Transcription
The old I that's looking at you. The Reed-Sternberg cell is the topic of today's video, so let's get started. [Music]
The Reed-Sternberg cell is a large cell with two nuclei. Each nucleus has a prominent, eosinophilic nucleolus. Around the nuclei is a halo of clear cytoplasm, just like the hole directly looking at you. There is a Reed-Sternberg cell. It is a neoplastic cell derived from the B cell. Where is the B cell? In the germinal center of the lymph node. As you know, these cells that didn't undergo hypermutation to express their antibodies are the RS cells. Multinucleated or could be by-lobe nucleus. Our cells are CD15 positive and CD30 positive. When you see the RS cell on a background of B cells, it gives you the moth-eaten appearance. Creative pathologist, whoo-hoo!
Okay. Our cells are more easily found in the mixed cellularity subtype of Hodgkin's disease. So what do you think? Did you like this video? Please give it a like. Let me know in the comments what you think, and don't forget to subscribe and follow me on Facebook. Thank you so much. Until next time, be safe, stay happy, and study hard.