the back of your mind when you're thinking about the H. pylori, that there's a lot of other bacteria going on here that are setting the stage for the H. pylori becoming a problem.

So when you're going to target and kill the H. pylori, it's gotta be in the context of the general microbiome and its status. And if you ignore that, then people aren't going to do very well. And you can get a pretty straightforward improvement in the microbiome just by changing that person's diet in the first couple of months before you start to go after and kill the H. pylori. And there's two general ways you can do that. There are, you know, foods that have the fiber that the bacteria need to grow. And those foods are called beans. Pinto beans, black beans, lentils. It could be hummus. It could be navy beans. People need to eat beans to get the fiber for these commensal bacteria to grow. Second category, polyphenols. Polyphenols are found in fruits and vegetables. The bacteria feed on the polyphenols. And hence, one of the major benefits of eating fruits and vegetables. So increasing fruits and vegetables, increasing beans in that first couple months sets that person up to start to grow the healthy micro bacteria, the healthy microbiome. The healthy bacteria started to come back. And then when you get down to killing the H. pylori, you should have a much easier time.

And just as a total aside, because you should know this, and honestly, I think most of us don't know this. And I'll tell you, everything that I teach is something that I learned and was so embarrassed that I didn't know that I remembered it. So now I'm teaching it. So don't feel bad if you don't know this. But you're supposed to know this. But how are you supposed to find out that this? I don't know how you're supposed to learn this stuff. But you're supposed to just know this through osmosis. But let me just show you, if you're running organic acids profiles, there's a really important part of the test here. And it's measuring these polyphenols. Remember I said that you need two things for a healthy microbiome? You need bacteria to grow from feeding on the fiber and beans. So everybody needs to be eating beans to get the fiber for these commensal bacteria to grow. Second category, polyphenols. Polyphenols are found in fruits and vegetables. The bacteria feed on the polyphenols. And hence, one of the major benefits of eating fruits and vegetables. So increasing fruits and vegetables, increasing beans in that first couple months sets that person up to start to grow the healthy micro bacteria, the healthy microbiome. The healthy bacteria started to come back. And then when you get down to killing the H. pylori, you should have a much easier time.

A neurotoxin. So if you see a high level of D-lactate, it means there's a gut problem that's damaging the brain. I'll say that again. If you see a high level of D-lactate, it means that your gut problem, your H. pylori, or whatever it is, gut problem is directly damaging the brain. Okay? Because D-lactate's a neurotoxin. That's what it does.

And in this case, look how high it is. So D-lactate is considered a problem if it goes above a 2. The 95th percentile is a 4. That's the highest it should ever be. And this patient is at a 16. So we're talking about a marker that elevates between 2 and 4. 16 is four times the highest level, right? This is extraordinarily high D-lactate. You're guaranteed to have cognitive symptoms. What would that be? Memory problems, fatigue, brain fog, all that coming from the gut.

So this is a wonderful marker to tie in this relationship between H. pylori, dysbiotic bacteria, and the brain. So the patient's saying, "I don't know, doc, you know, I'm tired and I'm so spacey, you know, I can't remember." When I had this, I had a real estate agent this morning that was a patient. This was a bad one. And she said, "I was showing some people a house the other day, and, you know, I brought them into the house, I opened the door, and we walked in the door, and I forgot what I was doing." It was like she kind of momentarily didn't know where she was or what was happening, and then she had like a panic attack and freaked out. So, I mean, some people with this kind of a problem, gut-related brain issues, and when she's almost unable to do her job of just showing her customers or clients a house, okay?

So just keep that in mind as a connection, right? H. pylori is gonna cause this imbalance or be associated with this imbalance in the bacteria. D-lactate gets out of control, and you walk yourself right into a brain-related problem. I want to show you another manifestation of that right here. Same patient, right? This is another way of saying the same thing. You're gonna be seeing kynurenine on all your tests. You're running organic acids. If you're not running organic acids, you should start running organic acids. I can't imagine how you can't have a functional medicine practice without organic acids. Let me just say that. You know, you can't. And you gotta, if you, if you don't know how to interpret organic acids, just take my class. Just dish out the money. You'll never turn back. You'll never regret it. Most everybody that takes my class makes the money back that they're investing in the class even before the class is over, okay? We'll get you up to speed and learning how to interpret these. But don't try to practice without organic acids. You'll just be completely hamstrung, okay?

Kynurenine. We talked about this a little bit earlier. Let me just show that image one more time. Get over here so you guys can see. To do, to do. Now, kynurenine, what does that mean? Well, we already saw the D-lactate. Now we're seeing that this kynurenine pathway is heightened. Kynurenine levels are up. That means that serotonin levels are down because tryptophan is going down the kynurenine pathway, okay? So when you're inflamed, H. pylori, dysbiosis, tryptophan goes this way, over to kynurenine, and then it doesn't go towards serotonin. So kynurenine being high due to gut inflammation is going to knock your serotonin down like a rock. What does that make people? Anxious, depressed, grumpy, moody. Not a happy place to be.

So look at just one patient. How much you can learn. Kynurenine is high. Inflammation in the gut triggers that. And we also saw the D-lactate high, which is a neurotoxin. So this person's brain is getting munched up by the gut bacterial problems associated with H. pylori and dysbiosis, okay? And I know this is crazy, but I'm going to say this one more time. You could have high D-lactate, high kynurenine due to H. pylori and dysbiosis with no digestive symptoms. A hundred percent of the symptoms could be cognitive. Could all be in the brain, okay? And that's actually surprisingly common.

I'm going to show you one more example and I'm going to shut up and take some questions. I hope this is helping you guys. Oh, this is a good one. This is a really good one. This is this one. Let me see. This is as good as I think it is. Oh, yeah, yeah. This is where they make. Yeah, this. Well, yeah, this. Let's do this one because this will teach you something that you should know, right? So H. pylori. Now, where in organic acids? So we're looking at how the H. pylori manifests. Remember I said in the beginning, kind of obvious, you have a stomach infection, your stomach's messed up. We're talking about H. pylori gone bad, not H. pylori when it's protective. We're not talking about H. pylori when it's protective because that's not very interesting because those people are fine and we don't care about them. They're alright, okay? We care about the ones where the H. pylori has gone bad.

And one of the things that would happen obviously, if your stomach is messed up, is that you don't make enough hydrochloric acid, which means you're not going to be able to absorb protein, right? You're not going to be breaking down and absorbing protein. So what's that going to cause? Amino acid deficiency. And look at this organic acid test. These are real patients of mine. These are not things I just made up. Look how low all these markers are. So we know that when organic acid markers are high, there's nutrient deficiencies. But what does it mean when all these markers are low? Oh gosh. And look at this. Look all across the board. It's just low, low, low, low, low. Under DL, as in underneath, detected, underneath detected limit. Does that mean they're low in B vitamins? No. Has nothing to do with B vitamins. When these markers are high, it means that the person's low in B vitamins. When these markers are low, categorically like this, this entire section is low, it means that there's not enough amino acids. And that was worth listening to this whole 45-minute rambling talk of mine just to learn that one thing.

So let's go back. I'm going to say that one more time because this is one of the most important things that I've learned in the last couple years. I use this trick every single day and it's life-changing for patients. I'm not kidding. This is like a win-win-win. So remember, we're talking about low, low, low levels of those organic acid markers. And what are we actually measuring in that section of the test? We're measuring the citric acid cycle. So we know that when these markers are high, it reflects a block and the nutrient deficiency. But what about when all these markers are low? Clearly, then we're not making cellular energy, right? It's not happening. It's like a car that's run out of gas. And that is what Richard Lord calls a hypometabolic state. There's not enough mitochondrial production of energy. And you can fire that up by giving that person amino acids so they start to repair their mitochondria. Freeform amino acids. We'll just zoom. This is a win-win-win.

So remember again, I'm trying to introduce new concepts. Low levels of these markers that are related to the mitochondria. Are they reported by the lab as a problem? Not really. You don't really see it. Like I'm gonna show you another example. This is trickiest. So I want to talk about stuff because you're not gonna learn anywhere else. Like, I don't know if you looked at this test here, honestly, you'd be like, "Oh, yeah, that one marker's low, but all these others seem fine. Yeah, whatever." But really, these are all low. That's low. That's low. Those are low. That's low. Those are low, right? This entire thing is a problem. In fact, this is another hypometabolic pattern, which is a much more severe and difficult problem to solve than when all these markers are high. So high levels of organic acids in general means nutrient deficiency. A pattern that's low in this section means patient needs amino acids desperately to fix the mitochondria. And remember, we already talked about this. I'm just doing a little refresher here. Remember, high levels of organic acids in this section, in the bacteria, can mean bacterial overgrowth. If they are extraordinarily high, low levels mean not enough polyphenols, not enough fruits and vegetables. Where do you want the levels to be? In a perfect world, they would all be in the high end of normal, okay? High end of normal is robust, healthy, good bacterial growth. Low means not enough fruits and vegetables. Extraordinarily high means there's some overgrowth problems or dysbiosis, okay? But just keep your eyes out for these low-level markers because they're tricky.

Alright, so I'm going to answer some questions real quick. I want to get my self-promotional slide up first so you guys don't forget that I want you to take my class because it's a great class. I really did spend six months building this whole new thing out and somebody's got to watch it. I've had like two or three people watch the fundamentals class. I think it's the best thing I've ever done. Program design, patient communication, it's all those nitty-gritty stuff they never teach you, okay? That's included in the class. We're not charging anymore. It's been six months doing that last year. Starting on April 24th, okay? Alright, let me grab some questions here. We got another eight minutes. I'm gonna go back to the beginning. Omar, go wash you. Go team. Marcos, kids went to a high C2. That's great. It's a wonderful campus. I mean, it's oh my gosh, I don't even talk about Wash U. Such a beautiful place. It's like Disneyland. Some believe H. pylori is normal and protective. It can be, right? Good ways to increase the SIgA. If we talked about cranking up the adrenal support. If you have virulence factors, do you always treat? So treating H. pylori is contextual, right? There has to be a problem. But if you see high D-lactate, if you see the commensal bacteria are messed up, if you see kynurenine is high, those are all things that mean you got to treat it. That's why I was trying to show you these other factors. If you see a lot of oxidative stress, you should treat it. If you see a lot of inflammation, calprotectin is high, you should treat it, right? So if you're seeing the H. pylori triggering damage, if, remember I showed you that amino acid thing, if you see low levels of amino acids on the energy portion of the test, you should treat it because these are all telling you that H. pylori is causing problems. You're seeing the ricochet effect of H. pylori. And I still do believe, as I was taught, as is naturopathic theory from the beginning of time, that the gut is the center of the naturopathic universe. The gut is the center of many of the health problems that we're dealing with. And so I don't want to diminish H. pylori. Actually, I want to elevate it and just say, hey, we respect H. pylori so much that when we decide to kill it, we want to be circumspect and careful and plan it out and not just, you know, brazenly walk in and try to knock it out. So protocols for low SIgA are DHEA and pregnenolone. I think I just did a free webinar on this last month where I gave away all my sort of secret, secret DHEA and pregnenolone programs. If you haven't heard that, go back and listen to the last free webinar on the adrenals because I just wrote out and taught all the secret stuff that I used to keep in the mentorship only. Why did I do that? Because I got so much new information coming into the mentorship. But I used to be my most prized intellectual property. I'm just giving away for free now so you guys can learn how to do that. You don't even have to pay anything, okay? So blood tests, yes. So there's, you can do a blood test for the antibodies, a totally valid and wonderful test. You can do stool antigen testing and you can do the PCR DNA-based testing. So there's three different ways to do it. You can do all three if you're compulsive. If you just do one, you know, I try to do stool antigens and the DNA testing, okay? If the blood tests are elevated, it can mean different things, right? Because those are antibody tests. So not everybody that has a positive antibody needs to be treated. Those are kind of tricky. Hiatal hernia with H. pylori? Yeah. So I'm a chiropractor by training. My chiropractor that I first saw, Richard Robert Shaw, still in practice to this day. I was driving my old, this is like I was 22 years old. You can just see Dan driving my Alfa Romeo. German guy around. My dad had just died. I inherited 100 grand. First thing I did was go down and buy an Alfa Romeo. Maybe not the best financial decision, but what the hell. My dad, I just, was dead. I was like, screw it, I'm gonna buy a car. So I'm driving my Alfa Romeo around Berkeley, California. And then I get in my car one night and I'm like, wow, I can't drive. It's night and I couldn't focus. I couldn't see. If I looked at the dashboard, then I looked up, I would get such a bad headache. I literally couldn't drive. I was like, this isn't good. Everyone's telling me, you need glasses, you need glasses. I was like, I guess I need glasses for some random reason. I went to see Richard Robert Shaw in San Francisco. He did one cranial adjustment on my skull and I could see again. I was like, wow, this is cool. Richard, I just do that. He was also a master of visceral manipulation as well as cranial manipulation. And so I went to Chiropractic College thinking that's what all the chiropractors did because I was like, this is what you did. Anyways, I obsessed on and learned how to do visceral and cranial manipulation. Total respect for it. If you're dealing with H. pylori and stomach problems, you should always have the stomach checked. If you don't know how to do it, you should refer out to someone who does visceral manipulation. There can be mild hiatal hernias that can make it really difficult to eradicate H. pylori. So always check the stomach on a physical level. I'm glad Margaux brought that up as a question. I treat H. pylori whenever I see it on a lab. If I'm suspicious based on all these other markers that I'm trying to show you tonight, okay? If H. pylori is high but the virulence factors are negative too, do I treat it first? Right. I always do the first two months of microbiome and SIgA first, unless you can't. For example, it's a woman and she wants to get pregnant in three months and you just don't have the time to waste on the setup. The kid that I mentioned who's vomiting and can't play sports, we're not going to torture him with a diet for two months. We just treat the H. pylori. If you have to treat it right away, do it. Your odds on you being successful will exponentially increase if you hold to that first 60 days and you try to reduce inflammation and strengthen the immune response. I do that as much as possible unless I can't. What happens when SIgA is super high instead of super low? So that just means it's a newer infection and the immune system is still upregulated. We still do basically do the same thing. It should be an easier case, though, okay? Again, if secretory IgA is high, it usually means that the person hasn't had that gut infection for as long. It should be easier to treat it. Now, you could argue you don't have to do the whole two months maybe of prep work. Maybe you do a month or a few weeks or something. So if SIgA is high, it's going to be easier to treat than if SIgA is super low. Super low means that initially high immune response has faded. So it's usually more chronic. If a patient can only afford one lab, that's a tough one. I probably do an organic acids to be honest, and then maybe a GI test second. Because if you just do the GI test and you see H. pylori, you still don't know enough, you know? Okay, this look, question. Do you consider any pathogens like parasites, use your bacteria, dysbiosis is the same way? Absolutely, yes. So a patient has Giardia, patient has Cryptosporidium, same exact conceptual framework. Boost up the SIgA or lower it, you know, normalize this again, right? If it's high, bring it down. If it's low, bring it up. Work on the adrenals, work on the microbiome, and then go on a killing spree for Crypto, H. pylori, Giardia. Dying to me, but fragile is the worst of all these bugs. And the one that we all miss the most is, you know, chronic yeast or Candida overgrowth. Don't forget about that. Hard to find Candida on the labs. Uh, yeah. So Mastic is an herb. You can buy from most of the supplements. Can you have people on colostrum? Absolutely, yeah. Yeah. Yeah. So for sure, you can do all the anti-inflammatory stuff while you're doing the killing or before. When do you check DHEA and pregnenolone? When we, I just, any time. If for its a female, I don't think you have to correlate it with a menstrual cycle. You can do it. Do it any day of the month. D-lactate can be associated with Candida. Yep. Ask that. [Music] See, is there H. pylori, parasites, which was already? Oh, that's a good question. If H. pylori, parasites, and other bacteria are present, would you treat first? I have a personal order that my teacher taught me, which I follow. There's, there's no science behind this. It's just what Dr. Tim did. So I do it. I always treat H. pylori first, get the stomach work, and then I go over after the parasites if they're present, and then I go after the yeast last. So I do H. pylori, parasites, yeast, just because that's what Dr. Tim has taught me. And he was a nice old man. I figured he knew more than I did. So I just do it that way unless there's some reason that you have to do it differently. Asking what if the markers are a mix of high and low? In or a mix of high and low can be a lot of things on organic acid. So I was saying how if those energy production markers are low, they clearly need amino acids desperately to rebuild mitochondria. If there's a combination of high and low markers, they need the amino acids, but not nearly as much. It's a, and you know, and you can solve those high and low people with, you know, things like CoQ10, magnesium, and other stuff too, okay? Let's see. Hey John, John Ross, my buddy, hope you're doing well. Let's see. Dosage of Mastic? I go high. So I don't know. I mean, a lot of stuff I'm telling you guys, just what Timmons told me and they worked so well, I never stopped. So I do a thousand milligrams of Mastic three times a day. I'm going to say that like five times in a row. I do a thousand milligrams of Mastic breakfast, lunch, and dinner. You can do it with or without food. If they have a stomach problem, sometimes it hurts if they take it on an empty stomach. So I usually give it with food. It's probably stronger on an empty stomach, but you're gonna get more negative feedback from people. A thousand milligrams is two 500-milligram capsules, right? So two 500-milligram capsules breakfast, lunch, and dinner along with the anti-inflammatory stuff. That's usually enough. And that is a boatload of Mastic. If you look at a lot of the supplement companies, it means a lot of different pills. So just think, a thousand milligrams, three times a day, if you really want to knock it out. What I mean, I ask your products do I recommend? You know, there's one important fact. Wade, and I'm gonna have to stop because we're running out of time. I could do this class for hours though. You guys are asking good questions. Alright, I'm gonna try to just get through this. We're going overtime, which I never do on the free class. It's gonna screw up the recording, but whatever. This is a really good question. You guys got to know this stuff. So, um, if you have a situation where the mitochondria are screwed up, if I'm gonna go over time, someone has to sign up for the class, okay? Let's see here. When we're talking about damaged mitochondria, you have to rebuild these things. You just can't look at them and be nice to them. You have to physically restructure and rebuild them. And that takes amino acids. I'm going to ask a simple question, and I don't think any of you are going to know the answer to this. What is the rate-limiting step in the synthesis of all proteins except for collagen? Type it into the little box thing if you know. What's the rate-limiting step in the synthesis of all proteins except for collagen? Oh, Patrick and John. Oh, yeah. Damn it. Alright, tryptophan. And who knew that? Well, John and Patrick both knew it. Tryptophan is a rate-limiting step in the synthesis of all proteins except for collagen. And what does that mean? If you're going to build mitochondria, you have to have tryptophan in the patient's program, or they're not going to be able to assemble these beautiful amino acids you're giving into mitochondria, let alone what other stuff that you need to assemble. So when you're putting someone on amino acids, either make sure that the formula itself has tryptophan in it, or what's probably as good or even better is add additional tryptophan, maybe a thousand, two thousand milligrams a day range, to the amino acid powder. You got to have tryptophan. And many of the companies that we use do not have tryptophan in the amino acid powder. That's a problem. There's a lot of history behind that. But let me see. All right, let me try to sift through these questions. You guys, this has been happening in the latest mentorship calls too. My Friday, what? No, my Wednesday. Is it Wednesday? No, Tuesday, 5 p.m. class. I don't know what's happened. These doctors are just like frenetic and they submit so many labs. We're having like these two-hour classes and this has been crazy. All right, let me see. Hang on a second. Now, I don't have a kid because my kid's in college, so I don't have anyone to go cook dinner for. So I'm just gonna ramble. Let me see. I'm gonna get through these questions real quick. A thousand. We said amino acid products. I use the stuff from Pure Encapsulations. It's called Amino Replete. It has tryptophan in it. But it's not a big deal if you use another company's. Just put in tryptophan. Do I offer shorter classes? Yeah, I have one that's just on organic acids and we have a ton of stuff. The free webinars are in a YouTube channel. Okay, I'm an RN. I want to learn about organic acids testing but can't find a lab I can order from. It's Beth. Yeah, so Beth, you would want to get that. You know, for organic acids tests, and you may need to order it through a chiropractor or acupuncturist or medical doc, or you can use Direct Labs. Direct Labs.com carries them. You can just get it from them. Yes, I look at the virulence factors. So they're really helpful and see how bad the problem is. So, you know, really doesn't change the treatment, but lets you worry more about what's going on. Visceral manipulation, the Upledger Institute. John Upledger. So look up Upledger. U-P-L-E-D-G-E-R. He has all the information on that stuff. I'm not even going to touch questions about SIBO. That's like a whole other night. We should talk about because I have some strong opinions about SIBO. But I don't want to, if I just say what I'm thinking, then you guys are going to misinterpret it. Could you use DHEA, progesterone cream? Now that pregnenolone works better, but you can use DHEA and pregnenolone and progesterone. But I wouldn't use just the DHEA and progesterone. I'm thinking since there, so if you want to do an adrenal program, DHEA and pregnenolone and progesterone on top of that, the three. But DHEA without the pregnenolone doesn't work as well, okay? Yeah, we absolutely use charcoal or diatomaceous earth or fiber to bind up stuff. How to treat SIgA is all done through the adrenal program. So that's the DHEA and pregnenolone. And again, I had a free lecture on that last month. You guys can do that. Oh, how long on the Mastic? Two months. If you get a metallic taste in the mouth, usually means there's a gallbladder problem or something else like that going on. So you want to check gallbladder. BCAAs are more for athletic stuff, and the freeform amino acids are more general. Yes. All right, so tryptophan versus 5-HTP. I'm gonna say it one more time. What's the rate-limiting step in the production of all proteins? All proteins is a big statement. All proteins is like, grab your arm. That's your entire arm. All proteins is your liver. All proteins is your brain. All proteins is your mitochondria. All proteins is all proteins, guys. Tryptophan is a rate-limiting step in all proteins. If you don't have enough tryptophan in your programs, people can't synthesize proteins. They can't make amino acids into proteins. 5-HTP, in some ways, is far superior for bringing serotonin up. That's a whole different discussion. We're not talking about that. Okay? I'm gonna say that again. 5-HTP is superior for bringing serotonin up. We're not talking about serotonin today. That's what 5-HTP is there for, okay? Do you follow level? Yeah, so we monitor people every six months when we're doing this. Can I take organic acids from you and then be able to order it from your client? Yeah, Beth, if Beth, if you really want to do this, just call my office and set up a talk and I'll talk you through how to do it, okay? And if you just want to do organic acids training by itself, we have it as a separate course and it's not that expensive. I price everything at around a grand a month, okay? That's kind of my general theory about how expensive things should be. And then we have payment plans so you don't have to, you know, it's like around a grand a month. Let me show you here for Beth. There we are. Classes. Go to my website on classes. But my practice plan is a business class. The one-year mentorship, and then organic acids only, it's $49.95. And, you know, it's probably gonna be around a grand a month, okay? Let's you do the payments. For someone going through your program, could count the hours towards hours for Certified Nutrition Specialist? I've done that in the past. I don't know, depending on the program. I'm happy to help you fill out paperwork because we have a huge number of hours in here. So it just depends on the program. But I have had some students do that before, okay? I don't offer CME's, but we often can do these other things. All right, so again, 5-HTP is fine for serotonin-related problems. But tryptophan, we're talking about assembling proteins. If the patient is inflamed and if the patient has a problem with kynurenic acid, they still need tryptophan, okay? You're not going to make someone worse giving them tryptophan. You're going to be improving protein synthesis. I'm going to sign off. I love you guys. This was a really great class. The questions were really wonderful, which usually means that you guys are into it. Call me. Somebody has to sign up for the class, or I'm not going to keep doing these free things, okay? Somebody's just got to bite the bullet, spend the grand a month, just figure it's time to do it. Dan's at a really good space in his life. You should do it before I retire or before, I don't know, like I could just go back to Thailand and be in a monastery and you guys won't have access to this. All right, so come on in, learn all this stuff, and I'll catch up with you next month when we do another seminar, okay? Bye for now. You.

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Treating H. Pylori

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